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The map label for this gene is icaB [H]

Identifier: 76817837

GI number: 76817837

Start: 1762568

End: 1763704

Strand: Direct

Name: icaB [H]

Synonym: BURPS1710b_A1448

Alternate gene names: 76817837

Gene position: 1762568-1763704 (Clockwise)

Preceding gene: 76819527

Following gene: 76819788

Centisome position: 55.4

GC content: 71.06

Gene sequence:

>1137_bases
GTGACGAGCGTGACGAGCGTGACGAGCGTGACGAGCGGGACGTGCGGGACGTGCGGGACGTGCGGGACGTGCGGGACGTG
CGGGACGTGCGCCATGCGCGTGACAGGCGCGGCGGCGCGACGCCCGGCAACTGCCATGCGTTGCGCCGCGAAGCGCACGT
CGCGCCGAGCATGGGAAAACACGCACCGTCCGCGCCGTCGCAACCGGTCGGCCCGAACACGTTTCGAACAACCCAAGGAA
CGGCCCTTGCGACATTCAGGCTCCCGGCTCACCCGATTCCGGCTCGCGGCGGCGGCCTGCTGTCTCGCATTGGCAAGCGC
CGCGCGCCCCGCGTTCGCCGGCGCGAACGCGCCTGCCGCCGCCGAGCCGCCCACCGATGCGCAGCGCCCCGCGATCCTCG
TCTATCACCGCTTCTCGACGTCCGCGCCGCCCGATTCGATGACCGTGCGCGTCAGCACGTTCGGCGCGCAGCTCGCGTTC
CTGCGCGCGCACGGTTACACGTTCGTGCCGCTGCGCGACGTCGTCGCGTGGGCGGCTTCGCCGTCCGCGCCGCTGCCGGA
CAAGGCGATCGCGATCACCGTCGACGACGGCCACCGCTCGGTGTACGAACTGCTGCGCCCGATCGTGCTGCGCGAGCGGC
TGCCCGTCACGCTGTTCATCTATCCGTCCGCGATCTCGAACGCGTCGTATGCGATGACATGGGACGAACTGCGCGCGTTG
CGCGCCACCGGCCGCTTCGATATCGAATCGCACACGTGGTGGCATCCGAACTTCCGCACCGAGCGGCGGCGCCTCGCACC
CGATGCGTTCCGCCGCTTCGCCGCGACCCAGTTCGCCCATTCGCGCGCGCGGCTCGAGCGCGAAATCGGCGGGCCGGTCG
ATCTGCTCGCATGGCCGTTCGGCCTCTACGACGATGAGCTGACGTCGCTCGCCGCGCAGGCGGGCTACGTCGCGGGCTTC
ACGCTCGACGCGCGCAAGGTTCGTCGCGGCGACGCGCCGCTCGCGCTGCCGCGCTTGCTGATCGTCGACAGTTGCACGCC
GGCCGTGCTGGCGCGGATGCTCGGCGAACGCGGCGACGCGCGTGCCGATTCGCACGCCGATTTACACGTCGATTCACACG
CGGAGCAATCGCGATGA

Upstream 100 bases:

>100_bases
CGGCATGTGGACCCGAGCATGATTCGGCTGGGTTGCGTTGTTACCCGCTCACGAAAAAAGCCGTACGCTCGCGCGCCGCG
CTCTTGTGCGGCGCGCGAGC

Downstream 100 bases:

>100_bases
GCACGATCGACGGCCGTCCCCGCACACGGCGCGCGCGCGGCGTTCCACCTAAGCGCCGGCACGAAGACAAGTGCATCCCG
GTCGTGCTCGCGTGGACGCT

Product: polysaccharide deacetylase family protein

Products: NA

Alternate protein names: PNAG N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase; Biofilm polysaccharide intercellular adhesin deacetylase; Biofilm PIA deacetylase; Intercellular adhesion protein B [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTSVTSVTSVTSGTCGTCGTCGTCGTCGTCAMRVTGAAARRPATAMRCAAKRTSRRAWENTHRPRRRNRSARTRFEQPKE
RPLRHSGSRLTRFRLAAAACCLALASAARPAFAGANAPAAAEPPTDAQRPAILVYHRFSTSAPPDSMTVRVSTFGAQLAF
LRAHGYTFVPLRDVVAWAASPSAPLPDKAIAITVDDGHRSVYELLRPIVLRERLPVTLFIYPSAISNASYAMTWDELRAL
RATGRFDIESHTWWHPNFRTERRRLAPDAFRRFAATQFAHSRARLEREIGGPVDLLAWPFGLYDDELTSLAAQAGYVAGF
TLDARKVRRGDAPLALPRLLIVDSCTPAVLARMLGERGDARADSHADLHVDSHAEQSR

Sequences:

>Translated_378_residues
MTSVTSVTSVTSGTCGTCGTCGTCGTCGTCAMRVTGAAARRPATAMRCAAKRTSRRAWENTHRPRRRNRSARTRFEQPKE
RPLRHSGSRLTRFRLAAAACCLALASAARPAFAGANAPAAAEPPTDAQRPAILVYHRFSTSAPPDSMTVRVSTFGAQLAF
LRAHGYTFVPLRDVVAWAASPSAPLPDKAIAITVDDGHRSVYELLRPIVLRERLPVTLFIYPSAISNASYAMTWDELRAL
RATGRFDIESHTWWHPNFRTERRRLAPDAFRRFAATQFAHSRARLEREIGGPVDLLAWPFGLYDDELTSLAAQAGYVAGF
TLDARKVRRGDAPLALPRLLIVDSCTPAVLARMLGERGDARADSHADLHVDSHAEQSR
>Mature_377_residues
TSVTSVTSVTSGTCGTCGTCGTCGTCGTCAMRVTGAAARRPATAMRCAAKRTSRRAWENTHRPRRRNRSARTRFEQPKER
PLRHSGSRLTRFRLAAAACCLALASAARPAFAGANAPAAAEPPTDAQRPAILVYHRFSTSAPPDSMTVRVSTFGAQLAFL
RAHGYTFVPLRDVVAWAASPSAPLPDKAIAITVDDGHRSVYELLRPIVLRERLPVTLFIYPSAISNASYAMTWDELRALR
ATGRFDIESHTWWHPNFRTERRRLAPDAFRRFAATQFAHSRARLEREIGGPVDLLAWPFGLYDDELTSLAAQAGYVAGFT
LDARKVRRGDAPLALPRLLIVDSCTPAVLARMLGERGDARADSHADLHVDSHAEQSR

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introd

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Secreted, cell wall. Note=Attached to the cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family [H]

Homologues:

Organism=Escherichia coli, GI1786322, Length=240, Percent_Identity=27.9166666666667, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011330
- InterPro:   IPR002509 [H]

Pfam domain/function: PF01522 Polysacc_deac_1 [H]

EC number: NA

Molecular weight: Translated: 41365; Mature: 41234

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVTSVTSVTSGTCGTCGTCGTCGTCGTCAMRVTGAAARRPATAMRCAAKRTSRRAWEN
CCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
THRPRRRNRSARTRFEQPKERPLRHSGSRLTRFRLAAAACCLALASAARPAFAGANAPAA
CCCHHHHCCHHHHHHCCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEPPTDAQRPAILVYHRFSTSAPPDSMTVRVSTFGAQLAFLRAHGYTFVPLRDVVAWAAS
CCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCHHEEEEECCCEEEEEHHHHHHHHCC
PSAPLPDKAIAITVDDGHRSVYELLRPIVLRERLPVTLFIYPSAISNASYAMTWDELRAL
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHHHH
RATGRFDIESHTWWHPNFRTERRRLAPDAFRRFAATQFAHSRARLEREIGGPVDLLAWPF
HHCCCEECCCCCEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCC
GLYDDELTSLAAQAGYVAGFTLDARKVRRGDAPLALPRLLIVDSCTPAVLARMLGERGDA
CCCHHHHHHHHHHCCEEEEEEECHHHHHCCCCCHHHHHEEEECCCCHHHHHHHHCCCCCC
RADSHADLHVDSHAEQSR
CCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TSVTSVTSVTSGTCGTCGTCGTCGTCGTCAMRVTGAAARRPATAMRCAAKRTSRRAWEN
CCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHH
THRPRRRNRSARTRFEQPKERPLRHSGSRLTRFRLAAAACCLALASAARPAFAGANAPAA
CCCHHHHCCHHHHHHCCCHHCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEPPTDAQRPAILVYHRFSTSAPPDSMTVRVSTFGAQLAFLRAHGYTFVPLRDVVAWAAS
CCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCHHEEEEECCCEEEEEHHHHHHHHCC
PSAPLPDKAIAITVDDGHRSVYELLRPIVLRERLPVTLFIYPSAISNASYAMTWDELRAL
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEHHHHHHH
RATGRFDIESHTWWHPNFRTERRRLAPDAFRRFAATQFAHSRARLEREIGGPVDLLAWPF
HHCCCEECCCCCEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCC
GLYDDELTSLAAQAGYVAGFTLDARKVRRGDAPLALPRLLIVDSCTPAVLARMLGERGDA
CCCHHHHHHHHHHCCEEEEEEECHHHHHCCCCCHHHHHEEEECCCCHHHHHHHHCCCCCC
RADSHADLHVDSHAEQSR
CCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA