Click here to switch to the map view.

The map label for this gene is argS

Identifier: 75909766

GI number: 75909766

Start: 4433368

End: 4435134

Strand: Direct

Name: argS

Synonym: Ava_3561

Alternate gene names: 75909766

Gene position: 4433368-4435134 (Clockwise)

Preceding gene: 75909764

Following gene: 75909767

Centisome position: 69.64

GC content: 41.71

Gene sequence:

>1767_bases
ATGAACGCTACACAAGAACAACTAAAGGTAAAACTTGAGCAGGCTTTGATTGCTGCTTTTGGTGATGAGTACGCCGGAGT
AGACCCGATTTTGGTTACTGCTAGCAATCCTAAGTTTGGTGATTATCAAGCCAACGTTGCTTTGTCGCTGAGTAAAAAGT
TAGGACAGCCACCGCGAGCGATCGCCTCTGCTATTGTAGAAAAACTAGATGTATCAGAAATCTGCGAAACTCCAGAAATC
GCTGGCCCTGGTTTTATTAACCTGAAGTTGAAAACCGCTTACCTAGAAGCGCAACTAAACGCTATTCAAGCAGATTCTAG
ACTAGGCGTTCCTACAGCCAAACACCCACAACGGGAAATCGTCGATTTTTCTAGTCCGAATATTGCCAAAGAGATGCACG
TCGGACACCTACGTTCTACCATCATCGGTGATTCCATCGCCCGGATTCTCGAATTTCGCGGTCATGATGTATTGCGGTTA
AATCATGTAGGTGATTGGGGAACGCAATTTGGGATGTTAATCACTTACCTACGGGAAGTTTCCCCAGAAGCCTTAACTAC
TGCAAATGCTTTAGATATCGGTGATTTAGTAAGTTTTTATCGCCAAGCCAAGCAACGGTTTGATGCTGATGAAGCCTTCC
AAGAAACAGCACGCCAAGAAGTTGTGAGATTACAAGCAGGTGCAACAGATACCCTCCATGCTTGGAAGTTGTTGTGTGAA
CAATCACGCCAAGAGTTTCAGGTAATTTATGATTTACTTGATGTCAAATTAACTGAACGAGGCGAATCTTTTTATAACCC
CTTACTCCCAACAGTTGTAGAAGGTTTAGAAGCATCCGGTTTATTGGTAGAAAACCAAGGTGCGAAATGTGTTTTCTTGG
ATGGCTTTACTAATAGAGAAGGTGAACCTCTACCCTTGATTGTGCAGAAATCTGATGGTGGTTATAACTACGCCACAACA
GATTTAGCTGCGTTACGTTACCGGATTCAAAAAGATGAAGCCAAACGCATAGTTTATGTAACAGATGCAGGACAAGCCAA
CCACTTTGCCCAATTCTTCCAAGTAGCACGTAAAGCTGGATGGATTCCTAATGATGTGGAATTGGTTCATGTTCCCTTTG
GTTTGGTGTTGGGTGAAGATGGTAAAAAATTCAAAACTCGTTCTGGCGATACTGTGCGGTTACGAGATTTATTAGATGAA
GCAGTTTCTCGCGCCCATGCAGATTTAGAAGAGAGATTAAAAGCAGAAGAACGGGAAGAAACTCCAGAATTCATTGATAA
AGTTGCGGAAGTAGTTGGTATTAGTGCAGTTAAGTACGCCGATTTAAGTCAAAATCGCACAAGTAACTACATTTTCAGCT
ATGACAAAATGCTGGATTTGAAAGGCAATACAGCACCATATATGTTGTATGCTTATGCCCGGATTCAAGGGATTAGCCGT
AAGGGTGGAATTAACTTTGCAGATTTGGGAGATAATGCCAAAGTCATCTTGCAGCATGACACAGAATTTGCACTGGCTAA
ATATCTACTGCAATTAGGCGAAGTGATTAGTACTGTAGAAGCAGACTTATTACCTAATCGTTTATGTGAATATCTTTACG
AATTAAGTAAGAAGTTTAATACGTTTTATGACCGTAATCAAGGGGTACAGGTTTTGAGTGCAGAAGAACCTCTGCGGACA
TCACGTTTAGTTCTGTGTGATTTGACAGCGAGAACTTTAAAACTCGGCTTATCTTTGTTGGGGATTCAGGTGTTAGAGAG
AATGTAA

Upstream 100 bases:

>100_bases
TGAGATTAGCTGACTATATTTTAAGGTTAAAATAATCAAGCCTTTGAGAATATCCAACACTCAACAGCCGCATTCCGCCT
GTGACAGATAACATTTATAT

Downstream 100 bases:

>100_bases
CTATCAACCTACCATTCTTAACAATATCTTTAAGGGAGGTAAATTCATGGTAATGAAACTGATCACAGCAAAAATTGAAA
ATTTTAAAAGCTTAGGCAAT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNATQEQLKVKLEQALIAAFGDEYAGVDPILVTASNPKFGDYQANVALSLSKKLGQPPRAIASAIVEKLDVSEICETPEI
AGPGFINLKLKTAYLEAQLNAIQADSRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGATDTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVEGLEASGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIVYVTDAGQANHFAQFFQVARKAGWIPNDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AVSRAHADLEERLKAEEREETPEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGGINFADLGDNAKVILQHDTEFALAKYLLQLGEVISTVEADLLPNRLCEYLYELSKKFNTFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM

Sequences:

>Translated_588_residues
MNATQEQLKVKLEQALIAAFGDEYAGVDPILVTASNPKFGDYQANVALSLSKKLGQPPRAIASAIVEKLDVSEICETPEI
AGPGFINLKLKTAYLEAQLNAIQADSRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGATDTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVEGLEASGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIVYVTDAGQANHFAQFFQVARKAGWIPNDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AVSRAHADLEERLKAEEREETPEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGGINFADLGDNAKVILQHDTEFALAKYLLQLGEVISTVEADLLPNRLCEYLYELSKKFNTFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM
>Mature_588_residues
MNATQEQLKVKLEQALIAAFGDEYAGVDPILVTASNPKFGDYQANVALSLSKKLGQPPRAIASAIVEKLDVSEICETPEI
AGPGFINLKLKTAYLEAQLNAIQADSRLGVPTAKHPQREIVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRL
NHVGDWGTQFGMLITYLREVSPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGATDTLHAWKLLCE
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVEGLEASGLLVENQGAKCVFLDGFTNREGEPLPLIVQKSDGGYNYATT
DLAALRYRIQKDEAKRIVYVTDAGQANHFAQFFQVARKAGWIPNDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDE
AVSRAHADLEERLKAEEREETPEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
KGGINFADLGDNAKVILQHDTEFALAKYLLQLGEVISTVEADLLPNRLCEYLYELSKKFNTFYDRNQGVQVLSAEEPLRT
SRLVLCDLTARTLKLGLSLLGIQVLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=575, Percent_Identity=45.7391304347826, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI197100773, Length=539, Percent_Identity=32.8385899814471, Blast_Score=227, Evalue=2e-59,
Organism=Escherichia coli, GI1788184, Length=589, Percent_Identity=48.7266553480475, Blast_Score=532, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI71985061, Length=595, Percent_Identity=41.5126050420168, Blast_Score=437, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI71985068, Length=577, Percent_Identity=41.7677642980936, Blast_Score=419, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17532153, Length=488, Percent_Identity=25.6147540983607, Blast_Score=129, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320548, Length=547, Percent_Identity=31.4442413162706, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321883, Length=595, Percent_Identity=26.3865546218487, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI18859963, Length=605, Percent_Identity=42.6446280991736, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI28571570, Length=486, Percent_Identity=30.2469135802469, Blast_Score=166, Evalue=5e-41,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ANAVT (Q3M769)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_324062.1
- ProteinModelPortal:   Q3M769
- STRING:   Q3M769
- GeneID:   3679585
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3561
- NMPDR:   fig|240292.3.peg.4445
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   Q3M769
- ProtClustDB:   PRK01611
- BioCyc:   AVAR240292:AVA_3561-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 65554; Mature: 65554

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATQEQLKVKLEQALIAAFGDEYAGVDPILVTASNPKFGDYQANVALSLSKKLGQPPRA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEECCEEEEEHHHCCCCHHH
IASAIVEKLDVSEICETPEIAGPGFINLKLKTAYLEAQLNAIQADSRLGVPTAKHPQREI
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRLNHVGDWGTQFGMLITYLREV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
SPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGATDTLHAWKLLCE
CCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVEGLEASGLLVENQGAKCVFLDGFTNRE
HHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCC
GEPLPLIVQKSDGGYNYATTDLAALRYRIQKDEAKRIVYVTDAGQANHFAQFFQVARKAG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCC
WIPNDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAVSRAHADLEERLKAEEREE
CCCCCCEEEEECEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHCC
TPEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
CHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEECCEEECCCCCCCEEEEEHHHHHCCCC
KGGINFADLGDNAKVILQHDTEFALAKYLLQLGEVISTVEADLLPNRLCEYLYELSKKFN
CCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYDRNQGVQVLSAEEPLRTSRLVLCDLTARTLKLGLSLLGIQVLERM
HHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNATQEQLKVKLEQALIAAFGDEYAGVDPILVTASNPKFGDYQANVALSLSKKLGQPPRA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEECCEEEEEHHHCCCCHHH
IASAIVEKLDVSEICETPEIAGPGFINLKLKTAYLEAQLNAIQADSRLGVPTAKHPQREI
HHHHHHHHCCHHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHH
VDFSSPNIAKEMHVGHLRSTIIGDSIARILEFRGHDVLRLNHVGDWGTQFGMLITYLREV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHC
SPEALTTANALDIGDLVSFYRQAKQRFDADEAFQETARQEVVRLQAGATDTLHAWKLLCE
CCHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QSRQEFQVIYDLLDVKLTERGESFYNPLLPTVVEGLEASGLLVENQGAKCVFLDGFTNRE
HHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCC
GEPLPLIVQKSDGGYNYATTDLAALRYRIQKDEAKRIVYVTDAGQANHFAQFFQVARKAG
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCC
WIPNDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAVSRAHADLEERLKAEEREE
CCCCCCEEEEECEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHCC
TPEFIDKVAEVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYAYARIQGISR
CHHHHHHHHHHHCCHHHEECCCCCCCCCCEEEEECCEEECCCCCCCEEEEEHHHHHCCCC
KGGINFADLGDNAKVILQHDTEFALAKYLLQLGEVISTVEADLLPNRLCEYLYELSKKFN
CCCCCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYDRNQGVQVLSAEEPLRTSRLVLCDLTARTLKLGLSLLGIQVLERM
HHHCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA