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The map label for this gene is asd [H]

Identifier: 75909811

GI number: 75909811

Start: 4498293

End: 4499336

Strand: Direct

Name: asd [H]

Synonym: Ava_3606

Alternate gene names: 75909811

Gene position: 4498293-4499336 (Clockwise)

Preceding gene: 75909805

Following gene: 75909812

Centisome position: 70.66

GC content: 46.46

Gene sequence:

>1044_bases
TTGTCTAAAACGTATCGTGTAGCTATTTTGGGAGCAACTGGTGCTGTCGGCACAGAGTTGCTGGAGTTGTTGGAAAGCCG
TAATTTTCCGGTGGCGGAACTAAAATTATTGGCATCAGAAAGGAGCGTAGGCCGATCGCTCCCTTTTAAAGGTGAAAATA
TAATAGTCGAGGCAGTGAGCGATCGCGCCTTGGAAAATGTTGATATAGTTTTAGCCAGCGCTGGTGGTTCCACATCCAAA
GCTTGGGCATCTGTAGCAGTGGAAAAAGGTGCCGTAGTTATCGATAACTCCAGTGCCTTCCGCATGAACCCAGATGTTCC
CCTGATTGTGCCAGAGGTGAACCCCCAAGCCGCCGCCGACCACAAAGGCATCATTGCCAACCCCAACTGCACAACTATTT
TGATGACCTTGGCTGTATGGCCACTACATCAAGTTAGACCAGTACAACGCATTGTGGCAGCAACTTACCAGTCTGCCAGT
GGTGCAGGTGCTAAAGCAATGGCAGAAGTGAAAACCCAAAGCAGTGCCATCTTGAAAGGTGAGGAACCAGTCGCCGAAGT
ATTACCTTACCCCCTAGCATTTAATTTATTTCCCCATAACTCTCCCTTGACAGATTCGGGGTATTGTGAGGAAGAGTTGA
AAATGGTCAACGAAACCCGCAAAATCTTTGGTACACAAGAAATTAGAATTACAGCTACTTGTGTACGGGTTCCCGTACTA
CGCGCCCACTCAGAAGCAATTAATCTAGAGTTCGCAGAACCATTTTCTCCAGACGAAGCGAGAGAAATTTTAAGTCACGC
ACCTGGAGTAAAATTATTGGAAGACTGGGGAAAAAATTACTTCCCCATGCCCATTGAAGCTAGTGGTCGTGATGAAGTTT
TAGTGGGGAGAATCCGCCAAGATATTTCTCACCCTTGTGGTTTAGAACTCTGGCTTTGTGGCGACCAAATTCGTAAAGGC
GCAGCATTGAACGCGGTACAAATAGCCGAGTTGTTGGTAGAAAAGAATTTACTCCAACCTACAAAAGCTTATGTTGCTAG
GTAG

Upstream 100 bases:

>100_bases
AATATTTGATTATTCTTATTTTCAAAGACTGGATAAATTATAAATCTGTAAGAAACCACCAAAAACTTAACCGTAACCTC
TGAGGAAGGAGGATTTTAGT

Downstream 100 bases:

>100_bases
TCAGTGGTCATTGGTCAGTGGTCAGTAGCCATCATGAACTGCATCAGGGATGGGGGATTAGGGGCTAGGAACTCAGCACA
GGCTACACGCCCCAAAACCG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFKGENIIVEAVSDRALENVDIVLASAGGSTSK
AWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSAS
GAGAKAMAEVKTQSSAILKGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
RAHSEAINLEFAEPFSPDEAREILSHAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKG
AALNAVQIAELLVEKNLLQPTKAYVAR

Sequences:

>Translated_347_residues
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFKGENIIVEAVSDRALENVDIVLASAGGSTSK
AWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSAS
GAGAKAMAEVKTQSSAILKGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
RAHSEAINLEFAEPFSPDEAREILSHAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKG
AALNAVQIAELLVEKNLLQPTKAYVAR
>Mature_346_residues
SKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFKGENIIVEAVSDRALENVDIVLASAGGSTSKA
WASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAADHKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASG
AGAKAMAEVKTQSSAILKGEEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVLR
AHSEAINLEFAEPFSPDEAREILSHAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQDISHPCGLELWLCGDQIRKGA
ALNAVQIAELLVEKNLLQPTKAYVAR

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=343, Percent_Identity=37.3177842565598, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=31.0924369747899, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=27.6923076923077, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37536; Mature: 37404

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFKGENIIVEAVS
CCCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHH
DRALENVDIVLASAGGSTSKAWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAAD
CCCCCCEEEEEEECCCCCHHHHHHHEEECCEEEEECCCCEEECCCCCEEEECCCCCCCCC
HKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASGAGAKAMAEVKTQSSAILKG
CCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECC
EEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
CCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHH
RAHSEAINLEFAEPFSPDEAREILSHAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQ
HCCCHHEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DISHPCGLELWLCGDQIRKGAALNAVQIAELLVEKNLLQPTKAYVAR
HHCCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
SKTYRVAILGATGAVGTELLELLESRNFPVAELKLLASERSVGRSLPFKGENIIVEAVS
CCEEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEHH
DRALENVDIVLASAGGSTSKAWASVAVEKGAVVIDNSSAFRMNPDVPLIVPEVNPQAAAD
CCCCCCEEEEEEECCCCCHHHHHHHEEECCEEEEECCCCEEECCCCCEEEECCCCCCCCC
HKGIIANPNCTTILMTLAVWPLHQVRPVQRIVAATYQSASGAGAKAMAEVKTQSSAILKG
CCCEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECC
EEPVAEVLPYPLAFNLFPHNSPLTDSGYCEEELKMVNETRKIFGTQEIRITATCVRVPVL
CCCHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEHHHHH
RAHSEAINLEFAEPFSPDEAREILSHAPGVKLLEDWGKNYFPMPIEASGRDEVLVGRIRQ
HCCCHHEEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
DISHPCGLELWLCGDQIRKGAALNAVQIAELLVEKNLLQPTKAYVAR
HHCCCCCCEEEEECHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]