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The map label for this gene is thiM [H]

Identifier: 76819595

GI number: 76819595

Start: 125992

End: 126882

Strand: Direct

Name: thiM [H]

Synonym: BURPS1710b_A0097

Alternate gene names: 76819595

Gene position: 125992-126882 (Clockwise)

Preceding gene: 76818856

Following gene: 76819318

Centisome position: 3.96

GC content: 74.19

Gene sequence:

>891_bases
ATGCGCAAGCGCACGCCGTCGAGCGCGCGAGCGCGCGCGAACGCAATTTGGAACGACACCATGGAATCGATCAGCTGGAA
CACCCCGTCCGTTCGCGACGCGCTCGCCGCCGTCAAGCGCGACGCGCCGTTCATCTACGGACTCACGAACTATGTCGCCG
CGAACCTGAGCGCGAACGTGCTGCTCGCCGTCGGCGCGGCGCCCGCGATCGGCGCCGCGGCCGACTGGCCGGCGCGTTTC
GGCGCCGGCGCGAACGCGCTGTGGATCAACACGGCCGCGCTGATGAGCAGCGGTGCCGACACGCTGCTCACGGCCGCGCG
CGCCGCGTCGAAAGCCGGCACGCGCTGGGTGCTCGATCCGGTCGCGCTCGGCGCGGGCGCGCCCGAATACGACGCGATCG
TGCGCGATCTGCTCGCCCTGCGGCCGACCGTGATTCGCGGCAACGCCAGCGAGCTGATCGCGCTCGCGGGCGGCACGGCG
GCCGGCAAGGGCGTCGACACGACCGCGAGCCCGGAAAGCGCGCTCGCGTTCATCGGCGATCTGGCGCGGCGCAGCGGCGC
CGTCGTCTCGGTGAGCGGCCCGACCGACTACGTGACGGACGGCGTCGCGACACTCGCCGTCGCGGGCGGCGATGCCCGCC
TCACGCGTGTGACGGGCGCCGGATGCGCGCTCGGCGCGCTGATCGCGGCGCTGCTCGCGCAACGCGGCGCGGCGCTCGCC
GCCGCGAGCGCCGCGCACGCGATTTATGCGACCGCCGCCGAGCGCGCGGCGGACGCGCGCGGCACCGCATCGTTCGCGGT
GCGCTTCGTCGACGAACTGTCGCTGCTCGATCCCGCCGAATCGTCGCGCGATCGCTCGGCCGGGCAGATCGGCGCGAAAC
GGCGCGAGTGA

Upstream 100 bases:

>100_bases
TGACGACGATCGCTGCGCACGCGTGCCGGAACGTTTACAGTGCGGCGGCCGCCCTTTCCCACCGCCATTGCGGCGAGCGC
CGACGGGCAGCGGGCATGCG

Downstream 100 bases:

>100_bases
TCCGCGCGGGCGCATCACATGCGCCGCGCCCGCTCATCTTTCGACGCGGCGCGCGAATCGCTGCCCAGCCATCCCACTGA
TCGAGCCGATTTCATCGGCA

Product: putative hydroxyethylthioazole kinase

Products: NA

Alternate protein names: 4-methyl-5-beta-hydroxyethylthiazole kinase; TH kinase; Thz kinase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRKRTPSSARARANAIWNDTMESISWNTPSVRDALAAVKRDAPFIYGLTNYVAANLSANVLLAVGAAPAIGAAADWPARF
GAGANALWINTAALMSSGADTLLTAARAASKAGTRWVLDPVALGAGAPEYDAIVRDLLALRPTVIRGNASELIALAGGTA
AGKGVDTTASPESALAFIGDLARRSGAVVSVSGPTDYVTDGVATLAVAGGDARLTRVTGAGCALGALIAALLAQRGAALA
AASAAHAIYATAAERAADARGTASFAVRFVDELSLLDPAESSRDRSAGQIGAKRRE

Sequences:

>Translated_296_residues
MRKRTPSSARARANAIWNDTMESISWNTPSVRDALAAVKRDAPFIYGLTNYVAANLSANVLLAVGAAPAIGAAADWPARF
GAGANALWINTAALMSSGADTLLTAARAASKAGTRWVLDPVALGAGAPEYDAIVRDLLALRPTVIRGNASELIALAGGTA
AGKGVDTTASPESALAFIGDLARRSGAVVSVSGPTDYVTDGVATLAVAGGDARLTRVTGAGCALGALIAALLAQRGAALA
AASAAHAIYATAAERAADARGTASFAVRFVDELSLLDPAESSRDRSAGQIGAKRRE
>Mature_296_residues
MRKRTPSSARARANAIWNDTMESISWNTPSVRDALAAVKRDAPFIYGLTNYVAANLSANVLLAVGAAPAIGAAADWPARF
GAGANALWINTAALMSSGADTLLTAARAASKAGTRWVLDPVALGAGAPEYDAIVRDLLALRPTVIRGNASELIALAGGTA
AGKGVDTTASPESALAFIGDLARRSGAVVSVSGPTDYVTDGVATLAVAGGDARLTRVTGAGCALGALIAALLAQRGAALA
AASAAHAIYATAAERAADARGTASFAVRFVDELSLLDPAESSRDRSAGQIGAKRRE

Specific function: Thiamine biosynthesis. [C]

COG id: COG2145

COG function: function code H; Hydroxyethylthiazole kinase, sugar kinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Thz kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788421, Length=243, Percent_Identity=40.7407407407407, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000417 [H]

Pfam domain/function: PF02110 HK [H]

EC number: =2.7.1.50 [H]

Molecular weight: Translated: 29825; Mature: 29825

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRTPSSARARANAIWNDTMESISWNTPSVRDALAAVKRDAPFIYGLTNYVAANLSANV
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCE
LLAVGAAPAIGAAADWPARFGAGANALWINTAALMSSGADTLLTAARAASKAGTRWVLDP
EEEECCCCCCCCCCCCCHHHCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEECH
VALGAGAPEYDAIVRDLLALRPTVIRGNASELIALAGGTAAGKGVDTTASPESALAFIGD
HHHCCCCCHHHHHHHHHHHHCCEEEECCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHH
LARRSGAVVSVSGPTDYVTDGVATLAVAGGDARLTRVTGAGCALGALIAALLAQRGAALA
HHHHCCCEEEECCCCHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCHHH
AASAAHAIYATAAERAADARGTASFAVRFVDELSLLDPAESSRDRSAGQIGAKRRE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MRKRTPSSARARANAIWNDTMESISWNTPSVRDALAAVKRDAPFIYGLTNYVAANLSANV
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHCCCCCE
LLAVGAAPAIGAAADWPARFGAGANALWINTAALMSSGADTLLTAARAASKAGTRWVLDP
EEEECCCCCCCCCCCCCHHHCCCCCEEEEEHHHHHHCCHHHHHHHHHHHHHCCCEEEECH
VALGAGAPEYDAIVRDLLALRPTVIRGNASELIALAGGTAAGKGVDTTASPESALAFIGD
HHHCCCCCHHHHHHHHHHHHCCEEEECCHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHH
LARRSGAVVSVSGPTDYVTDGVATLAVAGGDARLTRVTGAGCALGALIAALLAQRGAALA
HHHHCCCEEEECCCCHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCHHH
AASAAHAIYATAAERAADARGTASFAVRFVDELSLLDPAESSRDRSAGQIGAKRRE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA