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The map label for this gene is ceoA [H]

Identifier: 76818881

GI number: 76818881

Start: 2229640

End: 2230869

Strand: Direct

Name: ceoA [H]

Synonym: BURPS1710b_A1840

Alternate gene names: 76818881

Gene position: 2229640-2230869 (Clockwise)

Preceding gene: 76818851

Following gene: 76817383

Centisome position: 70.08

GC content: 71.06

Gene sequence:

>1230_bases
ATGGCTATCTTGCGTACTTCCCGTTCGCGGATCGCGGCCGCGGCGTTCGCGGTCGTCTTCATCGCGGGCCTCGGCACGTT
CGGCGCGATCCGCGTGAATGCCGGCGCGCCGGAGAAATCGGCGGCGCCGCTGCCGGAGGTCGACGTCGCGACCGTGCTGT
CGAAGACGATCACCGATTGGCAGTCCTACTCGGGCCGCCTCGAGGCGGTCGAGAAGGTCGACGTGCGCCCGCTCGTGTCC
GGCACGATCGTGTCGGTGAATTTCAAGGACGGCGCGCTCGTGAAGAAGGGCGACGTGCTGTTCGTGATCGATCCGCGCCC
GTATCAGGCCGAGGTCGATCGCGCGGCCGCGCAGCTCGCCGGCGCGCAGGCCCGCAATGGCTACGCACAGAGCGACTGGC
AGCGCGCGCAGCGGCTGATCGGCGACAACGCGATCGCCAAGCGCGATTACGACGAGAAGCAGAACGCCGCGCGCGAGGCC
TCGGCGAACCTGAAGGCGGCTGAGGCCGCGCTCGAGACGGCGCGCATCAACCTCGGCTACACGCGGATCACCGCGCCCGT
GTCGGGCCGCGTGTCGCGCGCGGAGATCACGCTCGGCAACGTCGTGTCGGCGGGCGCGTCGGCCGCGCCGCTCACGACGC
TCGTGTCGGTGTCGCCGATCTACGCGTCGTTCGACGCGGACGAGCAGACTTACCTGCAATACATCGGCGGCGCGAAGGAC
GGCCGCAAGGTGCCCGTCGAGCTCGGCCTCGCGAACGAGAGCGGCTACTCGCGGCAGGGCGTGATCGATTCGGTCGACAA
CCGGCTCGATACGTCGTCGGGCACGATCCGCGTGCGCGCGCGCTTCGACAACGCGGACGGCGCGCTCGTGCCCGGCCTCT
ACGCGCGCGTGAAGGTGGGCGGCAGCGCGCCGCATCCGGCGCTGCTCATCGACGACGCGGCGATCAACACCGATCAGGAC
AAGAAGTTCGTGTTCGTCGTCGATCAGCAGGGCCGCGTGTCGTATCGCGAGGTGCAGCTCGGCGCGCAGCACGGCAACCA
GCGCGTGATCGTGGGCGGCCTGGCGGCGAGCGAGCGCATCGTCGTGAACGGCACGCAGCGCGTGCGGCCGGGCGAGCAGG
TGAAGCCGCATCTCGTGCCGATGACGGGCGGCGACGACGCTGCCGCCGCGACGCCCGTCGCGGGCGGCGTGCAGCGTCCG
CGGGCCGCGCAGGGCAACGCGCGCGCGTGA

Upstream 100 bases:

>100_bases
GAGGTGGCGCGTTTCTTCCAGTTCCGCTTCAGCGCGGGTGCACCGGGCTGACGCCGTTTTCATCCGAATTCAGAACAACC
GACAACCTGGGGGTTTTTTC

Downstream 100 bases:

>100_bases
CGCCCGAACGCTCCCGACGAGCGTTCGCCGCGCCAGCGCGCCCAATCAGACAGAGCCTTTCATGAACATATCGAAATTCT
TCATCGATCGACCGATCTTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MAILRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVS
GTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREA
SANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKD
GRKVPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQD
KKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRP
RAAQGNARA

Sequences:

>Translated_409_residues
MAILRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVS
GTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREA
SANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKD
GRKVPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQD
KKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRP
RAAQGNARA
>Mature_408_residues
AILRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDWQSYSGRLEAVEKVDVRPLVSG
TIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLAGAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREAS
ANLKAAEAALETARINLGYTRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKDG
RKVPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVGGSAPHPALLIDDAAINTDQDK
KFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERIVVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPR
AAQGNARA

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=341, Percent_Identity=33.1378299120235, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI87082036, Length=335, Percent_Identity=30.7462686567164, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786668, Length=381, Percent_Identity=32.8083989501312, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789665, Length=351, Percent_Identity=32.1937321937322, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI87081796, Length=375, Percent_Identity=27.7333333333333, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081951, Length=230, Percent_Identity=31.7391304347826, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789637, Length=139, Percent_Identity=33.0935251798561, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790519, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43036; Mature: 42905

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDW
CCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QSYSGRLEAVEKVDVRPLVSGTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLA
HHCCCHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHH
GAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASANLKAAEAALETARINLGY
CCHHCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEECCE
TRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKD
EEEECCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHCCCCC
GRKVPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVG
CCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEC
GSAPHPALLIDDAAINTDQDKKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERI
CCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCEEEEEECCCCCEE
VVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAAQGNARA
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AILRTSRSRIAAAAFAVVFIAGLGTFGAIRVNAGAPEKSAAPLPEVDVATVLSKTITDW
CEEECCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
QSYSGRLEAVEKVDVRPLVSGTIVSVNFKDGALVKKGDVLFVIDPRPYQAEVDRAAAQLA
HHCCCHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCEEEEECCCCCHHHHHHHHHHHH
GAQARNGYAQSDWQRAQRLIGDNAIAKRDYDEKQNAAREASANLKAAEAALETARINLGY
CCHHCCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEECCE
TRITAPVSGRVSRAEITLGNVVSAGASAAPLTTLVSVSPIYASFDADEQTYLQYIGGAKD
EEEECCCCCCCEEEEEEECHHHHCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHCCCCC
GRKVPVELGLANESGYSRQGVIDSVDNRLDTSSGTIRVRARFDNADGALVPGLYARVKVG
CCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEC
GSAPHPALLIDDAAINTDQDKKFVFVVDQQGRVSYREVQLGAQHGNQRVIVGGLAASERI
CCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCEEEEEEEHHCCCCCEEEEEECCCCCEE
VVNGTQRVRPGEQVKPHLVPMTGGDDAAAATPVAGGVQRPRAAQGNARA
EEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]