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The map label for this gene is epsC [H]

Identifier: 76818654

GI number: 76818654

Start: 1414589

End: 1415803

Strand: Direct

Name: epsC [H]

Synonym: BURPS1710b_A1131

Alternate gene names: 76818654

Gene position: 1414589-1415803 (Clockwise)

Preceding gene: 76817733

Following gene: 76819191

Centisome position: 44.46

GC content: 68.31

Gene sequence:

>1215_bases
ATGAAGAAAATCCTGCTTGCGTTCGGCACTCGTCCCGAAGCCATCAAGATGGCGCCGCTCGTGCGCATGCTGCAGACGCG
AGCCGACGTCGACGCGCGCGTATGCGTGACCGCCCAGCACCGGCAGATGCTCGACCAGGTGCTTGCGCTGTTCGACATCG
CGCCCGCGTACGATCTGAACGTGATGCGGCAGAGCCAGACGCTCGCCGACGTGACGACGGGCATCCTTCAGACGATCGGC
GCCGTGTTCGACGATTTCGATCCGGACATCGTGCTCGTGCACGGCGATACGACGACGACGCTCGCCGTGAGCCTCGCCGC
GTTCTACCGCTATTTGCCGATCGGCCACGTCGAAGCGGGGCTGCGCAGCGGCGACATCTGGTCGCCGTGGCCCGAGGAGC
TGAACCGGCGCGTGACCGACGCGGTGTCGTCCTGGCATTTCGCGCCGACCGAGCGCGCGCAGCACAACCTGTTCAGCGAA
GGCGTGCCGACGCAAGGCGTGGTGCTGACCGGCAATACGGTGATCGACGCGCTGCAGGACGTGAAGCGCATGCTCGACGC
CGACGCACCGCTCGCGCGCGAAATCGCCGCGCAGTTTCCGTTTCTCGGCCACGACGAGCGCGTCGTGCTGATCACCGGCC
ATCGGCGCGAGAGCTTCGGCGAGCCGTTCGCGCATTTCTGCGACGCGCTGCGCACGCTCGCGCGCCGCTACCCGGGCGTG
CGCTTCGTCTATCCGCTGCATCTGAATCCGAACGTGCAGGGGCCCGCGCACGCGCTGCTCGACGGCCTGCCGAACGTCCA
TCTGATCGCGCCGCAGGAATATCTGTCGTTCGTGTTCCTGATGTCGCGCGCGCATTTCATCATCACCGATTCGGGCGGCA
TCCAGGAGGAAGGGCCCGCGCTCGGCAAGCCGGTGCTCGTCACGCGCGACACGACCGAGCGGCCGGAGGCGATCCAGGCC
GGCACCGCGCGGCTCGTCGGCACGGACACCGAGCGCATCGTCGGCGAGGCGTCGCGCCTCCTCGACGACGACGACGCATA
CGACGAGATGTCGCGCGCGACGAATCCGTACGGCGACGGCCATGCGAGCGAGCGAATCGCACACGCGCTGCTGAACATGC
CGCATGCGGCCGACACGGCCCGCTTCCCGCTCGCCGCGATCGAAGCGCCGTGCAACGCGCTCGCGCTCGGCCTGCGCGCG
CTGAGGTCCGCATGA

Upstream 100 bases:

>100_bases
GCACCGCCCGCGCGTCGCGCACTCGCGCATGGCGTCGCGCGTTCACCGCGCCGCGTGCCGTATCGACTGAAACAACCGTA
ACCGCGAATCGGGGACCCAG

Downstream 100 bases:

>100_bases
ACGTGATCGTCTGGCGGCACGCGGGCCGCGCGACATCTGCGCGAGCGCCCGGGCGGCCGGCGTGTGCGCCTGCGCGCGCG
GCGGCCATCCGGTGATCGGG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKKILLAFGTRPEAIKMAPLVRMLQTRADVDARVCVTAQHRQMLDQVLALFDIAPAYDLNVMRQSQTLADVTTGILQTIG
AVFDDFDPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAGLRSGDIWSPWPEELNRRVTDAVSSWHFAPTERAQHNLFSE
GVPTQGVVLTGNTVIDALQDVKRMLDADAPLAREIAAQFPFLGHDERVVLITGHRRESFGEPFAHFCDALRTLARRYPGV
RFVYPLHLNPNVQGPAHALLDGLPNVHLIAPQEYLSFVFLMSRAHFIITDSGGIQEEGPALGKPVLVTRDTTERPEAIQA
GTARLVGTDTERIVGEASRLLDDDDAYDEMSRATNPYGDGHASERIAHALLNMPHAADTARFPLAAIEAPCNALALGLRA
LRSA

Sequences:

>Translated_404_residues
MKKILLAFGTRPEAIKMAPLVRMLQTRADVDARVCVTAQHRQMLDQVLALFDIAPAYDLNVMRQSQTLADVTTGILQTIG
AVFDDFDPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAGLRSGDIWSPWPEELNRRVTDAVSSWHFAPTERAQHNLFSE
GVPTQGVVLTGNTVIDALQDVKRMLDADAPLAREIAAQFPFLGHDERVVLITGHRRESFGEPFAHFCDALRTLARRYPGV
RFVYPLHLNPNVQGPAHALLDGLPNVHLIAPQEYLSFVFLMSRAHFIITDSGGIQEEGPALGKPVLVTRDTTERPEAIQA
GTARLVGTDTERIVGEASRLLDDDDAYDEMSRATNPYGDGHASERIAHALLNMPHAADTARFPLAAIEAPCNALALGLRA
LRSA
>Mature_404_residues
MKKILLAFGTRPEAIKMAPLVRMLQTRADVDARVCVTAQHRQMLDQVLALFDIAPAYDLNVMRQSQTLADVTTGILQTIG
AVFDDFDPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAGLRSGDIWSPWPEELNRRVTDAVSSWHFAPTERAQHNLFSE
GVPTQGVVLTGNTVIDALQDVKRMLDADAPLAREIAAQFPFLGHDERVVLITGHRRESFGEPFAHFCDALRTLARRYPGV
RFVYPLHLNPNVQGPAHALLDGLPNVHLIAPQEYLSFVFLMSRAHFIITDSGGIQEEGPALGKPVLVTRDTTERPEAIQA
GTARLVGTDTERIVGEASRLLDDDDAYDEMSRATNPYGDGHASERIAHALLNMPHAADTARFPLAAIEAPCNALALGLRA
LRSA

Specific function: May be involved in synthesis of N- acetyltrideoxygalactose, a component of exopolysaccharide EPS I which functions as a virulence factor [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=370, Percent_Identity=57.8378378378378, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44301; Mature: 44301

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILLAFGTRPEAIKMAPLVRMLQTRADVDARVCVTAQHRQMLDQVLALFDIAPAYDLN
CCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHH
VMRQSQTLADVTTGILQTIGAVFDDFDPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHC
LRSGDIWSPWPEELNRRVTDAVSSWHFAPTERAQHNLFSEGVPTQGVVLTGNTVIDALQD
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHH
VKRMLDADAPLAREIAAQFPFLGHDERVVLITGHRRESFGEPFAHFCDALRTLARRYPGV
HHHHHCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCHHHHHHHHHHHHHHHCCCC
RFVYPLHLNPNVQGPAHALLDGLPNVHLIAPQEYLSFVFLMSRAHFIITDSGGIQEEGPA
EEEEEEECCCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
LGKPVLVTRDTTERPEAIQAGTARLVGTDTERIVGEASRLLDDDDAYDEMSRATNPYGDG
CCCCEEEECCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCC
HASERIAHALLNMPHAADTARFPLAAIEAPCNALALGLRALRSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILLAFGTRPEAIKMAPLVRMLQTRADVDARVCVTAQHRQMLDQVLALFDIAPAYDLN
CCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHH
VMRQSQTLADVTTGILQTIGAVFDDFDPDIVLVHGDTTTTLAVSLAAFYRYLPIGHVEAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHHHC
LRSGDIWSPWPEELNRRVTDAVSSWHFAPTERAQHNLFSEGVPTQGVVLTGNTVIDALQD
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHH
VKRMLDADAPLAREIAAQFPFLGHDERVVLITGHRRESFGEPFAHFCDALRTLARRYPGV
HHHHHCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCHHHHHHHHHHHHHHHCCCC
RFVYPLHLNPNVQGPAHALLDGLPNVHLIAPQEYLSFVFLMSRAHFIITDSGGIQEEGPA
EEEEEEECCCCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
LGKPVLVTRDTTERPEAIQAGTARLVGTDTERIVGEASRLLDDDDAYDEMSRATNPYGDG
CCCCEEEECCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCC
HASERIAHALLNMPHAADTARFPLAAIEAPCNALALGLRALRSA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]