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The map label for this gene is nahR [H]

Identifier: 76819206

GI number: 76819206

Start: 1207368

End: 1208294

Strand: Direct

Name: nahR [H]

Synonym: BURPS1710b_A0948

Alternate gene names: 76819206

Gene position: 1207368-1208294 (Clockwise)

Preceding gene: 76817338

Following gene: 76818749

Centisome position: 37.95

GC content: 72.28

Gene sequence:

>927_bases
ATGCAGCCAGACCACCGACTCGACCTGAACCTGTTCCGCGTACTCGACGCGGTCTACGTGCAAGGCGGCATCAGCGCCGC
CGCCCGCGCGCTGCATCTGACGCAGCCTGCCGTCACCCATGCGCTGAACCGGCTGCGCGCGCATTTCGGCGATCCGCTCT
TCGTGCGACAGGGCAACAAGGTCGTGCCGACCGAGCGCACGCGCGAGGTGATCGCCGACGTCCAGCGCCATCTGAAGGGG
CTGCAGGATGCGGCGCGCGCGCAGACCCGCTTCAGCCCCGGCGCGCTCGACATGAGCTTCGTCGTCGGCGTGCGCGACGT
GCTCGAATCGATCGCGCTGCCGCAGCTCGTCGAGACGCTCGCGCGCGAAGCGCCCGGCGTGCGGCTCGTGAGCCGCCGCG
TGCCGGTTGCCGACATCGGGCGCGAGCTCGGCAGCGGCAATCTCGATCTCGCGATCGAGCGCCGCGTGCCCGCCGGGCCC
CGAATCGCCGCCGAACACGTGGCGGACGACACGCTCGTCGTCGCGATGCGGCGCGACCATGCGCTCGCGGGCGCGCCGCT
GCGCCGCGCCGACTACTTCGCCGCGGGACACGTGACGGTGTCGCCGCTCGGCGAGCCGCACACGCTCGACGTGCTGCTCG
GCGCCGACGGGCGCTTCCGGCGGATCCAGCTCGTCTGCCAGCACTACTTCGCCGCGTGCCAGATCGTGGCGTCGGGCGAT
CTGCTGCTGACGCTGCCGCGCTCCTACGCGCTGCGGATGACGCGGCTCCTGCCGCTCGCGGCGCAGCCGTTGCCGCTGCG
GCTCAAGCCGTATCCGATCCTCGCGTACTGGCACGAGTCGCGCGAGCTCGACCGCGCGCATCAGTGGTTCCGGCAACGCG
TGATCGAAGTCGTGCGCGCCGCGTCGCCGCATCCCGCGGGCGCATAG

Upstream 100 bases:

>100_bases
AACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAACGCCAAAC
GCAGGAACACCAAAACGCCG

Downstream 100 bases:

>100_bases
GCGCCGCTGCAGGCGCGCGCGAAGCCGTTTATGCTCGACCAGACGCGACCGGCGTGCCGGCCGCTTCCTCCCCTTACCTC
GAGAACACGCCATGCCGCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQPDHRLDLNLFRVLDAVYVQGGISAAARALHLTQPAVTHALNRLRAHFGDPLFVRQGNKVVPTERTREVIADVQRHLKG
LQDAARAQTRFSPGALDMSFVVGVRDVLESIALPQLVETLAREAPGVRLVSRRVPVADIGRELGSGNLDLAIERRVPAGP
RIAAEHVADDTLVVAMRRDHALAGAPLRRADYFAAGHVTVSPLGEPHTLDVLLGADGRFRRIQLVCQHYFAACQIVASGD
LLLTLPRSYALRMTRLLPLAAQPLPLRLKPYPILAYWHESRELDRAHQWFRQRVIEVVRAASPHPAGA

Sequences:

>Translated_308_residues
MQPDHRLDLNLFRVLDAVYVQGGISAAARALHLTQPAVTHALNRLRAHFGDPLFVRQGNKVVPTERTREVIADVQRHLKG
LQDAARAQTRFSPGALDMSFVVGVRDVLESIALPQLVETLAREAPGVRLVSRRVPVADIGRELGSGNLDLAIERRVPAGP
RIAAEHVADDTLVVAMRRDHALAGAPLRRADYFAAGHVTVSPLGEPHTLDVLLGADGRFRRIQLVCQHYFAACQIVASGD
LLLTLPRSYALRMTRLLPLAAQPLPLRLKPYPILAYWHESRELDRAHQWFRQRVIEVVRAASPHPAGA
>Mature_308_residues
MQPDHRLDLNLFRVLDAVYVQGGISAAARALHLTQPAVTHALNRLRAHFGDPLFVRQGNKVVPTERTREVIADVQRHLKG
LQDAARAQTRFSPGALDMSFVVGVRDVLESIALPQLVETLAREAPGVRLVSRRVPVADIGRELGSGNLDLAIERRVPAGP
RIAAEHVADDTLVVAMRRDHALAGAPLRRADYFAAGHVTVSPLGEPHTLDVLLGADGRFRRIQLVCQHYFAACQIVASGD
LLLTLPRSYALRMTRLLPLAAQPLPLRLKPYPILAYWHESRELDRAHQWFRQRVIEVVRAASPHPAGA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=298, Percent_Identity=25.1677852348993, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87081766, Length=268, Percent_Identity=24.6268656716418, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786820, Length=97, Percent_Identity=32.9896907216495, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34011; Mature: 34011

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPDHRLDLNLFRVLDAVYVQGGISAAARALHLTQPAVTHALNRLRAHFGDPLFVRQGNK
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCE
VVPTERTREVIADVQRHLKGLQDAARAQTRFSPGALDMSFVVGVRDVLESIALPQLVETL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AREAPGVRLVSRRVPVADIGRELGSGNLDLAIERRVPAGPRIAAEHVADDTLVVAMRRDH
HHHCCCCEEHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCEEEEEEECCC
ALAGAPLRRADYFAAGHVTVSPLGEPHTLDVLLGADGRFRRIQLVCQHYFAACQIVASGD
CCCCCCCHHHCEEEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCC
LLLTLPRSYALRMTRLLPLAAQPLPLRLKPYPILAYWHESRELDRAHQWFRQRVIEVVRA
EEEECCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ASPHPAGA
CCCCCCCC
>Mature Secondary Structure
MQPDHRLDLNLFRVLDAVYVQGGISAAARALHLTQPAVTHALNRLRAHFGDPLFVRQGNK
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCE
VVPTERTREVIADVQRHLKGLQDAARAQTRFSPGALDMSFVVGVRDVLESIALPQLVETL
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AREAPGVRLVSRRVPVADIGRELGSGNLDLAIERRVPAGPRIAAEHVADDTLVVAMRRDH
HHHCCCCEEHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCEEEEEEECCC
ALAGAPLRRADYFAAGHVTVSPLGEPHTLDVLLGADGRFRRIQLVCQHYFAACQIVASGD
CCCCCCCHHHCEEEECCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEECCC
LLLTLPRSYALRMTRLLPLAAQPLPLRLKPYPILAYWHESRELDRAHQWFRQRVIEVVRA
EEEECCHHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHH
ASPHPAGA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]