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The map label for this gene is aldH [H]

Identifier: 76818785

GI number: 76818785

Start: 1871734

End: 1873713

Strand: Direct

Name: aldH [H]

Synonym: BURPS1710b_A1541

Alternate gene names: 76818785

Gene position: 1871734-1873713 (Clockwise)

Preceding gene: 76818605

Following gene: 76819743

Centisome position: 58.83

GC content: 71.01

Gene sequence:

>1980_bases
GTGTGGCTGTTCGGCTTCAAGTCGATCGTTGCGCGAGCCCGCGCCGAAGCCGATATCCCGTCATGGGCCCTCAACCGGCG
GCTCGCGTTCGCGACGATTGCAATCCCGGCCGGGAATGCCGCGTGTTCGCATTCGTTTGCCGGACGGCGCGCATGCGCGC
AGGACATGGCGACCGGTGCGGGCACGCGTGCGCCGGTCGGGATGCGCGGCGCACGCGTTGCCGTCTGCCACGATAATGGA
ATGCATGCGCGCCGGGGCGGTGCGATCCGTCGAACCGGCCGGTCGCCTCGACTCGTTCAATTCGACCCATTCGACCCATT
CGACCCATTCGTCCGCAGGCGGCGCACGCCGCATCGCGAAGCGCACCGCCCGCGGCCAGGTTTCCAATTCGGAGGAAGCA
TGCAGATCACCGGCGAGATGTTGATTGGCGCGGCCGCGGTGCGCGGTAGCGAAGGCACGATGCGCGCTTACGCGCCGGCG
CAGGGCGTCGAGCTCGAGCCGACGTTCGGCGCGGGCGGTGCGGCCGACGTCGATCGCGCGTGCCGCCTCGCGAACGCCGC
TTTCGATCCCTTTCGTCAGGCGCCGCTCGAGACGCGCGCACGCTTTCTCGAGGCGATCGCCGAGCGCATCGTCGGGCTCG
GCGATCCATTGATCGAACGCGCGCACGCGGAATCGGCGCTGCCCGTCGCGCGGCTCGAAGGCGAGCGCGCGCGCACGGTC
GGTCAGCTCAGGCTCTTCGCGGCGATCGTGCGCGACGGCCGCTGGCTGAGCGCGACGCTCGATTCCGCGCAGCCCGAGCG
CAAGCCGCTGCCGCGCGCCGATCTGCGCTTGCAGAAGATTCCCGTCGGCCCGGTCGCGGTGTTCGGCGCGAGCAATTTCC
CGCTCGCGTTCTCGGTCGCGGGCGGCGACACCGCTTCGGCGTTCGCGGCCGGCTGCCCCGTCGTCGCGAAGGCGCACCCC
GCGCATCTCGGCACGTCGGAGCTCGTCGGGCGCGCGATCCGGCAGGCTGTCGCCGATTGCGGTTTGCACGAGGGCGTGTT
CTCGCTCGTCGTCGGCGCGGGCAACGCGATCGGCGAGGCGCTCGTCGCGCATCCCGCGATCAGGGCGGTCGGCTTCACCG
GCTCGCGCGCGGGCGGCCTTGCGCTGATGGGCGTTGCCGCGCGGCGGCACGAGCCGATTCCGGTCTTCGCGGAAATGAGC
AGCATCAATCCGTTCTTCGTGTTGCCCGGCGCGTTGCGCGCACGCGGTGCGCAAATCGCGCAAGGCTTCGTCGAATCGCT
GACGCTCGGCGTCGGGCAGTTCTGCACGAACCCGGGGCTCGTCGTCGCGCTCGAAGGGCCCGACCTGAAGGCGTTCGTCG
ACGCGGCCGCGCAGGCGCTCTCGCAAAAGGGCGCGCAGACGATGCTGACCTCGGGCATCGCGTCGTCTTACGAGAGCGCG
GTCGCGGCGCGCCGCGCGGCCGCGGGCGTCAGCGAGGTCGCGCGCGGCGTGCGCAGCGACGCGCGGAACGCCGCGTTGCC
CGCGCTCTTCACGACGACGCACACGCAGTTCGTCCAGAACCCGCAGCTCGAAGCCGAGATCTTCGGGCCGACGTCGCTCG
TCGTCGCGTGCCGCGACATCGACGAGATGATCGCGCTTGCCGAGCATGTCGAGGGGCAACTGAGCGCGACGCTGCATCTC
GAAGACGACGATGTCGATCTGGCGCGCAAACTGCTGCCGACGCTCGAGCGCCGCGCCGGCCGCATCGTCGCGAACGGCTA
TCCGACGGGCGTCGAGGTCGCGTACGCGATGGTGCACGGCGGGCCGTTTCCGGCGACGTCGGACCCGCGCAGCACATCGG
TGGGCGCGCTTGCGATCGAGCGCTTCCTGCGGCCCGTCTGCTATCAGGATTTGCCGGCGGCGTTGTTGCCCGAGGCGCTC
GCCGACGCGAATCCGCTCGGCCTCTGGCGCCTGCGCGACGGCCAACTCGGCAAGGCGTGA

Upstream 100 bases:

>100_bases
TCGGCCTGGACGAGGAGTCTTGCCGCGCGACGCCCCCGCGACTTGCGCGGGGAACCGCCGGCGACGTGCGTGATGGCGCC
GATCGATCGACACGCATGCC

Downstream 100 bases:

>100_bases
GCGCGATGAGCGAGATCGGCTCACGGCGTTATCCCGACCCCGCGGTGCGCGTGCTCGATCCGCGCTTCGGCGCGCTGCGG
CTGCCGTCGGCGTCCGTCGA

Product: aldehyde dehydrogenase (NADP) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MWLFGFKSIVARARAEADIPSWALNRRLAFATIAIPAGNAACSHSFAGRRACAQDMATGAGTRAPVGMRGARVAVCHDNG
MHARRGGAIRRTGRSPRLVQFDPFDPFDPFVRRRRTPHREAHRPRPGFQFGGSMQITGEMLIGAAAVRGSEGTMRAYAPA
QGVELEPTFGAGGAADVDRACRLANAAFDPFRQAPLETRARFLEAIAERIVGLGDPLIERAHAESALPVARLEGERARTV
GQLRLFAAIVRDGRWLSATLDSAQPERKPLPRADLRLQKIPVGPVAVFGASNFPLAFSVAGGDTASAFAAGCPVVAKAHP
AHLGTSELVGRAIRQAVADCGLHEGVFSLVVGAGNAIGEALVAHPAIRAVGFTGSRAGGLALMGVAARRHEPIPVFAEMS
SINPFFVLPGALRARGAQIAQGFVESLTLGVGQFCTNPGLVVALEGPDLKAFVDAAAQALSQKGAQTMLTSGIASSYESA
VAARRAAAGVSEVARGVRSDARNAALPALFTTTHTQFVQNPQLEAEIFGPTSLVVACRDIDEMIALAEHVEGQLSATLHL
EDDDVDLARKLLPTLERRAGRIVANGYPTGVEVAYAMVHGGPFPATSDPRSTSVGALAIERFLRPVCYQDLPAALLPEAL
ADANPLGLWRLRDGQLGKA

Sequences:

>Translated_659_residues
MWLFGFKSIVARARAEADIPSWALNRRLAFATIAIPAGNAACSHSFAGRRACAQDMATGAGTRAPVGMRGARVAVCHDNG
MHARRGGAIRRTGRSPRLVQFDPFDPFDPFVRRRRTPHREAHRPRPGFQFGGSMQITGEMLIGAAAVRGSEGTMRAYAPA
QGVELEPTFGAGGAADVDRACRLANAAFDPFRQAPLETRARFLEAIAERIVGLGDPLIERAHAESALPVARLEGERARTV
GQLRLFAAIVRDGRWLSATLDSAQPERKPLPRADLRLQKIPVGPVAVFGASNFPLAFSVAGGDTASAFAAGCPVVAKAHP
AHLGTSELVGRAIRQAVADCGLHEGVFSLVVGAGNAIGEALVAHPAIRAVGFTGSRAGGLALMGVAARRHEPIPVFAEMS
SINPFFVLPGALRARGAQIAQGFVESLTLGVGQFCTNPGLVVALEGPDLKAFVDAAAQALSQKGAQTMLTSGIASSYESA
VAARRAAAGVSEVARGVRSDARNAALPALFTTTHTQFVQNPQLEAEIFGPTSLVVACRDIDEMIALAEHVEGQLSATLHL
EDDDVDLARKLLPTLERRAGRIVANGYPTGVEVAYAMVHGGPFPATSDPRSTSVGALAIERFLRPVCYQDLPAALLPEAL
ADANPLGLWRLRDGQLGKA
>Mature_659_residues
MWLFGFKSIVARARAEADIPSWALNRRLAFATIAIPAGNAACSHSFAGRRACAQDMATGAGTRAPVGMRGARVAVCHDNG
MHARRGGAIRRTGRSPRLVQFDPFDPFDPFVRRRRTPHREAHRPRPGFQFGGSMQITGEMLIGAAAVRGSEGTMRAYAPA
QGVELEPTFGAGGAADVDRACRLANAAFDPFRQAPLETRARFLEAIAERIVGLGDPLIERAHAESALPVARLEGERARTV
GQLRLFAAIVRDGRWLSATLDSAQPERKPLPRADLRLQKIPVGPVAVFGASNFPLAFSVAGGDTASAFAAGCPVVAKAHP
AHLGTSELVGRAIRQAVADCGLHEGVFSLVVGAGNAIGEALVAHPAIRAVGFTGSRAGGLALMGVAARRHEPIPVFAEMS
SINPFFVLPGALRARGAQIAQGFVESLTLGVGQFCTNPGLVVALEGPDLKAFVDAAAQALSQKGAQTMLTSGIASSYESA
VAARRAAAGVSEVARGVRSDARNAALPALFTTTHTQFVQNPQLEAEIFGPTSLVVACRDIDEMIALAEHVEGQLSATLHL
EDDDVDLARKLLPTLERRAGRIVANGYPTGVEVAYAMVHGGPFPATSDPRSTSVGALAIERFLRPVCYQDLPAALLPEAL
ADANPLGLWRLRDGQLGKA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=426, Percent_Identity=24.8826291079812, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081896, Length=458, Percent_Identity=27.5109170305677, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788042, Length=484, Percent_Identity=26.8595041322314, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789015, Length=404, Percent_Identity=24.7524752475248, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133930964, Length=294, Percent_Identity=26.8707482993197, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 69352; Mature: 69352

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLFGFKSIVARARAEADIPSWALNRRLAFATIAIPAGNAACSHSFAGRRACAQDMATGA
CCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHCCC
GTRAPVGMRGARVAVCHDNGMHARRGGAIRRTGRSPRLVQFDPFDPFDPFVRRRRTPHRE
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCEEEECCCCCCCHHHHHCCCCCHH
AHRPRPGFQFGGSMQITGEMLIGAAAVRGSEGTMRAYAPAQGVELEPTFGAGGAADVDRA
HCCCCCCCCCCCCEEEEHHHHHHHHHEECCCCCEEEECCCCCCEECCCCCCCCCCCHHHH
CRLANAAFDPFRQAPLETRARFLEAIAERIVGLGDPLIERAHAESALPVARLEGERARTV
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHH
GQLRLFAAIVRDGRWLSATLDSAQPERKPLPRADLRLQKIPVGPVAVFGASNFPLAFSVA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHCCEEEECCCCCEEEECCCCCCEEEEEC
GGDTASAFAAGCPVVAKAHPAHLGTSELVGRAIRQAVADCGLHEGVFSLVVGAGNAIGEA
CCCCHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
LVAHPAIRAVGFTGSRAGGLALMGVAARRHEPIPVFAEMSSINPFFVLPGALRARGAQIA
HHHCHHHHEECCCCCCCCCCCEEEHHHHCCCCCEEEEHHCCCCCEEEECCHHHHHHHHHH
QGFVESLTLGVGQFCTNPGLVVALEGPDLKAFVDAAAQALSQKGAQTMLTSGIASSYESA
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAARRAAAGVSEVARGVRSDARNAALPALFTTTHTQFVQNPQLEAEIFGPTSLVVACRDI
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEHHHH
DEMIALAEHVEGQLSATLHLEDDDVDLARKLLPTLERRAGRIVANGYPTGVEVAYAMVHG
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHEEHEEEC
GPFPATSDPRSTSVGALAIERFLRPVCYQDLPAALLPEALADANPLGLWRLRDGQLGKA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MWLFGFKSIVARARAEADIPSWALNRRLAFATIAIPAGNAACSHSFAGRRACAQDMATGA
CCCCCHHHHHHHHHHCCCCCHHHHCCEEEEEEEEEECCCCHHCCCHHHHHHHHHHHHCCC
GTRAPVGMRGARVAVCHDNGMHARRGGAIRRTGRSPRLVQFDPFDPFDPFVRRRRTPHRE
CCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCCEEEECCCCCCCHHHHHCCCCCHH
AHRPRPGFQFGGSMQITGEMLIGAAAVRGSEGTMRAYAPAQGVELEPTFGAGGAADVDRA
HCCCCCCCCCCCCEEEEHHHHHHHHHEECCCCCEEEECCCCCCEECCCCCCCCCCCHHHH
CRLANAAFDPFRQAPLETRARFLEAIAERIVGLGDPLIERAHAESALPVARLEGERARTV
HHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCHHHHHH
GQLRLFAAIVRDGRWLSATLDSAQPERKPLPRADLRLQKIPVGPVAVFGASNFPLAFSVA
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHCCEEEECCCCCEEEECCCCCCEEEEEC
GGDTASAFAAGCPVVAKAHPAHLGTSELVGRAIRQAVADCGLHEGVFSLVVGAGNAIGEA
CCCCHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
LVAHPAIRAVGFTGSRAGGLALMGVAARRHEPIPVFAEMSSINPFFVLPGALRARGAQIA
HHHCHHHHEECCCCCCCCCCCEEEHHHHCCCCCEEEEHHCCCCCEEEECCHHHHHHHHHH
QGFVESLTLGVGQFCTNPGLVVALEGPDLKAFVDAAAQALSQKGAQTMLTSGIASSYESA
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VAARRAAAGVSEVARGVRSDARNAALPALFTTTHTQFVQNPQLEAEIFGPTSLVVACRDI
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEHHHH
DEMIALAEHVEGQLSATLHLEDDDVDLARKLLPTLERRAGRIVANGYPTGVEVAYAMVHG
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEECCCCCHHHHEEHEEEC
GPFPATSDPRSTSVGALAIERFLRPVCYQDLPAALLPEALADANPLGLWRLRDGQLGKA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]