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The map label for this gene is ackA [H]

Identifier: 76817389

GI number: 76817389

Start: 1325871

End: 1327049

Strand: Direct

Name: ackA [H]

Synonym: BURPS1710b_A1060

Alternate gene names: 76817389

Gene position: 1325871-1327049 (Clockwise)

Preceding gene: 76817791

Following gene: 76819402

Centisome position: 41.67

GC content: 72.26

Gene sequence:

>1179_bases
ATGAGCGAGCCGCTGCTGCTCACGTTCAACGCCGGCTCGTCGACGCTGAAGATCGGCCTCTACAGCGTCGCGAACGGCGA
ACCCGCGCCGCTCGGGCGCGGCAAGATCGATTTCAACCGCGCGCCGCTGCAGTTCGAATACGCGAACGGCGGCGAAGCGC
ACGCGGTGCCGCTCGCCGCGCCCGTCACCGACGATCTGCACGCGGTGCTCGACGAGGCGCTCGGCTGGATCGACGCGCAC
CTGTCGGTGCACGAGCTCGTGTCGGTCGGCCATCGCGTCGTGCACGGCGGCGACACGTTCGACGGGCCGGTGCGCATCGA
CGAGCGCACGCTCGACGCGATCGCGGCGCTCGTGCCGCTCGCGCCGCTGCATCAGCCGCAGAGCGTGCGGCTGATCCGCG
CGCTGCGCCATTTGCGGCCGCATCTGCCGCAGGTCGCATCGTTCGATACCGCGTTTCACCGCACGCAGTCCGATCTCGTG
CGGCGCTTCGCGCTGCCGCGCGCGCTGTTCGACGCAGGCATCAAGCGCTACGGTTTTCATGGGCTGTCGTACCGGTACGT
CGCCGGGCGGCTGCGCGAGCGGCATCCGTCGATTGCGCGCGGCAAGGTCGTCGCCGCGCATCTCGGCAGCGGCGCGAGCC
TGTGCGCGCTCGACGCGGGCGTGAGCCGCGACACCAGCATGGGCTTCTCGACGCTCGACGGCATTCCGATGGCCACGCGC
TGCGGCGCGCTCGACGCGGGCGTCGTGCTGCATCTGCAGAAGACGCTCGGCCGGACGCTCGACGACGTCGAGCAGATGCT
GTACCACCGCTCGGGCCTGCTCGGCGTGTCGGGCGTGAGCGGCGACGCGCGCGCGCTGCTCGCCGATCCTTCGGCCGGCG
CGCGCGACGCGCTCGAACTGTTCGCGTTCCGGATCGCGGGCGAGACCGCGCGGCTCGCGGCGACGCTCGGCGGCCTCGAC
GCGCTCGTGTTCACGGCGGGCATCGGCGAGCATCAGCCGCAGACGCGCGCGGCGGTATGCGAGCGGCTGCGCTGGCTCGG
CGTCGAGCTCGATGCGCACGCGAACGCGCGCAATGCGGAGACCGTCAGCCGCGACGGGAGCCGCGTCGCGGTGCTCGTCG
TGCCGACCGACGAGGAGCAGGTGATCGCGCGGGATGCGGCGTCGGTGCTGCATGCCTGA

Upstream 100 bases:

>100_bases
TCATCCTGACGAGCCGCGCGGACAGCCTGCGCGTGCGCATCGCATCCGCCGCGCTCGCGAAGCTCGTTGCCGAAAGGACG
CGCGCCGGCGCGCTCGCGTC

Downstream 100 bases:

>100_bases
GCGAGGGGAACGCCGGACGACGGCGGCCATGGGAGCGCAGAGCGGCGTCGGCCGAACTTCGGGCCCCGCGCACGCGAGAC
GAGTGCGATTGCGCGCCTGA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAH
LSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLV
RRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATR
CGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLD
ALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA

Sequences:

>Translated_392_residues
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAH
LSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLV
RRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATR
CGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLD
ALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>Mature_391_residues
SEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHL
SVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLVR
RFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRC
GALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDA
LVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=400, Percent_Identity=37.5, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1788633, Length=400, Percent_Identity=35, Blast_Score=208, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41753; Mature: 41622

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAA
CCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEC
PVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECHHHHHHHHHHHHH
APLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFH
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATR
CCHHHHHHHHHHHCCCCCHHCCEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCCCHHH
CGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALEL
CCCCCCHHHEEEHHHHCCCHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCHHHHHHH
FAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAE
HHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCH
TVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
HHCCCCCEEEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAA
CCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEC
PVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEECHHHHHHHHHHHHH
APLHQPQSVRLIRALRHLRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFH
CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATR
CCHHHHHHHHHHHCCCCCHHCCEEEEECCCCCCEEEECCCCCCCCCCCCHHHCCCCCHHH
CGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALEL
CCCCCCHHHEEEHHHHCCCHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCCHHHHHHH
FAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAE
HHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEECCCCCCCCH
TVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
HHCCCCCEEEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]