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The map label for this gene is ychM [C]

Identifier: 76818527

GI number: 76818527

Start: 1738543

End: 1740375

Strand: Direct

Name: ychM [C]

Synonym: BURPS1710b_A1427

Alternate gene names: 76818527

Gene position: 1738543-1740375 (Clockwise)

Preceding gene: 76819010

Following gene: 76817768

Centisome position: 54.64

GC content: 73.27

Gene sequence:

>1833_bases
TTGACCGAACGCGAACGCGCCGCGCGCGGGCGCAACGACGCGCGGCGCGGCGGCGGCGATAGCGGCGGCGACGACGAGGC
GTGGCGGCGCTGGCTGCCGGGCATCGCGACGTTGCGCGCGTACCGGCGCGCGTGGCTCGCACGGGATCTGTACGCGGGCG
TCGCGCTGACCGCGGTGCTCGTGCCGGTCGGCATGAGCTACGCTCAGGCGGCGGGCCTGCCGGTCATCGCCGGCCTGAAC
GCGTCGATCGCCGCGCTCGTCGGCTACGCGATCTTCGGGCCAAGCAGGATCCTGGTGCTCGGCCCCGATTCGGCGCTCGC
CGCGCTGATCGCCGGCGCGATCGCGCCGCTCGCGCACGGCGAGCCCGCGCACGCGGTCGCGCTCGCGGCCGCGCTCGCGT
TGATGTCCGGCGGCTTTTGCGTGCTCGCCGGCCTGCTGAAGCTGGGCTTCGTCACCGATCTGCTGTCCAAGCCGATTCAA
TACGGCTATCTGAACGGGCTCGCGCTGACGCTGATCGCGAGCCAGCTGCCGAGCCTGCTCGGCACCGTGCCGCTCGGCGG
CACGTTCGTCGACCAGGTCGCGAGCCTCGCCGCCACCGTCGCGCAAGGCCGGATCGATTTCGCGTCGCTCGCGCTCGGCG
GCGGCTGTCTCGCCGGCATCGCGCTGCTGCGGCGCGTCGCGCCCGCGTGGCCGGGCATGCTGATCGCGGTCGCCGGCGCG
TCGATCGTCGCCGCGTGGCTCGGCGCGGCGCCGGACGCGGGCGGCGCACACGCGCATGTCGCCTACGCGCATGTCGCAAA
CGCGCATGTCGCCCTCGTCGGCTCGCTCGCCGGCACGCTGCCGCCGCTCGGCCTGCCGTCGATCTCGCTCGCCGACGCGA
GCCGGCTCATCGCCGGCGCGCTCGCGATCGCGATGGTGTCGGTCGCCGACATCAGCGTGCTGTCGCATGTGTTCGCGCAG
CACGACGGCAGCGAAACGGACCGCAATCAGGAACTGTGCGCGCTCGGCGCGGCGAACCTGCTCGCCGGCATGCTGCGCGG
CTGCGCCGTCAGCAGCAGCGCGTCGCGCACGCCCGTCGCGCTCGCGGCCGGCGCGCGCACGCAGTTGACGAGCCTCGTCG
CGGCCGCGTGCATCGCGCTGCTGCTCATCGCGCCGACGCTGCTCGCCCGCGTGCCGCTCGCGGCGCTCGCGGCCGTCGTC
GTCTATTCGGCGAACGCGCTCGTCGACGTGCGTGCGATCGTTCGGCTCTATCGCGTGCGCCGCGGCGAATGCGCCGTATC
GGTGCTCTGCTTCGCGGGCGTCGTGCTGCTCGGCGTCGTGCCGGGCATCCTGCTCGCCGTCGGGCTGTCGCTGCTGTCGT
TCGTCTGGCGCGCGTGGCACCCGTACGACGCGGTGCTCGGCCGCGTCGAGGGCATGCACGGCTATCACGACGTGTCGCGC
CACCCGGGCGCGGCCCTGACGCGCGGCCTCGTCGCGTTTCGCTGGGACGCGCCGCTGTTCCATGCGAACGCGACGATCTT
TCGCGATCACGTGCGCGACGCGATCGCCGAGGCCGACGCGCCGGTGCGCTGCGTCGTGATCGCCGCCGAACCGATCACCG
ATGTCGACGTCACCGCCGCCGACATGCTCGCGACGCTGCGCGACGAGCTCGCCGCGCGGCGGATCGCGCTGGTGTTCGCG
GAAATGAAGGGGCCGGTCAAGGACCGGTTGCGCACGTACGGGCTCTTCGAGAAGATCGGCGCCGATCATTTTTTTCCGAC
GGTGACGGACGCGATCGAGCATTTCACGCGGATGCGCAAGGACGTGGCGACCGCGCGGCGGGCGCGGCGTTAG

Upstream 100 bases:

>100_bases
CGCTGCTGCACGTCGATGCGCACCCGCAACTGCTGCTGCGCATCGGACGCGGCCCGGTCGTCGCGCATGCGCCACGGCGT
CCGCTGATGGACGTCGTGTC

Downstream 100 bases:

>100_bases
CGGCGTTCCGGCTGTTTTCGGGAGCGTGAGCGGTGCGCGCACGCGCGCCGGCGGCGAACGATCACGATCGCGCAACCGCT
CGCCTGCTCGGCAAGCAAGC

Product: ulfate transporter family protein

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRAYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLN
ASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQ
YGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGA
SIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQ
HDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVV
VYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSR
HPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFA
EMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR

Sequences:

>Translated_610_residues
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRAYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLN
ASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQ
YGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGA
SIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQ
HDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVV
VYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSR
HPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFA
EMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>Mature_609_residues
TERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRAYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNA
SIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQY
GYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGAS
IVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQH
DGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVV
YSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRH
PGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAE
MKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI94721259, Length=509, Percent_Identity=28.8801571709234, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI94721253, Length=509, Percent_Identity=28.8801571709234, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI94721255, Length=509, Percent_Identity=28.8801571709234, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI94721257, Length=509, Percent_Identity=28.8801571709234, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI45827800, Length=511, Percent_Identity=25.8317025440313, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI39752683, Length=511, Percent_Identity=25.8317025440313, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI262206105, Length=602, Percent_Identity=27.7408637873754, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI262206075, Length=602, Percent_Identity=27.7408637873754, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI262206069, Length=602, Percent_Identity=27.7408637873754, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI262206063, Length=602, Percent_Identity=27.7408637873754, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI47131207, Length=653, Percent_Identity=27.2588055130168, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI20336272, Length=653, Percent_Identity=27.2588055130168, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI4557535, Length=514, Percent_Identity=25.6809338521401, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI269784651, Length=509, Percent_Identity=25.147347740668, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI45827802, Length=457, Percent_Identity=26.2582056892779, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI4505697, Length=521, Percent_Identity=25.3358925143954, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI100913030, Length=525, Percent_Identity=22.8571428571429, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI16418413, Length=518, Percent_Identity=23.1660231660232, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI217272867, Length=518, Percent_Identity=23.1660231660232, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI16418457, Length=540, Percent_Identity=20.1851851851852, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI301601599, Length=540, Percent_Identity=20.1851851851852, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI65506789, Length=337, Percent_Identity=27.299703264095, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI87081859, Length=452, Percent_Identity=24.1150442477876, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562578, Length=640, Percent_Identity=23.59375, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI86564196, Length=640, Percent_Identity=23.125, Blast_Score=135, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI17566848, Length=560, Percent_Identity=25, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI86565215, Length=601, Percent_Identity=22.7953410981697, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193203292, Length=526, Percent_Identity=22.2433460076046, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17551690, Length=610, Percent_Identity=23.1147540983607, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI86564876, Length=545, Percent_Identity=21.4678899082569, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319771, Length=470, Percent_Identity=23.1914893617021, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323121, Length=162, Percent_Identity=33.9506172839506, Blast_Score=87, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6325260, Length=602, Percent_Identity=18.7707641196013, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24649801, Length=590, Percent_Identity=24.7457627118644, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24651449, Length=574, Percent_Identity=22.9965156794425, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI85815873, Length=585, Percent_Identity=23.7606837606838, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21358633, Length=560, Percent_Identity=23.75, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24666186, Length=693, Percent_Identity=22.6551226551227, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19922482, Length=549, Percent_Identity=22.7686703096539, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21358229, Length=587, Percent_Identity=24.190800681431, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24647160, Length=618, Percent_Identity=21.3592233009709, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21355087, Length=618, Percent_Identity=21.3592233009709, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24663084, Length=609, Percent_Identity=25.4515599343186, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357695, Length=609, Percent_Identity=25.4515599343186, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 63084; Mature: 62953

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRAYRRAWLARDLYAGVALTAVL
CCCHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHG
HHHCHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCC
EPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
SIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHC
HPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAA
CCCHHHHHCHHEEEECCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
DMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
DVATARRARR
HHHHHHHCCC
>Mature Secondary Structure 
TERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRAYRRAWLARDLYAGVALTAVL
CCHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHG
HHHCHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCC
EPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHH
SIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHC
HPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAA
CCCHHHHHCHHEEEECCCEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHH
DMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRK
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
DVATARRARR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]