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The map label for this gene is cyp137 [H]

Identifier: 76817417

GI number: 76817417

Start: 1860926

End: 1862332

Strand: Direct

Name: cyp137 [H]

Synonym: BURPS1710b_A1531

Alternate gene names: 76817417

Gene position: 1860926-1862332 (Clockwise)

Preceding gene: 76817659

Following gene: 76819226

Centisome position: 58.49

GC content: 65.32

Gene sequence:

>1407_bases
ATGAATGGCCTCCCTCTGTCGCTTCCGCGAGTCGACAGCACCGATTCGCTCTTTGCGGATCCGCTCGCTTTTCTCGCACG
AGCGCGCGCACAATGCGGCGACGTCTTCGTGCTGCGGGAGCACGGTCCGATTTTTTCTCGCGCGAGCGATTGCAGCGGCG
TGATCGCCGTGTTCGGCGAACATCGGCTTCGACAAGTCTTGACCGAGACGGATACCTTCGCGCTGCCGATGTCAGCGGCG
GCGAAGATGGCGTTGCCGAAGAATCTGGTCAACCTCAACCGCGGCTTGCACAGCATGCGCGAGCCGGAGCACGGCCGGCA
CAAGCGCCTCCTGACGGGAACGGCCAACCGTGCGCTGTTCGACGCGCATCGATCCGGAATGCAAACGGATTTGAGCCGCT
TTTGCGAAATGCTGAACGGGGACGGCCGGATTTCCGTCGTGAGCCGAATGCGCGAGCTGACAGCCAAGTTGGCGTCCCGT
CTTTTTCTTGGGCCGCAGTGTGAGGAGGATGCCGAACTGACGTTTCTGCTAAGCGCGTATTTCACGTTGCGGCGCGAGGC
GTCTTCGCCCAACGCGCACGATCCGTTGCAGTACCGGGACGCGCTGATCGGCGCCGGGCGGCAACTCGATCGCGCGTTGC
GGGCGCGGATCCGGCGGTATCGAAAGGCGCCCGCCGGCGAGTGCGCGGGGCTGCTCCAGCGGCTGGCGACGGCCGGCCAG
CCGGGTTCGCCCGCGCTTTCCGAGGATGAGATCGTCGGCCACGCCAACGTGATGTTCGTGTCGAGCACGGAGCCGGTGGC
GATATCGCTGGCGTGGCTGCTGCTCGTTCTGTCGCAGTTGCCCGATCTGCGGCGTGCGCTTCGCGCGGAAAGCGCCGCCC
GCGCATCGTCGCCGGCTTCGCCGTGCGGCGCGCCATTGCTCGAGCGCGTCATCAACGAGACGCTTCGGCTCCTGACGCCC
AACGCGCTGATGGTCCGCGCCACGACGCAGGCGGCTTCGTTGCAAGGCGTCGCGCTTCCCGCGCGCTGCGAGATTGTCGT
GTGCCCGTTCCTCGTGCACCGCGAGGCCAACGCGTTTGCGCGCCCGCATGCATTCTTGCCGTCCCGATGGGAGACGGCGA
GGCCGTCGCCGTACGAGTATTTTCCATTCGGCGCCGGCGGCCATTTCTGCGCGGGGCGGAATCTCGCGCTGTCGCTGATT
GGCGAAGTGCTGTCGACGCTGTTATCGCGATTCGATTTCGTTTTGGATATCGAACAGTTTATCGACTGGCGCATTCATAT
CATGCTGATGCCGAAAGGCGACCCGACGCTCACGGCGCACCCCGTCGACGAACGCCGCGACACGCCGTCGCCGAAATGGC
GCGGGCCTGTCGCCGAGCTGTTCCATTTCGCGCCGGGGCTTTCTTGA

Upstream 100 bases:

>100_bases
GGCGGCTTCGGAAGACGTGATACTGTGACGGCAGCCATGCTGTAGCGATCAACCGGCGTAGCCACGATCGGCACGAATCG
TTCACGGACACAGCGCGCAA

Downstream 100 bases:

>100_bases
CATTTACCGGGGCGCATCCTTTAATCAGAAGCAAATCGGCATGCACACCCGACGGGATTTTTTCGGTCATCGATTCGCAT
GGCGATTTTCGGGGGTTATT

Product: putative cytochrome monooxygenase related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPCGAPLLERVINETLRLLTP
NALMVRATTQAASLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS

Sequences:

>Translated_468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPCGAPLLERVINETLRLLTP
NALMVRATTQAASLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
>Mature_468_residues
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGEHRLRQVLTETDTFALPMSAA
AKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALFDAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASR
LFLGPQCEEDAELTFLLSAYFTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPASPCGAPLLERVINETLRLLTP
NALMVRATTQAASLQGVALPARCEIVVCPFLVHREANAFARPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLI
GEVLSTLLSRFDFVLDIEQFIDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503243, Length=410, Percent_Identity=22.9268292682927, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI225903399, Length=323, Percent_Identity=24.4582043343653, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4503211, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI13435386, Length=177, Percent_Identity=27.1186440677966, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4503231, Length=222, Percent_Identity=23.8738738738739, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503213, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI16933533, Length=213, Percent_Identity=23.4741784037559, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI262290932, Length=177, Percent_Identity=24.8587570621469, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI261278370, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI261278372, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI195972896, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI195972898, Length=182, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI12383060, Length=214, Percent_Identity=23.8317757009346, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI187960086, Length=175, Percent_Identity=27.4285714285714, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI310125128, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI14550409, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI310125130, Length=341, Percent_Identity=24.3401759530792, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI190570174, Length=341, Percent_Identity=24.3401759530792, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI167466231, Length=201, Percent_Identity=24.3781094527363, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641483, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28571357, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330299, Length=178, Percent_Identity=27.5280898876405, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355669, Length=222, Percent_Identity=24.7747747747748, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR017972
- InterPro:   IPR002401 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 51446; Mature: 51446

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
HRLRQVLTETDTFALPMSAAAKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
DAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASRLFLGPQCEEDAELTFLLSAY
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
FTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPAS
CCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
PCGAPLLERVINETLRLLTPNALMVRATTQAASLQGVALPARCEIVVCPFLVHREANAFA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCCCCCCEEECCHHHHCCCCHHC
RPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLIGEVLSTLLSRFDFVLDIEQF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
CCEEEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MNGLPLSLPRVDSTDSLFADPLAFLARARAQCGDVFVLREHGPIFSRASDCSGVIAVFGE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
HRLRQVLTETDTFALPMSAAAKMALPKNLVNLNRGLHSMREPEHGRHKRLLTGTANRALF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
DAHRSGMQTDLSRFCEMLNGDGRISVVSRMRELTAKLASRLFLGPQCEEDAELTFLLSAY
HHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
FTLRREASSPNAHDPLQYRDALIGAGRQLDRALRARIRRYRKAPAGECAGLLQRLATAGQ
HHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
PGSPALSEDEIVGHANVMFVSSTEPVAISLAWLLLVLSQLPDLRRALRAESAARASSPAS
CCCCCCCCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCC
PCGAPLLERVINETLRLLTPNALMVRATTQAASLQGVALPARCEIVVCPFLVHREANAFA
CCCHHHHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCCCCCCEEECCHHHHCCCCHHC
RPHAFLPSRWETARPSPYEYFPFGAGGHFCAGRNLALSLIGEVLSTLLSRFDFVLDIEQF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDWRIHIMLMPKGDPTLTAHPVDERRDTPSPKWRGPVAELFHFAPGLS
CCEEEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]