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The map label for this gene is nahR [H]

Identifier: 76818219

GI number: 76818219

Start: 1723845

End: 1724780

Strand: Direct

Name: nahR [H]

Synonym: BURPS1710b_A1414

Alternate gene names: 76818219

Gene position: 1723845-1724780 (Clockwise)

Preceding gene: 76817619

Following gene: 76818085

Centisome position: 54.18

GC content: 68.48

Gene sequence:

>936_bases
ATGATCCAGAATCTGCGACAGCTCGACCTGAACCTGCTGCTCGTGTTCGACGCGCTGATGCAGGAGCAGAACCTGTCGCG
CGCCGCCATCCGGCTGCACATGAGCCAGCCGGCCGTCAGCAATGCGCTGACGCGGCTGCGTCAGCAGCTCGGCGAGCCGC
TCTTCACGCGCACCGCGCGCGGCATGACGCCGACCGCGCAGGCGCGCACGCTGTACGAGCCGGTCCGCCAGGCGCTGTAT
CTGCTGCAGATCGGGCTCGGCCCGCAAGCCGATTTCGAGCCCGACACGCACCACCTGTTCAAGCTGTCGATGAACGATTA
CGGGCAAACGGTGCTGCTGCCCGATCTGCTCGCGCACATCAAGTCGCGCGCGCCGAACGTGATGCTCTCGGTGCAGAGCG
ACGACGCCGGCTCGATTCCCGCGCAACTGACGACGGGCACGCTCGATCTCGCGATCGACTACCTGCATTTCGACAATCCG
GAGCTCTGCTACGAGCCGCTGCACGAGGAGCACCTCGTCGTGATCGGGCGCGCCGGCCATCCGGCGTTCGCCGGCGGGCT
CGCGCTGCGCGGCTACGAGGAGAGCGGGCACGTGTCGATCCAGCCGCGCGACAGGCGCGGCTCGCCGCTCGAGATCGTGC
TCGGCTCCGCGCGCGTGCGGCGCGTCGTGCATCTGCAGGTGCCGCACTATCTGACGATTCCCGCGCTCGTCGCGAAATCG
GACCTGCTCGGCACGATCCCGCGCCGGCTCGCCGAGCGGTTCGCCGATGTCTATGCGCTGCAGATCGCGCCGCTGCCGAT
CGATATCGCGCCGATCCAGGTGAGCCTCATCTGGCATCGTCAGCAGGATGCGCAGCCCGGCCTGCGCTGGCTGCGCGAGC
AGGTCGTTCTCACGCATCGCGCGATCATCGGATGCGGCGAGCACGCGCCGGCGTGA

Upstream 100 bases:

>100_bases
CGCGCCCACCGTGCGCGCGCAAGCGTCGGGCGCGCGCGCATGCCCGCGCCGCCCTCGCGCATCCGGCGCGCCGCCTGCCC
CCATTCCGGAGCGCCGCCGT

Downstream 100 bases:

>100_bases
CAGGCGTCGTGCGAGATGTGCCGCGCGCGCGGCATCGGCCGCCAGGCGCGCGGCAACGCGACCGCGCCGTCGCCGATCGC
GGCCGCCGCGATCGGCGCGA

Product: LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALY
LLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNP
ELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKS
DLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA

Sequences:

>Translated_311_residues
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALY
LLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNP
ELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKS
DLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>Mature_311_residues
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALY
LLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNP
ELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKS
DLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=293, Percent_Identity=35.1535836177474, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87081766, Length=266, Percent_Identity=27.8195488721804, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790147, Length=301, Percent_Identity=24.5847176079734, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786820, Length=283, Percent_Identity=21.9081272084806, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=251, Percent_Identity=23.1075697211155, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=166, Percent_Identity=28.3132530120482, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34607; Mature: 34607

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTAR
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCC
GMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHH
KSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGH
HHCCCCEEEEEECCCCCCCCCEEECCCCEEEEEEEECCCHHHHHCCCCCCEEEEEECCCC
PAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKS
CCHHCCEEEECCCCCCEEEEEECCCCCCCEEEEECCHHHEEEEEEECCCEEEHHHHHHHH
DLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHR
HHHHHHHHHHHHHHHHEEEEEEECCCEEECEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AIIGCGEHAPA
HHEECCCCCCC
>Mature Secondary Structure
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTAR
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCC
GMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHI
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHH
KSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGH
HHCCCCEEEEEECCCCCCCCCEEECCCCEEEEEEEECCCHHHHHCCCCCCEEEEEECCCC
PAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKS
CCHHCCEEEECCCCCCEEEEEECCCCCCCEEEEECCHHHEEEEEEECCCEEEHHHHHHHH
DLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHR
HHHHHHHHHHHHHHHHEEEEEEECCCEEECEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AIIGCGEHAPA
HHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]