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The map label for this gene is aspC [H]

Identifier: 75909900

GI number: 75909900

Start: 4604878

End: 4606053

Strand: Direct

Name: aspC [H]

Synonym: Ava_3695

Alternate gene names: 75909900

Gene position: 4604878-4606053 (Clockwise)

Preceding gene: 75909899

Following gene: 75909901

Centisome position: 72.34

GC content: 41.92

Gene sequence:

>1176_bases
ATGACTAACTTCACTTCTCGGATGCAGGCGGTACAGTCGCCGATTATTCCTGTGGTTGGGGAATTAATTCAAAATTCGCC
AGGGACTATTTCTTTGGGACAGGGTGTGGTTTCTTATAGTCCGCCACCAGAAGCTATTGAGCTTTTGCCGAAATTTTTGG
CTGACCCTGCTAATAATTTATATAAAGCTGTGGAGGGTATTCCTCCTTTGTTGAATGCGTTGACAGACAAATTGTCTACG
TTCAACAAGATGGAAATCACGACAGATAACTGTATTGTGGTGACGGCGGGAAGCAATATGGCGTTTATGAACGCTATTTT
GGCGATTACTTCTCCTGGTGATGAAATTATTCTCAATACGCCTTACTACTTCAACCACGAAATGGCGATCGCAATGGCTG
GTTGTCGTGCAGTGTTGGTGGAAACCGATGAAAATTACCAACTGCGTCCAGAGGCGATCGCTCAAGCTATTACCCCAAAA
ACCCGCGCGGTGGTCACAATCTCCCCCAATAATCCGACAGGTGTTGTCTATTGTGAAGATTTATTACGTAATGTAAACCA
AATTTGCGCTAATTGTGGCATCTATCACATTAGTGATGAGGCTTATGAATACTTTACTTACGATGGTGTAAAGCACGTTT
CTCCAGCCTCATTTGCTGGGAGTAGTGAGTATACAATTTCCCTTTATAGTCTTTCTAAAGCTTACGGGTTTGCCAGTTGG
CGAATTGGCTATATGGTGATTCCCAAACATCTGCTTGTCGCCATTAAAAAAGTCCAAGATACGATTTTGATTTGTCCGCC
TGTGGTTTCTCAGTATGCAGCTTTGGGAGCATTGCAAGCAAAACCAGAATATTTACAAGATCATATTCAGGCGATCGCTC
AAGTGAGGAAAATAGTATTCGACTACCTCAACCAACTCCAAGGCTTATGTACTATTACTCCCGCCGATGGTGCTTTCTAT
GTTTTCCTGAAAGTGCACACTCAAATAGATGCTTTTACACTAGTCAAACAACTAATTCAAGAATATAAAGTGGCTGTAAT
TCCCGGTACAACTTTTGGCATGGAAAGTGGTTGTTATCTGCGGGTTGCTTACGGTGCGTTGCAAAAAGATACAGTCCAAG
AAGGTATTGAAAGGTTAGTACAAGGATTGAAAACAATTTTATATCCAGAAAAATGA

Upstream 100 bases:

>100_bases
CGGCTTTTACGATGCAGGGGGAGTGGAGGTGATAACTTGGGAACGGGGAAACAGTGTGGAGGCTGTTGACTGTTGACCGT
TGACTACTGACTAATGACTA

Downstream 100 bases:

>100_bases
GATAATAATTTTTAGAATCCATCAATCAGCAGTCAGAATCAATAAGACTTTGATATTACAGCTTATACCGTTTCTTGATG
TAGCTTGCCTAGCGTAGCCA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPKFLADPANNLYKAVEGIPPLLNALTDKLST
FNKMEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAIAMAGCRAVLVETDENYQLRPEAIAQAITPK
TRAVVTISPNNPTGVVYCEDLLRNVNQICANCGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIQAIAQVRKIVFDYLNQLQGLCTITPADGAFY
VFLKVHTQIDAFTLVKQLIQEYKVAVIPGTTFGMESGCYLRVAYGALQKDTVQEGIERLVQGLKTILYPEK

Sequences:

>Translated_391_residues
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPKFLADPANNLYKAVEGIPPLLNALTDKLST
FNKMEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAIAMAGCRAVLVETDENYQLRPEAIAQAITPK
TRAVVTISPNNPTGVVYCEDLLRNVNQICANCGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIQAIAQVRKIVFDYLNQLQGLCTITPADGAFY
VFLKVHTQIDAFTLVKQLIQEYKVAVIPGTTFGMESGCYLRVAYGALQKDTVQEGIERLVQGLKTILYPEK
>Mature_390_residues
TNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPKFLADPANNLYKAVEGIPPLLNALTDKLSTF
NKMEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAIAMAGCRAVLVETDENYQLRPEAIAQAITPKT
RAVVTISPNNPTGVVYCEDLLRNVNQICANCGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASWR
IGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIQAIAQVRKIVFDYLNQLQGLCTITPADGAFYV
FLKVHTQIDAFTLVKQLIQEYKVAVIPGTTFGMESGCYLRVAYGALQKDTVQEGIERLVQGLKTILYPEK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=389, Percent_Identity=26.9922879177378, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=27.1317829457364, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI95147551, Length=251, Percent_Identity=31.0756972111554, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169881279, Length=251, Percent_Identity=31.0756972111554, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169881281, Length=164, Percent_Identity=31.0975609756098, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1786816, Length=359, Percent_Identity=27.2980501392758, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=26.4305177111717, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788627, Length=371, Percent_Identity=26.4150943396226, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787909, Length=240, Percent_Identity=25.8333333333333, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=426, Percent_Identity=24.6478873239437, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=25.1282051282051, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=390, Percent_Identity=25.1282051282051, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=351, Percent_Identity=22.7920227920228, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=28.6082474226804, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=357, Percent_Identity=25.2100840336134, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=398, Percent_Identity=23.3668341708543, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573069, Length=313, Percent_Identity=24.9201277955272, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646114, Length=313, Percent_Identity=24.9201277955272, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573067, Length=313, Percent_Identity=24.9201277955272, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28573065, Length=313, Percent_Identity=24.9201277955272, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI18859735, Length=310, Percent_Identity=23.8709677419355, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42898; Mature: 42767

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPKFLADPANNL
CCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
YKAVEGIPPLLNALTDKLSTFNKMEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNT
HHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHEEEEEECCCCEEEECC
PYYFNHEMAIAMAGCRAVLVETDENYQLRPEAIAQAITPKTRAVVTISPNNPTGVVYCED
CEEECCHHEEEEECCEEEEEECCCCCEECHHHHHHHCCCCCEEEEEECCCCCCEEEEHHH
LLRNVNQICANCGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
HHHHHHHHHHHCCEEEECCCHHHEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHCCHHE
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIQAIAQVRKIVF
EEEEEEHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DYLNQLQGLCTITPADGAFYVFLKVHTQIDAFTLVKQLIQEYKVAVIPGTTFGMESGCYL
HHHHHHCCCEEEECCCCEEEEEEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEE
RVAYGALQKDTVQEGIERLVQGLKTILYPEK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPKFLADPANNL
CCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
YKAVEGIPPLLNALTDKLSTFNKMEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNT
HHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHEEEEEECCCCEEEECC
PYYFNHEMAIAMAGCRAVLVETDENYQLRPEAIAQAITPKTRAVVTISPNNPTGVVYCED
CEEECCHHEEEEECCEEEEEECCCCCEECHHHHHHHCCCCCEEEEEECCCCCCEEEEHHH
LLRNVNQICANCGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
HHHHHHHHHHHCCEEEECCCHHHEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHCCHHE
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIQAIAQVRKIVF
EEEEEEHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DYLNQLQGLCTITPADGAFYVFLKVHTQIDAFTLVKQLIQEYKVAVIPGTTFGMESGCYL
HHHHHHCCCEEEECCCCEEEEEEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEE
RVAYGALQKDTVQEGIERLVQGLKTILYPEK
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]