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The map label for this gene is minD [H]

Identifier: 75909684

GI number: 75909684

Start: 4312212

End: 4313018

Strand: Direct

Name: minD [H]

Synonym: Ava_3478

Alternate gene names: 75909684

Gene position: 4312212-4313018 (Clockwise)

Preceding gene: 161567474

Following gene: 75909685

Centisome position: 67.74

GC content: 47.46

Gene sequence:

>807_bases
ATGACTCGCATTATTGTAATTACCTCCGGTAAAGGAGGGGTGGGTAAAACTACAGTTTCGGCAAACTTGGGGATGGCCTT
AGCCAAAATGGGTCGTCAAGTCGCCCTAGTAGATGCGGATTTTGGTCTAAGGAATTTGGATTTGCTACTAGGGCTAGAAA
ATCGCATTGTCTATACGGCAGTGGAAGTTCTTTCTAGAGAATGTCGCTTAGAACAAGCATTAGTCAAAGATAAGCGCCAG
CCTAACCTCGTCCTCTTACCAGCAGCCCAAAACCGGACAAAAGATGCAGTAACGCCCGAACAGATGAAGTTATTGGTGAA
CGCCCTGGCGCAAAAGTACCAGTATGTGATCATCGATAGCCCAGCTGGTATTGAAAACGGCTTTAAAAATGCGATCGCCC
CAGCAAAAGAAGCTCTCATTGTCACCACCCCAGAAATTTCCGCCGTGCGTGATGCTGATAGGGTCGTTGGCTTACTCGAA
GCCCAAGGCGTTAAGCGCGTTCACTTGATTATTAACCGGATCAGACCAGCAATGGTTCGGGCAAATGATATGATGTCTGT
TCAAGATGTTCAGGAACTTCTGGCAATACCCTTGATTGGGGTACTTCCTGATGATGAGCGTGTTATTGTCTCCACCAATC
GCGGCGAACCTCTGGTATTAGGAGATACTCCTTCCCTAGCCGCCGTAGCCGTTGAAAATATTGCTCGCAGATTGGAAGGA
GATACAGTTGAATTTCTCGACCTTGACGCACCCCACGATAGCATCTTCGCTCGTTTGCGGAGGTTGTTATGGACTAAGAT
TGTGTAA

Upstream 100 bases:

>100_bases
CAGAGCTACTGATTTTTCCAGAAACCAAATAAGTAAGATCAATCAGACACCATAAATATTTAAGATATTTGTCTAACCAT
AAATCCAGCACATAGTTATC

Downstream 100 bases:

>100_bases
CCTACTTTCCAATCTCTGCATACTTAATTGGCAATGATCCTCGAATTATTAGACAAACTTTTTTTACGTACTCCCGACAC
CAGTCGTTCTCACGTCAAAC

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTRIIVITSGKGGVGKTTVSANLGMALAKMGRQVALVDADFGLRNLDLLLGLENRIVYTAVEVLSRECRLEQALVKDKRQ
PNLVLLPAAQNRTKDAVTPEQMKLLVNALAQKYQYVIIDSPAGIENGFKNAIAPAKEALIVTTPEISAVRDADRVVGLLE
AQGVKRVHLIINRIRPAMVRANDMMSVQDVQELLAIPLIGVLPDDERVIVSTNRGEPLVLGDTPSLAAVAVENIARRLEG
DTVEFLDLDAPHDSIFARLRRLLWTKIV

Sequences:

>Translated_268_residues
MTRIIVITSGKGGVGKTTVSANLGMALAKMGRQVALVDADFGLRNLDLLLGLENRIVYTAVEVLSRECRLEQALVKDKRQ
PNLVLLPAAQNRTKDAVTPEQMKLLVNALAQKYQYVIIDSPAGIENGFKNAIAPAKEALIVTTPEISAVRDADRVVGLLE
AQGVKRVHLIINRIRPAMVRANDMMSVQDVQELLAIPLIGVLPDDERVIVSTNRGEPLVLGDTPSLAAVAVENIARRLEG
DTVEFLDLDAPHDSIFARLRRLLWTKIV
>Mature_267_residues
TRIIVITSGKGGVGKTTVSANLGMALAKMGRQVALVDADFGLRNLDLLLGLENRIVYTAVEVLSRECRLEQALVKDKRQP
NLVLLPAAQNRTKDAVTPEQMKLLVNALAQKYQYVIIDSPAGIENGFKNAIAPAKEALIVTTPEISAVRDADRVVGLLEA
QGVKRVHLIINRIRPAMVRANDMMSVQDVQELLAIPLIGVLPDDERVIVSTNRGEPLVLGDTPSLAAVAVENIARRLEGD
TVEFLDLDAPHDSIFARLRRLLWTKIV

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=258, Percent_Identity=24.8062015503876, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787423, Length=268, Percent_Identity=43.6567164179104, Blast_Score=219, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24667611, Length=226, Percent_Identity=28.3185840707965, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29263; Mature: 29132

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRIIVITSGKGGVGKTTVSANLGMALAKMGRQVALVDADFGLRNLDLLLGLENRIVYTA
CEEEEEEECCCCCCCCEEEECHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCHHHHHH
VEVLSRECRLEQALVKDKRQPNLVLLPAAQNRTKDAVTPEQMKLLVNALAQKYQYVIIDS
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEC
PAGIENGFKNAIAPAKEALIVTTPEISAVRDADRVVGLLEAQGVKRVHLIINRIRPAMVR
CCCCCCCHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ANDMMSVQDVQELLAIPLIGVLPDDERVIVSTNRGEPLVLGDTPSLAAVAVENIARRLEG
HCCCCCHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCC
DTVEFLDLDAPHDSIFARLRRLLWTKIV
CCEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRIIVITSGKGGVGKTTVSANLGMALAKMGRQVALVDADFGLRNLDLLLGLENRIVYTA
EEEEEEECCCCCCCCEEEECHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCHHHHHH
VEVLSRECRLEQALVKDKRQPNLVLLPAAQNRTKDAVTPEQMKLLVNALAQKYQYVIIDS
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCEEEEEEEC
PAGIENGFKNAIAPAKEALIVTTPEISAVRDADRVVGLLEAQGVKRVHLIINRIRPAMVR
CCCCCCCHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ANDMMSVQDVQELLAIPLIGVLPDDERVIVSTNRGEPLVLGDTPSLAAVAVENIARRLEG
HCCCCCHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCC
DTVEFLDLDAPHDSIFARLRRLLWTKIV
CCEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]