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The map label for this gene is glmS [H]

Identifier: 75909691

GI number: 75909691

Start: 4322126

End: 4324027

Strand: Direct

Name: glmS [H]

Synonym: Ava_3485

Alternate gene names: 75909691

Gene position: 4322126-4324027 (Clockwise)

Preceding gene: 75909690

Following gene: 75909692

Centisome position: 67.9

GC content: 45.32

Gene sequence:

>1902_bases
ATGTGTGGCATCGTTGGGTATATCGGAACTCAAGCAGCAACCGAGATTTTGTTGGCTGGGCTAGAAAAACTAGAGTATCG
CGGTTACGATTCCGCAGGTATAGCTACGGTTTGGGAAGGAGATGTGAATTGTGTCAGGGCAAAGGGAAAACTCCATAACC
TGCGTTCTAAACTAGAACAGTTGGCTACTCCATCTCAAATTGGTATTGGTCATACACGCTGGGCAACTCATGGTAAACCA
GAGGAGTATAATGCCCATCCCCATTTAGATACAGCCATGCGAATCGCTGTTGTGCAGAATGGGATTATTGAAAATTACCG
CGAGTTACGCGACGAACTGAAACAGAAAGGACATGAGTTTCGTTCGGAAACTGATACAGAAGTTATTCCTCACCTTATAG
CCGAATTTTTAAAAAACCTCCCTTCCCCAGCGCTTCCTACCTCCTCCTCTTCCTTATTGGAAGCGATACGCCAAGCTGTT
AACCACCTGCAAGGGGCATTTGCGATCGCTGTTATCTCTGCTGACTATCCTGACGAATTGATTGTTGTCCGCCAGCAAGC
GCCCCTGGTGATAGGATTCGGGCAAGGGGAGTTCTTTTGCGCCTCCGACACGCCGGCGATCGTTTCCCATACTCGCGCAG
TCTTACCCCTGGAGAATGGCGAAATTGCCCGTCTGACACCCCTGGGAGTGGAGATTTATAACTTTGCTGGGGACAGACTG
AAAAAACAACCCCGCCTGCTCAACTTGAATCCCACAATGGTAGAGAAGCAGGGATTCAAACACTTCATGCTCAAGGAAAT
TTATGAGCAACCAGGAGTAGTCAGAGCGAGTTTAGAAGCATACTTTAATCCCGATACTAATACTGATGAATCCTTTACAT
CACCAGTTAATTTGGGTTTATCTGAAGAAATCTATGCAGATTTAGAACAAATTCATATTGTTGCCTGTGGTACGAGTTGG
CACGCCGCCTTAGTAGGAAAGTATTTACTTGAACAATTAGCAGGAATTTCCACTCAAGTACATTATGCTTCTGAGTATCG
CTATGCCCCATCACCATTAACAGCGAATACATTGATTATCGGTGTTACTCAGTCAGGGGAAACGGCTGATACCCTAGCCG
CCTTAGCGATGGAAAAAGAACGCCGCCAAGGCAAAGAAGCCAAATATCAGGCGCGACTCTTGGGTATTACCAATCGTCCA
GAAAGTAGCCTTGGTCATCTTGTACCCCATATTATTAATACCCTGGCAGGGATTGAAATTGGTGTAGCAGCGACTAAAAC
CTTTGTTGCTCAACTTATGGCGTTTTATGCCCTAGCCTTGGATTTAGCCTATCATCGCCAAACAGTAGCACCAGATAAAC
TCGCAGATATTATTCAAGGTTTACGTCAGATACCTAAGGAAATCGAAGCTACCTTAGAACGTCAGGAAAAATTAACAGAA
CATCTAGCCCATGAATTTGCAGAAACCCAAGACTTCATCTTTTTGGGCAGAGGAATTAACTTCCCTATTGCTTTAGAAGG
AGCATTGAAATTAAAAGAAATCAGCTACATTCACGCAGAAGGTTATCCGGCTGGGGAAATGAAACACGGCCCCATTGCAT
TATTAGATGCCAAAGTGCCGGTAGTGGCGATCGCCTATCCTGGTAGTGTGTATGAAAAAGTGATTTCCAATTCTCAAGAA
GCCAAAGCCAGAGATTCCCGGTTAATTGGTGTAACACCAGTCAATGATGGCGAAGCGGCGGAAATCTTTAACGATTTGCT
TCCTGTATCATCAGTAGATGAATTACTATCGCCCATCCTCACAGTAGTGCCATTGCAACTATTGGCTTACCACATCGCCG
CCCGTCGCGGTTTGGATGTCGATCAGCCTCGGAATTTAGCAAAATCAGTGACTGTGGAATAA

Upstream 100 bases:

>100_bases
ATTGTTGACTCTTGACTGCTGACAACCGACCACTGACAACTAACAACTGACAAATGACTATACTGGATTTAATTATCCTG
AAAAAAGGGTGGTGTGAGCA

Downstream 100 bases:

>100_bases
ATAAATGTGGAGGAATAATTCGGTTCAACAATATATAATTCGGTTCAACAATTAATAAAACGATTGAACAATAACCTCTA
AAGGAGTACGATTGTACCAA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 633; Mature: 633

Protein sequence:

>633_residues
MCGIVGYIGTQAATEILLAGLEKLEYRGYDSAGIATVWEGDVNCVRAKGKLHNLRSKLEQLATPSQIGIGHTRWATHGKP
EEYNAHPHLDTAMRIAVVQNGIIENYRELRDELKQKGHEFRSETDTEVIPHLIAEFLKNLPSPALPTSSSSLLEAIRQAV
NHLQGAFAIAVISADYPDELIVVRQQAPLVIGFGQGEFFCASDTPAIVSHTRAVLPLENGEIARLTPLGVEIYNFAGDRL
KKQPRLLNLNPTMVEKQGFKHFMLKEIYEQPGVVRASLEAYFNPDTNTDESFTSPVNLGLSEEIYADLEQIHIVACGTSW
HAALVGKYLLEQLAGISTQVHYASEYRYAPSPLTANTLIIGVTQSGETADTLAALAMEKERRQGKEAKYQARLLGITNRP
ESSLGHLVPHIINTLAGIEIGVAATKTFVAQLMAFYALALDLAYHRQTVAPDKLADIIQGLRQIPKEIEATLERQEKLTE
HLAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVAIAYPGSVYEKVISNSQE
AKARDSRLIGVTPVNDGEAAEIFNDLLPVSSVDELLSPILTVVPLQLLAYHIAARRGLDVDQPRNLAKSVTVE

Sequences:

>Translated_633_residues
MCGIVGYIGTQAATEILLAGLEKLEYRGYDSAGIATVWEGDVNCVRAKGKLHNLRSKLEQLATPSQIGIGHTRWATHGKP
EEYNAHPHLDTAMRIAVVQNGIIENYRELRDELKQKGHEFRSETDTEVIPHLIAEFLKNLPSPALPTSSSSLLEAIRQAV
NHLQGAFAIAVISADYPDELIVVRQQAPLVIGFGQGEFFCASDTPAIVSHTRAVLPLENGEIARLTPLGVEIYNFAGDRL
KKQPRLLNLNPTMVEKQGFKHFMLKEIYEQPGVVRASLEAYFNPDTNTDESFTSPVNLGLSEEIYADLEQIHIVACGTSW
HAALVGKYLLEQLAGISTQVHYASEYRYAPSPLTANTLIIGVTQSGETADTLAALAMEKERRQGKEAKYQARLLGITNRP
ESSLGHLVPHIINTLAGIEIGVAATKTFVAQLMAFYALALDLAYHRQTVAPDKLADIIQGLRQIPKEIEATLERQEKLTE
HLAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVAIAYPGSVYEKVISNSQE
AKARDSRLIGVTPVNDGEAAEIFNDLLPVSSVDELLSPILTVVPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
>Mature_633_residues
MCGIVGYIGTQAATEILLAGLEKLEYRGYDSAGIATVWEGDVNCVRAKGKLHNLRSKLEQLATPSQIGIGHTRWATHGKP
EEYNAHPHLDTAMRIAVVQNGIIENYRELRDELKQKGHEFRSETDTEVIPHLIAEFLKNLPSPALPTSSSSLLEAIRQAV
NHLQGAFAIAVISADYPDELIVVRQQAPLVIGFGQGEFFCASDTPAIVSHTRAVLPLENGEIARLTPLGVEIYNFAGDRL
KKQPRLLNLNPTMVEKQGFKHFMLKEIYEQPGVVRASLEAYFNPDTNTDESFTSPVNLGLSEEIYADLEQIHIVACGTSW
HAALVGKYLLEQLAGISTQVHYASEYRYAPSPLTANTLIIGVTQSGETADTLAALAMEKERRQGKEAKYQARLLGITNRP
ESSLGHLVPHIINTLAGIEIGVAATKTFVAQLMAFYALALDLAYHRQTVAPDKLADIIQGLRQIPKEIEATLERQEKLTE
HLAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVPVVAIAYPGSVYEKVISNSQE
AKARDSRLIGVTPVNDGEAAEIFNDLLPVSSVDELLSPILTVVPLQLLAYHIAARRGLDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=704, Percent_Identity=34.375, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI205277386, Length=703, Percent_Identity=33.4281650071124, Blast_Score=360, Evalue=2e-99,
Organism=Escherichia coli, GI1790167, Length=634, Percent_Identity=45.1104100946372, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1788651, Length=177, Percent_Identity=28.2485875706215, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17532899, Length=736, Percent_Identity=32.2010869565217, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17532897, Length=446, Percent_Identity=35.6502242152466, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17539970, Length=446, Percent_Identity=35.8744394618834, Blast_Score=242, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6322745, Length=447, Percent_Identity=35.3467561521253, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6323731, Length=455, Percent_Identity=27.9120879120879, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323730, Length=210, Percent_Identity=35.2380952380952, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357745, Length=707, Percent_Identity=34.6534653465347, Blast_Score=377, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 69395; Mature: 69395

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYIGTQAATEILLAGLEKLEYRGYDSAGIATVWEGDVNCVRAKGKLHNLRSKLEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHH
LATPSQIGIGHTRWATHGKPEEYNAHPHLDTAMRIAVVQNGIIENYRELRDELKQKGHEF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSETDTEVIPHLIAEFLKNLPSPALPTSSSSLLEAIRQAVNHLQGAFAIAVISADYPDEL
HCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCE
IVVRQQAPLVIGFGQGEFFCASDTPAIVSHTRAVLPLENGEIARLTPLGVEIYNFAGDRL
EEEEECCCEEEEECCCCEEECCCCCHHHHCCEEEEEECCCCEEEEEECCEEHHHCCCHHH
KKQPRLLNLNPTMVEKQGFKHFMLKEIYEQPGVVRASLEAYFNPDTNTDESFTSPVNLGL
HCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHEECCCCCCCCCCCCCCCCCC
SEEIYADLEQIHIVACGTSWHAALVGKYLLEQLAGISTQVHYASEYRYAPSPLTANTLII
CHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCEEEE
GVTQSGETADTLAALAMEKERRQGKEAKYQARLLGITNRPESSLGHLVPHIINTLAGIEI
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCHH
GVAATKTFVAQLMAFYALALDLAYHRQTVAPDKLADIIQGLRQIPKEIEATLERQEKLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVP
HHHHHHHCCCCEEEEECCCCCCEEECCCEEEHHEEEEECCCCCCCCCCCCCEEEEECCCC
VVAIAYPGSVYEKVISNSQEAKARDSRLIGVTPVNDGEAAEIFNDLLPVSSVDELLSPIL
EEEEECCHHHHHHHHCCCHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHH
TVVPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYIGTQAATEILLAGLEKLEYRGYDSAGIATVWEGDVNCVRAKGKLHNLRSKLEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEHHHHHHHHHHHHHH
LATPSQIGIGHTRWATHGKPEEYNAHPHLDTAMRIAVVQNGIIENYRELRDELKQKGHEF
HCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSETDTEVIPHLIAEFLKNLPSPALPTSSSSLLEAIRQAVNHLQGAFAIAVISADYPDEL
HCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCE
IVVRQQAPLVIGFGQGEFFCASDTPAIVSHTRAVLPLENGEIARLTPLGVEIYNFAGDRL
EEEEECCCEEEEECCCCEEECCCCCHHHHCCEEEEEECCCCEEEEEECCEEHHHCCCHHH
KKQPRLLNLNPTMVEKQGFKHFMLKEIYEQPGVVRASLEAYFNPDTNTDESFTSPVNLGL
HCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHEECCCCCCCCCCCCCCCCCC
SEEIYADLEQIHIVACGTSWHAALVGKYLLEQLAGISTQVHYASEYRYAPSPLTANTLII
CHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCCEEEE
GVTQSGETADTLAALAMEKERRQGKEAKYQARLLGITNRPESSLGHLVPHIINTLAGIEI
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHCCHH
GVAATKTFVAQLMAFYALALDLAYHRQTVAPDKLADIIQGLRQIPKEIEATLERQEKLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAHEFAETQDFIFLGRGINFPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDAKVP
HHHHHHHCCCCEEEEECCCCCCEEECCCEEEHHEEEEECCCCCCCCCCCCCEEEEECCCC
VVAIAYPGSVYEKVISNSQEAKARDSRLIGVTPVNDGEAAEIFNDLLPVSSVDELLSPIL
EEEEECCHHHHHHHHCCCHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHH
TVVPLQLLAYHIAARRGLDVDQPRNLAKSVTVE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA