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The map label for this gene is pcaI [H]

Identifier: 76818849

GI number: 76818849

Start: 1881787

End: 1882500

Strand: Direct

Name: pcaI [H]

Synonym: BURPS1710b_A1552

Alternate gene names: 76818849

Gene position: 1881787-1882500 (Clockwise)

Preceding gene: 76818936

Following gene: 76817759

Centisome position: 59.14

GC content: 67.37

Gene sequence:

>714_bases
ATGGTCAACAAGATTTTCGATTCCCTCCAGTCGGCGGTGGCCGACGTCCACGACGGCGCGACGATCATGATCGGCGGCTT
CGGCACGGCCGGGATGCCCGCCGAGCTGATCGATGCGCTGATCGCGCAGGGCGCGCGCGATCTGACGATCGTCAACAACA
ACGCCGGCAACGGCGAGACGGGCCTCGCCGCGCTGCTGAAGGCGAGGCGCGTGCGCAAGATCATCTGCTCGTTTCCGCGG
CAGGCCGATTCGCAGGTGTTCGACGCGCTGTATCGCGCGGGCGAGATCGAGCTCGAACTGGTACCGCAAGGCAACCTCGC
CGAGCGGATTCGCGCGGCGGGCGCCGGTATCGGCGGCTTCTTCTCGCCGACGGGCTACGGCACGAAGCTCGCCGAAGGCA
AGGAAACGCGCGTGATCGACGGCAAGCACTACGTGTTCGAGACGCCGATCCATGCGGATTTCGCGCTCGTGAAGGCGTAC
CGGGGCGACCGCTGGGGCAACCTCGTCTATCGGAAGACCGCGCGCAATTTCGGGCCGGTGATGGCGATGGCCGCGAAGAC
GTCGATCGTGCAGGTGTCGCAAGTCGTGCCGCTCGGCGCGCTGAATCCGGAACACATCGTGACGCCCGGCATCTTCGTGC
AGCGCATCGTCGAAGTGCCGCAAGCCGCGCATGCGGCCGAACTGGCGGCCGAGCGCGCGGCGAGCGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGATATTCGAACCAATCGGATCGTCGCGCGAAGCGCGCAGCCCTTCGCGCGAACGCGTGCCGCGGCGGGCGACGCGCGC
GGATTCGCATAGGAAGAGAC

Downstream 100 bases:

>100_bases
ATCCCCGAGGAGAACACGATGAAACGACTGACCCGCGACGACATGGCGAAGCGCGTCGCGCAAGACATCCCCGAAGGCGC
CTATGTGAACCTCGGCATCG

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAY
RGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA

Sequences:

>Translated_237_residues
MVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAY
RGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
>Mature_237_residues
MVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGETGLAALLKARRVRKIICSFPR
QADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGFFSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAY
RGDRWGNLVYRKTARNFGPVMAMAAKTSIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=234, Percent_Identity=42.7350427350427, Blast_Score=206, Evalue=2e-53,
Organism=Homo sapiens, GI11545841, Length=224, Percent_Identity=45.5357142857143, Blast_Score=192, Evalue=2e-49,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=43.9252336448598, Blast_Score=191, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=264, Percent_Identity=39.7727272727273, Blast_Score=193, Evalue=8e-50,
Organism=Drosophila melanogaster, GI21358325, Length=231, Percent_Identity=45.021645021645, Blast_Score=197, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24655794, Length=231, Percent_Identity=45.021645021645, Blast_Score=197, Evalue=6e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 25123; Mature: 25123

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRKIICSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCC
FSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPV
CCCCCCCCCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHH
MAMAAKTSIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
HHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKIFDSLQSAVADVHDGATIMIGGFGTAGMPAELIDALIAQGARDLTIVNNNAGNGET
CHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCHH
GLAALLKARRVRKIICSFPRQADSQVFDALYRAGEIELELVPQGNLAERIRAAGAGIGGF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCC
FSPTGYGTKLAEGKETRVIDGKHYVFETPIHADFALVKAYRGDRWGNLVYRKTARNFGPV
CCCCCCCCCCCCCCCCEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHH
MAMAAKTSIVQVSQVVPLGALNPEHIVTPGIFVQRIVEVPQAAHAAELAAERAASAA
HHHHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]