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The map label for this gene is 76818008

Identifier: 76818008

GI number: 76818008

Start: 1364465

End: 1365517

Strand: Direct

Name: 76818008

Synonym: BURPS1710b_A1091

Alternate gene names: NA

Gene position: 1364465-1365517 (Clockwise)

Preceding gene: 76818934

Following gene: 76819434

Centisome position: 42.88

GC content: 62.49

Gene sequence:

>1053_bases
ATGACTATCTCGCCGCGCGACGAACAGAATCGATCGGTCGATCTATGGTTCGCCTACAAAGTGCCGAAGCTCACGAAGGA
TACCGACAGCGACAGCGCAACCGGCTATGAATACGTGTATTACGATCGCGAAATCGGGTCGGTGCAGAAGTCGCCGAATC
GGATGAACAACCCGAAAGGGGCGCTGTTCTACACACTCGATTCGATCTTCGGCGATCCGGGCAGCACGACGGGCTGGATT
CTCTACAACGACGAAATGCCGGCCGATGCGGACCGTTCGAACAACGCGACGCTCGGCCATACGAAAGGCGTGATCGCCTT
CGACATCGCGTCGAACTCCGCCTTGTGGCTGCTGCACTCGTGGCCGAAATACACGAGCCCGTCGGCCCCCGGCGTGCCGA
CGCCGCTGTACGGGCAGACGTTCCTGTGTGTGAGCCTCGATCTCGAGACGGCAGGCAAGATCGCCGCGCAGATGGCGCTG
CATCAGCAGCCGCAGGTCTACCTGCCGCGCACCGCCGGGCTCGATCACGCGAGCCCGCTATACACGCTCACGCAGCCGCT
CAACGCGTCCGCGCCCGGCGATTCGGATTCGCTCGACTTCAAGACCCGCGGCGGCGCGCCGTTCAAGGTGATCGCGAAGA
ATCGCAAGTGGGGCAAGGATTTCTGGAACGATCTCGTCGGCCCGACGCTGAAGGCCGACATGGACGTCGAGACATGGATC
CGCGGCAAGATCCCGCCCATTCTCGACTCCGACGGCGTGCACAAGACCTACGACATCAAGTTCATCGATCTGCGCAAGCT
CGGCGCGCCATGGGCATGGCCCGAAACGCAGGACCATGCGAAATGGGGCATCACGACGACCGACGACTGGGTGTGCGTCG
GCGATATCAATCGAATGGTGACGCAGGAAAAACGCGGCGGCGGCACGATCGCCTTCCAGGATCCGCAATTGTGGAAGGCG
CTGTCGCAGACCGATCTGATCGTGCCGCCGCCCGGCAAGACCGAAGCGCAGGCGCGCGCGATGATCCATAGAACGCACCA
GCCGGCCGACTAG

Upstream 100 bases:

>100_bases
CCGCAACGGCAAACAACCGTCGACGACAAACAAGGACGCTTCGCCACCGCGGGCGTCGCTTGCCGCGCATGCGGCGCCAT
TCAGCAACCGGGGGCATCAC

Downstream 100 bases:

>100_bases
CGCGGCATCCGCCCGACGACACGACAAAACATCGACGCACGCGCGTCCCCACACCGCCCAGGAGTCTTGCCATGAATGCG
CATCTGCCCGCCGGCGCGCT

Product: putative deoxyribonuclease

Products: NA

Alternate protein names: Deoxyribonuclease II

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTISPRDEQNRSVDLWFAYKVPKLTKDTDSDSATGYEYVYYDREIGSVQKSPNRMNNPKGALFYTLDSIFGDPGSTTGWI
LYNDEMPADADRSNNATLGHTKGVIAFDIASNSALWLLHSWPKYTSPSAPGVPTPLYGQTFLCVSLDLETAGKIAAQMAL
HQQPQVYLPRTAGLDHASPLYTLTQPLNASAPGDSDSLDFKTRGGAPFKVIAKNRKWGKDFWNDLVGPTLKADMDVETWI
RGKIPPILDSDGVHKTYDIKFIDLRKLGAPWAWPETQDHAKWGITTTDDWVCVGDINRMVTQEKRGGGTIAFQDPQLWKA
LSQTDLIVPPPGKTEAQARAMIHRTHQPAD

Sequences:

>Translated_350_residues
MTISPRDEQNRSVDLWFAYKVPKLTKDTDSDSATGYEYVYYDREIGSVQKSPNRMNNPKGALFYTLDSIFGDPGSTTGWI
LYNDEMPADADRSNNATLGHTKGVIAFDIASNSALWLLHSWPKYTSPSAPGVPTPLYGQTFLCVSLDLETAGKIAAQMAL
HQQPQVYLPRTAGLDHASPLYTLTQPLNASAPGDSDSLDFKTRGGAPFKVIAKNRKWGKDFWNDLVGPTLKADMDVETWI
RGKIPPILDSDGVHKTYDIKFIDLRKLGAPWAWPETQDHAKWGITTTDDWVCVGDINRMVTQEKRGGGTIAFQDPQLWKA
LSQTDLIVPPPGKTEAQARAMIHRTHQPAD
>Mature_349_residues
TISPRDEQNRSVDLWFAYKVPKLTKDTDSDSATGYEYVYYDREIGSVQKSPNRMNNPKGALFYTLDSIFGDPGSTTGWIL
YNDEMPADADRSNNATLGHTKGVIAFDIASNSALWLLHSWPKYTSPSAPGVPTPLYGQTFLCVSLDLETAGKIAAQMALH
QQPQVYLPRTAGLDHASPLYTLTQPLNASAPGDSDSLDFKTRGGAPFKVIAKNRKWGKDFWNDLVGPTLKADMDVETWIR
GKIPPILDSDGVHKTYDIKFIDLRKLGAPWAWPETQDHAKWGITTTDDWVCVGDINRMVTQEKRGGGTIAFQDPQLWKAL
SQTDLIVPPPGKTEAQARAMIHRTHQPAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNase II family

Homologues:

Organism=Homo sapiens, GI4503349, Length=323, Percent_Identity=28.1733746130031, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI194473657, Length=338, Percent_Identity=28.698224852071, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI32564440, Length=355, Percent_Identity=29.5774647887324, Blast_Score=147, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17554078, Length=351, Percent_Identity=29.9145299145299, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17552978, Length=348, Percent_Identity=30.4597701149425, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17550236, Length=354, Percent_Identity=31.9209039548023, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21357117, Length=338, Percent_Identity=29.2899408284024, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNS2_BURP1 (Q3JJK4)

Other databases:

- EMBL:   CP000125
- RefSeq:   YP_336249.1
- STRING:   Q3JJK4
- GeneID:   3694325
- GenomeReviews:   CP000125_GR
- KEGG:   bpm:BURPS1710b_A1091
- TIGR:   BURPS1710b_A1091
- eggNOG:   NOG145330
- HOGENOM:   HBG042500
- OMA:   CVGDMNR
- ProtClustDB:   CLSK711179
- BioCyc:   BPSE320372:BURPS1710B_B1287-MONOMER
- InterPro:   IPR004947
- PANTHER:   PTHR10858

Pfam domain/function: PF03265 DNase_II

EC number: NA

Molecular weight: Translated: 38837; Mature: 38706

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPRDEQNRSVDLWFAYKVPKLTKDTDSDSATGYEYVYYDREIGSVQKSPNRMNNPKG
CCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCCCCCCCCC
ALFYTLDSIFGDPGSTTGWILYNDEMPADADRSNNATLGHTKGVIAFDIASNSALWLLHS
EEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEC
WPKYTSPSAPGVPTPLYGQTFLCVSLDLETAGKIAAQMALHQQPQVYLPRTAGLDHASPL
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
YTLTQPLNASAPGDSDSLDFKTRGGAPFKVIAKNRKWGKDFWNDLVGPTLKADMDVETWI
EEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCEECCCCHHHHH
RGKIPPILDSDGVHKTYDIKFIDLRKLGAPWAWPETQDHAKWGITTTDDWVCVGDINRMV
CCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
TQEKRGGGTIAFQDPQLWKALSQTDLIVPPPGKTEAQARAMIHRTHQPAD
HHHCCCCCEEEEECHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TISPRDEQNRSVDLWFAYKVPKLTKDTDSDSATGYEYVYYDREIGSVQKSPNRMNNPKG
CCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCCCCCCCCC
ALFYTLDSIFGDPGSTTGWILYNDEMPADADRSNNATLGHTKGVIAFDIASNSALWLLHS
EEEEEEHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEC
WPKYTSPSAPGVPTPLYGQTFLCVSLDLETAGKIAAQMALHQQPQVYLPRTAGLDHASPL
CCCCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
YTLTQPLNASAPGDSDSLDFKTRGGAPFKVIAKNRKWGKDFWNDLVGPTLKADMDVETWI
EEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCEECCCCHHHHH
RGKIPPILDSDGVHKTYDIKFIDLRKLGAPWAWPETQDHAKWGITTTDDWVCVGDINRMV
CCCCCCCCCCCCCCEEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
TQEKRGGGTIAFQDPQLWKALSQTDLIVPPPGKTEAQARAMIHRTHQPAD
HHHCCCCCEEEEECHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA