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The map label for this gene is ltaE [H]

Identifier: 76817823

GI number: 76817823

Start: 2159257

End: 2160450

Strand: Direct

Name: ltaE [H]

Synonym: BURPS1710b_A1771

Alternate gene names: 76817823

Gene position: 2159257-2160450 (Clockwise)

Preceding gene: 76818687

Following gene: 76817409

Centisome position: 67.86

GC content: 70.77

Gene sequence:

>1194_bases
ATGCGCCCGCGAACGGCTCACCGTATCGGCGCGCGAGCGCCGCGTCGCGCCCGCGCCGCTTCGGCCGCGTCAAGCGGCGC
GACGCCGAATTGCGTACACTCGAAGCCTCCGCTTCACCGCGCGAGCGCGCCGGCGCACCGCGCAATCCTCCTCTTCGACG
AGACTCCGACGGGAACCCAGATGATCGATTTACGCAGCGATACCGTGACGCGCCCGAGCGCGCCGATGCTGGCCGCGATG
ACGGCCGCCGAAGTGGGCGACGACGTGTGGGGCGACGATCCCACCGTCGCGCGCCTGCAGGCCGTGGTGGCCGAGCGCGC
GGGCAAGGAGGCGGCGCTGTTCTTTCCGAGCGGCACGCAGAGCAACCTCGCGGCGCTGATGTCGCACTGCGAGCGCGGCG
ACGAGTACATCGTCGGCCAGGCCGCGCACACGTACAAATACGAGGGCGGCGGCGCGGCGGTGCTCGGCAGCATTCAGCCG
CAGCCGATCGAGAACGCCGCGGACGGCACGCTGCCGCTCGAGAAGATCGCGGCCGCGATCAAGCCGATCGACGATCACTT
CGCCCGCTCGCGCCTGTTCACGCTTGAGAACACGATCGGCGGCAAGGTGCTGCCGGCGGGCTATGTCGACGAAGCGGTCG
CGCTCGCGCGCAGCCGCGGGCTCGCTGCGCATCTCGACGGCGCGCGCGTATGCAACGCGGCCGTCGCGTCGGGCCGCGCG
ATCGCCGAGCTGTGCGCGCCGTTCGATTCGGTGTCGATCTGCTTTTCGAAGGGGCTCGGCGCGCCGGTGGGCTCGGTGCT
CGTCGGCAGCGGCGCGCTGATCGAGCGCGCGCACCGCTGGCGCAAGGTGCTCGGCGGCGGCATGCGCCAGGCGGGCGTGC
TCGCGGCCGCGTGCCTGTATGCGCTCGAGCACAACGTCGAGCGTCTCGCCGACGATCACGCGAACGCCGAGCGCCTCGCG
CAGGGCCTCGCGCGCATCGAGCCGGTGAAGGTGCTGTCGCAGGCGACGAACATGGTGTTCGCGCAATTTCCCGAAGCCGA
TTGCGCGCCGCTCGAAGCATGGCTCAAGGAGCGCGGGATTCTCACGCAGATGCTGTATGCGTCGCGCTTCGTCACGCACT
GCGACGTGTCGCGCGACGACATCGACACGGCTGTCGCCGCGATCAGCGCGTATTTCGCGCGTTCGCGCGCTTGA

Upstream 100 bases:

>100_bases
CAGGGTACGACGCGGGCGACGGATCGCGCGCCGCGTCGATGGCGAATCCACAGCCGGATCGCGGCCGATTCGTCGCCTGA
TCGCCGGCGGGGCGCCGCCG

Downstream 100 bases:

>100_bases
CGGGAGCGGGCGCCGCCGCGGCGCGCCCGCCCGCCGCGGCGGCGCCGCGCGGCGGCGGCGCGAGCAGTTGCTGCGCGGCC
TCGACGACCCGCGACGACAG

Product: L-allo-threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MRPRTAHRIGARAPRRARAASAASSGATPNCVHSKPPLHRASAPAHRAILLFDETPTGTQMIDLRSDTVTRPSAPMLAAM
TAAEVGDDVWGDDPTVARLQAVVAERAGKEAALFFPSGTQSNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQP
QPIENAADGTLPLEKIAAAIKPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHLDGARVCNAAVASGRA
IAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVLGGGMRQAGVLAAACLYALEHNVERLADDHANAERLA
QGLARIEPVKVLSQATNMVFAQFPEADCAPLEAWLKERGILTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA

Sequences:

>Translated_397_residues
MRPRTAHRIGARAPRRARAASAASSGATPNCVHSKPPLHRASAPAHRAILLFDETPTGTQMIDLRSDTVTRPSAPMLAAM
TAAEVGDDVWGDDPTVARLQAVVAERAGKEAALFFPSGTQSNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQP
QPIENAADGTLPLEKIAAAIKPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHLDGARVCNAAVASGRA
IAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVLGGGMRQAGVLAAACLYALEHNVERLADDHANAERLA
QGLARIEPVKVLSQATNMVFAQFPEADCAPLEAWLKERGILTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA
>Mature_397_residues
MRPRTAHRIGARAPRRARAASAASSGATPNCVHSKPPLHRASAPAHRAILLFDETPTGTQMIDLRSDTVTRPSAPMLAAM
TAAEVGDDVWGDDPTVARLQAVVAERAGKEAALFFPSGTQSNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQP
QPIENAADGTLPLEKIAAAIKPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHLDGARVCNAAVASGRA
IAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVLGGGMRQAGVLAAACLYALEHNVERLADDHANAERLA
QGLARIEPVKVLSQATNMVFAQFPEADCAPLEAWLKERGILTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=334, Percent_Identity=58.9820359281437, Blast_Score=384, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI193206522, Length=346, Percent_Identity=41.907514450867, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193206524, Length=346, Percent_Identity=41.907514450867, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI193206520, Length=346, Percent_Identity=41.3294797687861, Blast_Score=229, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6320789, Length=339, Percent_Identity=37.1681415929204, Blast_Score=186, Evalue=6e-48,
Organism=Drosophila melanogaster, GI21355439, Length=365, Percent_Identity=42.1917808219178, Blast_Score=254, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 41885; Mature: 41885

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRTAHRIGARAPRRARAASAASSGATPNCVHSKPPLHRASAPAHRAILLFDETPTGTQ
CCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCE
MIDLRSDTVTRPSAPMLAAMTAAEVGDDVWGDDPTVARLQAVVAERAGKEAALFFPSGTQ
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCH
SNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQPQPIENAADGTLPLEKIAAAI
HHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHLDGARVCNAAVASGRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCHH
IAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVLGGGMRQAGVLAAACLY
HHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALEHNVERLADDHANAERLAQGLARIEPVKVLSQATNMVFAQFPEADCAPLEAWLKERGI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCH
LTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPRTAHRIGARAPRRARAASAASSGATPNCVHSKPPLHRASAPAHRAILLFDETPTGTQ
CCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCE
MIDLRSDTVTRPSAPMLAAMTAAEVGDDVWGDDPTVARLQAVVAERAGKEAALFFPSGTQ
EEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCH
SNLAALMSHCERGDEYIVGQAAHTYKYEGGGAAVLGSIQPQPIENAADGTLPLEKIAAAI
HHHHHHHHHHHCCCCEEEECCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHH
KPIDDHFARSRLFTLENTIGGKVLPAGYVDEAVALARSRGLAAHLDGARVCNAAVASGRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHCCHH
IAELCAPFDSVSICFSKGLGAPVGSVLVGSGALIERAHRWRKVLGGGMRQAGVLAAACLY
HHHHHCCCHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALEHNVERLADDHANAERLAQGLARIEPVKVLSQATNMVFAQFPEADCAPLEAWLKERGI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCH
LTQMLYASRFVTHCDVSRDDIDTAVAAISAYFARSRA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]