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The map label for this gene is prgH [H]

Identifier: 76818491

GI number: 76818491

Start: 781455

End: 782741

Strand: Direct

Name: prgH [H]

Synonym: BURPS1710b_A0589

Alternate gene names: 76818491

Gene position: 781455-782741 (Clockwise)

Preceding gene: 76818781

Following gene: 76817887

Centisome position: 24.56

GC content: 69.93

Gene sequence:

>1287_bases
ATGAATAAACCAGATTCCGGACTTGAAGCTCTGCAACTCCGAATCCTGTTCGGTCCGCTATTCGGCTCGGATATCGCGAT
TCCGTCAGGGGAAGTATTTTTCTGCGTCGGCGAGCAGGTGATCGACGATCGTCCGGCGGAGCATCCGGAAAATCGCGCCG
GCCATTTACTGGAGCGCGCGGTCGATACGCTGTATATCCCGCACCGGGCCGGCGCGCCGAATTTCCGCCTGCGTTTTCCG
GGCGCGCCGACGCAGGCGGCGCGAACCGCCGAAACCGGCGAAGCCGCGCCCGGCGATTTCGAAGTCGATTTTCTGTCGGC
GGACGGTTGCGTCACGCAACGCGCGGCATTCAACACCGTCTGCCGCTTCGGCGATCTCGCGTTCGCGCTCAGGCGTCAGC
GCGAGCCATGGAGCGAGGCGGTCATGCACTACGCGCCGCACGCGCCTTCGCGTGCGGCGGACGCCGCCGAGCCGGGCGCG
CCCGGTGAGCCCGGCGATGGCGGCGAGCGCGCATCGCGCTTCGCGCTGAAGCTCGGCGCGCTGCTCGTCGCGGGGGTCGC
GCTCGCGGCGCTCGCGTACTGGCAGGTGCAGCGCTATGTCGGCGCGCAGAAGCTCGCGAGCGTCAACGGCGTGCTGGCGG
GCGCGCCCGTGCCCAACGCGATCCTGCCCGGCGACGACGGCCGGATCTACGTGCTGAGCGCATCGCAGGACGGCGCCGAA
TGGGACCGCGAGGCGCTGCTGAAGGCGGCGCTGCCGGAGAAGATCGAAGTCGCCGTGATCGGCGCGGAGCGGCAACGCGT
CGAGCGCCGGCTCGACGAAGCCGGCGTCGATTTCGTGACCGTGCGCCTCGACGCGCCCGAGCACCCGGAGCTGATCCTCA
CCGGCGCCGCGCCCGCCGCCGCGCGCGCACGCGCGATCGGCGAGCTGCGGCGCGCGGCCCCGTACGTCCGGGACGTGCGC
GTGATCGACGCGAGCCTCGGCGCGATCGAGCAGGAGGCGCGCAACGCGCTCGACAAGGTGGGCGCGCGCTACCGGCTGCT
CGCGCGGCGCGGCGGCGCGACGTTCGAGGTGGCGAGCTCGTTCGGCGACGAGGAGCTCGCCGCCTTGCAGAACCTCATGC
GCTCGTTCGGCCACAAGTGGGGCACGCGCCGCGTCGATTTCAAGATCGCGCTGCGCACCGACTGGCTGAAGGGCAAATCG
TATCGGGAAGGCGGCGACGGCTACGTGCTGCTCGATCACGCGTCCTGGTATTTCCCGCAACCCCTGGAAGGAGCACATTA
CCGATGA

Upstream 100 bases:

>100_bases
ATTATCCGGTTCACGATCGACGGCAGCGAAGGCGATCGGGAAAACGATATATACATAATCAGGCCATTTATCGCCCAGGT
CACCCTGGAAAATTACCGAG

Downstream 100 bases:

>100_bases
GCAATCCCCCGACCCCGCTGCTGGCCGACTACGAGTGGTCAGGCTACCTGACCGGCATCGGCCGCGCGTTCGACGACGGC
GTGAAGGATCTGAACAAGCA

Product: type III secretion system protein PrgH/EprH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNKPDSGLEALQLRILFGPLFGSDIAIPSGEVFFCVGEQVIDDRPAEHPENRAGHLLERAVDTLYIPHRAGAPNFRLRFP
GAPTQAARTAETGEAAPGDFEVDFLSADGCVTQRAAFNTVCRFGDLAFALRRQREPWSEAVMHYAPHAPSRAADAAEPGA
PGEPGDGGERASRFALKLGALLVAGVALAALAYWQVQRYVGAQKLASVNGVLAGAPVPNAILPGDDGRIYVLSASQDGAE
WDREALLKAALPEKIEVAVIGAERQRVERRLDEAGVDFVTVRLDAPEHPELILTGAAPAAARARAIGELRRAAPYVRDVR
VIDASLGAIEQEARNALDKVGARYRLLARRGGATFEVASSFGDEELAALQNLMRSFGHKWGTRRVDFKIALRTDWLKGKS
YREGGDGYVLLDHASWYFPQPLEGAHYR

Sequences:

>Translated_428_residues
MNKPDSGLEALQLRILFGPLFGSDIAIPSGEVFFCVGEQVIDDRPAEHPENRAGHLLERAVDTLYIPHRAGAPNFRLRFP
GAPTQAARTAETGEAAPGDFEVDFLSADGCVTQRAAFNTVCRFGDLAFALRRQREPWSEAVMHYAPHAPSRAADAAEPGA
PGEPGDGGERASRFALKLGALLVAGVALAALAYWQVQRYVGAQKLASVNGVLAGAPVPNAILPGDDGRIYVLSASQDGAE
WDREALLKAALPEKIEVAVIGAERQRVERRLDEAGVDFVTVRLDAPEHPELILTGAAPAAARARAIGELRRAAPYVRDVR
VIDASLGAIEQEARNALDKVGARYRLLARRGGATFEVASSFGDEELAALQNLMRSFGHKWGTRRVDFKIALRTDWLKGKS
YREGGDGYVLLDHASWYFPQPLEGAHYR
>Mature_428_residues
MNKPDSGLEALQLRILFGPLFGSDIAIPSGEVFFCVGEQVIDDRPAEHPENRAGHLLERAVDTLYIPHRAGAPNFRLRFP
GAPTQAARTAETGEAAPGDFEVDFLSADGCVTQRAAFNTVCRFGDLAFALRRQREPWSEAVMHYAPHAPSRAADAAEPGA
PGEPGDGGERASRFALKLGALLVAGVALAALAYWQVQRYVGAQKLASVNGVLAGAPVPNAILPGDDGRIYVLSASQDGAE
WDREALLKAALPEKIEVAVIGAERQRVERRLDEAGVDFVTVRLDAPEHPELILTGAAPAAARARAIGELRRAAPYVRDVR
VIDASLGAIEQEARNALDKVGARYRLLARRGGATFEVASSFGDEELAALQNLMRSFGHKWGTRRVDFKIALRTDWLKGKS
YREGGDGYVLLDHASWYFPQPLEGAHYR

Specific function: Required for invasion of epithelial cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013387
- InterPro:   IPR019029 [H]

Pfam domain/function: PF09480 PrgH [H]

EC number: NA

Molecular weight: Translated: 46333; Mature: 46333

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPDSGLEALQLRILFGPLFGSDIAIPSGEVFFCVGEQVIDDRPAEHPENRAGHLLERA
CCCCCCCHHHHEEHEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHHHHHH
VDTLYIPHRAGAPNFRLRFPGAPTQAARTAETGEAAPGDFEVDFLSADGCVTQRAAFNTV
HHHEECCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
CRFGDLAFALRRQREPWSEAVMHYAPHAPSRAADAAEPGAPGEPGDGGERASRFALKLGA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LLVAGVALAALAYWQVQRYVGAQKLASVNGVLAGAPVPNAILPGDDGRIYVLSASQDGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEECCCCCCH
WDREALLKAALPEKIEVAVIGAERQRVERRLDEAGVDFVTVRLDAPEHPELILTGAAPAA
HHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHH
ARARAIGELRRAAPYVRDVRVIDASLGAIEQEARNALDKVGARYRLLARRGGATFEVASS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHHH
FGDEELAALQNLMRSFGHKWGTRRVDFKIALRTDWLKGKSYREGGDGYVLLDHASWYFPQ
CCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCC
PLEGAHYR
CCCCCCCC
>Mature Secondary Structure
MNKPDSGLEALQLRILFGPLFGSDIAIPSGEVFFCVGEQVIDDRPAEHPENRAGHLLERA
CCCCCCCHHHHEEHEEEECCCCCCCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHHHHHH
VDTLYIPHRAGAPNFRLRFPGAPTQAARTAETGEAAPGDFEVDFLSADGCVTQRAAFNTV
HHHEECCCCCCCCCEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHH
CRFGDLAFALRRQREPWSEAVMHYAPHAPSRAADAAEPGAPGEPGDGGERASRFALKLGA
HHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LLVAGVALAALAYWQVQRYVGAQKLASVNGVLAGAPVPNAILPGDDGRIYVLSASQDGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCEEEEEECCCCCCH
WDREALLKAALPEKIEVAVIGAERQRVERRLDEAGVDFVTVRLDAPEHPELILTGAAPAA
HHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECCCCHH
ARARAIGELRRAAPYVRDVRVIDASLGAIEQEARNALDKVGARYRLLARRGGATFEVASS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEHHH
FGDEELAALQNLMRSFGHKWGTRRVDFKIALRTDWLKGKSYREGGDGYVLLDHASWYFPQ
CCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCC
PLEGAHYR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609 [H]