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The map label for this gene is cueR [H]

Identifier: 76819060

GI number: 76819060

Start: 2329654

End: 2330058

Strand: Direct

Name: cueR [H]

Synonym: BURPS1710b_A1913

Alternate gene names: 76819060

Gene position: 2329654-2330058 (Clockwise)

Preceding gene: 76817547

Following gene: 76818664

Centisome position: 73.22

GC content: 58.77

Gene sequence:

>405_bases
GTGAATATCGGCGAGGCTGCAAAGGTATCGGGCGTTAGCGCGAAGATGATTCGCTACTACGAGAGCGTGGGGCTTCTCAA
TCCCGCGAAGCGGACCGATTCTGGATACCGTGTCTATCACGACGACGAAATCCACTTGCTTCGCTTCATTCGGCAGGCTC
GGCGGCTCGGATTTCTCGTCGACGACATCAGGAAACTGCTCGCACTCTGGCAGGATCGCTCGAGAGCAAGCGCCGAAGTC
AAGGCGATCGCGCTCGAACACGTGGCTGAGCTCGACGGCCGGATTGCGGAGCTTACGGATATGCGGAACACGCTTGTGAA
CCTCGCCGCCCATTGCAGCGGGGACGATCGTCCAGACTGCCCCATTCTGGAGCGTTTGGCAGACCCATGCTGTGATCCAA
AGTAG

Upstream 100 bases:

>100_bases
CATGAGCTCAATGTTGGCATCGCCGTAGCCGGCCAAACCAAGGGGCCGTTTCGCGAGAACGCGCTAACATTTGGCTCTTC
GATTCAGTCTGGAGCACATC

Downstream 100 bases:

>100_bases
TGCATGCAAAGGTACGGGACGTCTGCGGTAAAACTGCGGAAGTACCCGAAAAATCAGACGGTTAAGTCGAGTTTGTTTGA
TCTATTCCAAGCTGGCATGC

Product: Cu(I)-responsive transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MNIGEAAKVSGVSAKMIRYYESVGLLNPAKRTDSGYRVYHDDEIHLLRFIRQARRLGFLVDDIRKLLALWQDRSRASAEV
KAIALEHVAELDGRIAELTDMRNTLVNLAAHCSGDDRPDCPILERLADPCCDPK

Sequences:

>Translated_134_residues
MNIGEAAKVSGVSAKMIRYYESVGLLNPAKRTDSGYRVYHDDEIHLLRFIRQARRLGFLVDDIRKLLALWQDRSRASAEV
KAIALEHVAELDGRIAELTDMRNTLVNLAAHCSGDDRPDCPILERLADPCCDPK
>Mature_134_residues
MNIGEAAKVSGVSAKMIRYYESVGLLNPAKRTDSGYRVYHDDEIHLLRFIRQARRLGFLVDDIRKLLALWQDRSRASAEV
KAIALEHVAELDGRIAELTDMRNTLVNLAAHCSGDDRPDCPILERLADPCCDPK

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=131, Percent_Identity=45.0381679389313, Blast_Score=122, Evalue=8e-30,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=39.3700787401575, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15076; Mature: 15076

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEAAKVSGVSAKMIRYYESVGLLNPAKRTDSGYRVYHDDEIHLLRFIRQARRLGFLV
CCCCCCHHHCCHHHHHHHHHHHHCCCCCHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
DDIRKLLALWQDRSRASAEVKAIALEHVAELDGRIAELTDMRNTLVNLAAHCSGDDRPDC
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PILERLADPCCDPK
HHHHHHHCCCCCCC
>Mature Secondary Structure
MNIGEAAKVSGVSAKMIRYYESVGLLNPAKRTDSGYRVYHDDEIHLLRFIRQARRLGFLV
CCCCCCHHHCCHHHHHHHHHHHHCCCCCHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
DDIRKLLALWQDRSRASAEVKAIALEHVAELDGRIAELTDMRNTLVNLAAHCSGDDRPDC
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PILERLADPCCDPK
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]