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The map label for this gene is ubiB [C]

Identifier: 75909587

GI number: 75909587

Start: 4203221

End: 4204957

Strand: Direct

Name: ubiB [C]

Synonym: Ava_3381

Alternate gene names: 75909587

Gene position: 4203221-4204957 (Clockwise)

Preceding gene: 75909586

Following gene: 75909588

Centisome position: 66.03

GC content: 44.73

Gene sequence:

>1737_bases
GTGTCTTTTCTTCCAGGTGATTCAGTAATAACCCAACGGTACGCGCAAGATATGGAAACCAATTATTCAGATAAGGCTTA
CCGTTGGAATCGGGAAAACTACTCTAGCAAGCGGCGCTTTGTGGACATTTGGTCTTTTGTCTTGACCTTAATGTTCAAGC
TTTGGCGCTACAACAAATCTTGGAGTTATCCTGGCGGTGTCACGGAAGCAAAACAGGCTGCAAGACGTAAAGCTCAAGCA
GTCTGGATTCGTAATACTCTGCTGGATTTGGGGCCAACCTTCATTAAAGTCGGGCAGCTATTTTCTACCCGTGCAGATAT
ATTCCCTGGCGAATATGTAGAAGAGTTGGCAAAGCTACAAGACAAAGTGCCAGCATTTGGCTATGAGCAAGTTGAAAAAA
TAGTTGAGCAAGAATTAGGTAAAAAAATTCCCGAACTCTTTCACAGTTTTGAGCCAATCCCTCTAGCCGCAGCTAGTTTG
GGACAAGTACACAAGGCTGTATTGCATAGTGGGGAATCTGTCGTTGTTAAAGTACAGCGACCAGGATTAAAAAAGTTATT
TGAGATAGATTTACGAATTCTTAAAGGCATTGCCCGTTACTTTCAAAGCCATCCCAAATGGGGACGAGGACGGGATTGGA
TGGGGATTTACGAAGAATGTTGCCGGATTCTTTGGGAAGAGATTGACTATCTCAACGAAGGTCGCAACGCCGACACTTTT
CGGCGGAACTTTCGCGGCTATGAATGGGTAAAAGTCCCCAAGGTTTATTGGCGTTATGCTTCGCCACGGGTATTAACTTT
GGAGTACCTACCAGGGATCAAAATCAGCCAATATGAAGCCATAGAAGCCGCAGGATTAGACCGGAAGGTCTTGGCTCGTC
AAGGCGCTCAAGCCTACCTATTGCAACTGCTCAATAACGGATTTTTCCATGCCGATCCCCATCCAGGTAATATTGCGGTT
AGTGCCGATGGAGCCTTAATCTTCTATGACTTCGGTATGATGGGGCAGATTAAATCAAATATCCGCGAAGGGCTAATGCA
AACGTTGTTTGGTATCGCTCAAAAAGATGGCGATCGCGTAGTCCAGTCTCTCATAGATTTGGGAGCGATCGCACCCGTAG
ATGATATGGGGCCAGTGCGGCGTTCGGTGCAGTATATGCTCGACAACTTCATGGATAAACCCTTTGAAAATCAATCTGTA
GCCGCGATTAGTGATGATTTATACGAAATAGCTTATAATCAACCATTTAGATTTCCTGCAACTTTCACTTTTGTGATGCG
TGCTTTTTCCACCCTTGAAGGGGTAGGCAAAGGGTTAGATCCAGAGTTTAACTTTATGGAAGTTGCCCAACCATACGCAA
TGCAGCTTATGACCGATATGAATGGTTCAGATAGCAACAGCTTCCTCAACGAATTGAGCCGACAAGCAGTCCAAGTCAGT
ACCACGGCTTTTGGATTACCACGGAGATTGGAAGATACACTAGAAAAATTAGAGCGGGGAGATATGCGCTTGCGGGTACG
TTCTATAGAATCAGAACGACTCCTCCGGCGACAAGGCAATATTCAGATAGGCATAGGTTATGCACTGATAATCAGTGGAT
TTACCCTTTCAGCAACTATTTTGTTAGTTAATCATTATGTATGGTTAGCACTGCTGGCTGGTTTAATTGCCGCAGCAGTG
TCAGTAATGCTGATTCGACTGCTTCTCCGCCTAGATCGTTATGACCGTATGTATTAA

Upstream 100 bases:

>100_bases
ACTGCTGTTAGCGTAGCGGTAGCGACATTAGGAGCGTCACCCCTAAGGGTCAGTCGTTCATTGGCAAATGGCAATTTAGG
AAAACAATTTAGGGATCAGA

Downstream 100 bases:

>100_bases
TTGTTGTGATAAAAAGTTATGAAACTCAACTTCACGGGTCACACTGATCCGGGGCTTATTCGTTCTAATAATCAGGATGA
TTACTATATCGACCCTGAGG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MSFLPGDSVITQRYAQDMETNYSDKAYRWNRENYSSKRRFVDIWSFVLTLMFKLWRYNKSWSYPGGVTEAKQAARRKAQA
VWIRNTLLDLGPTFIKVGQLFSTRADIFPGEYVEELAKLQDKVPAFGYEQVEKIVEQELGKKIPELFHSFEPIPLAAASL
GQVHKAVLHSGESVVVKVQRPGLKKLFEIDLRILKGIARYFQSHPKWGRGRDWMGIYEECCRILWEEIDYLNEGRNADTF
RRNFRGYEWVKVPKVYWRYASPRVLTLEYLPGIKISQYEAIEAAGLDRKVLARQGAQAYLLQLLNNGFFHADPHPGNIAV
SADGALIFYDFGMMGQIKSNIREGLMQTLFGIAQKDGDRVVQSLIDLGAIAPVDDMGPVRRSVQYMLDNFMDKPFENQSV
AAISDDLYEIAYNQPFRFPATFTFVMRAFSTLEGVGKGLDPEFNFMEVAQPYAMQLMTDMNGSDSNSFLNELSRQAVQVS
TTAFGLPRRLEDTLEKLERGDMRLRVRSIESERLLRRQGNIQIGIGYALIISGFTLSATILLVNHYVWLALLAGLIAAAV
SVMLIRLLLRLDRYDRMY

Sequences:

>Translated_578_residues
MSFLPGDSVITQRYAQDMETNYSDKAYRWNRENYSSKRRFVDIWSFVLTLMFKLWRYNKSWSYPGGVTEAKQAARRKAQA
VWIRNTLLDLGPTFIKVGQLFSTRADIFPGEYVEELAKLQDKVPAFGYEQVEKIVEQELGKKIPELFHSFEPIPLAAASL
GQVHKAVLHSGESVVVKVQRPGLKKLFEIDLRILKGIARYFQSHPKWGRGRDWMGIYEECCRILWEEIDYLNEGRNADTF
RRNFRGYEWVKVPKVYWRYASPRVLTLEYLPGIKISQYEAIEAAGLDRKVLARQGAQAYLLQLLNNGFFHADPHPGNIAV
SADGALIFYDFGMMGQIKSNIREGLMQTLFGIAQKDGDRVVQSLIDLGAIAPVDDMGPVRRSVQYMLDNFMDKPFENQSV
AAISDDLYEIAYNQPFRFPATFTFVMRAFSTLEGVGKGLDPEFNFMEVAQPYAMQLMTDMNGSDSNSFLNELSRQAVQVS
TTAFGLPRRLEDTLEKLERGDMRLRVRSIESERLLRRQGNIQIGIGYALIISGFTLSATILLVNHYVWLALLAGLIAAAV
SVMLIRLLLRLDRYDRMY
>Mature_577_residues
SFLPGDSVITQRYAQDMETNYSDKAYRWNRENYSSKRRFVDIWSFVLTLMFKLWRYNKSWSYPGGVTEAKQAARRKAQAV
WIRNTLLDLGPTFIKVGQLFSTRADIFPGEYVEELAKLQDKVPAFGYEQVEKIVEQELGKKIPELFHSFEPIPLAAASLG
QVHKAVLHSGESVVVKVQRPGLKKLFEIDLRILKGIARYFQSHPKWGRGRDWMGIYEECCRILWEEIDYLNEGRNADTFR
RNFRGYEWVKVPKVYWRYASPRVLTLEYLPGIKISQYEAIEAAGLDRKVLARQGAQAYLLQLLNNGFFHADPHPGNIAVS
ADGALIFYDFGMMGQIKSNIREGLMQTLFGIAQKDGDRVVQSLIDLGAIAPVDDMGPVRRSVQYMLDNFMDKPFENQSVA
AISDDLYEIAYNQPFRFPATFTFVMRAFSTLEGVGKGLDPEFNFMEVAQPYAMQLMTDMNGSDSNSFLNELSRQAVQVST
TAFGLPRRLEDTLEKLERGDMRLRVRSIESERLLRRQGNIQIGIGYALIISGFTLSATILLVNHYVWLALLAGLIAAAVS
VMLIRLLLRLDRYDRMY

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=283, Percent_Identity=31.8021201413428, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI41393593, Length=296, Percent_Identity=32.7702702702703, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI217035081, Length=281, Percent_Identity=30.6049822064057, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI32261307, Length=318, Percent_Identity=23.5849056603774, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI27363457, Length=296, Percent_Identity=26.0135135135135, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI217416386, Length=239, Percent_Identity=26.3598326359833, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI34147522, Length=211, Percent_Identity=27.9620853080569, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI2367309, Length=520, Percent_Identity=28.6538461538462, Blast_Score=206, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17559152, Length=259, Percent_Identity=31.2741312741313, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17555620, Length=487, Percent_Identity=23.2032854209446, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565180, Length=262, Percent_Identity=27.8625954198473, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=264, Percent_Identity=28.4090909090909, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6325148, Length=492, Percent_Identity=22.1544715447154, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=252, Percent_Identity=28.968253968254, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI22024280, Length=332, Percent_Identity=32.5301204819277, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24662575, Length=287, Percent_Identity=36.5853658536585, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI18859849, Length=273, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 66184; Mature: 66053

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFLPGDSVITQRYAQDMETNYSDKAYRWNRENYSSKRRFVDIWSFVLTLMFKLWRYNKS
CCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
WSYPGGVTEAKQAARRKAQAVWIRNTLLDLGPTFIKVGQLFSTRADIFPGEYVEELAKLQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
DKVPAFGYEQVEKIVEQELGKKIPELFHSFEPIPLAAASLGQVHKAVLHSGESVVVKVQR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
PGLKKLFEIDLRILKGIARYFQSHPKWGRGRDWMGIYEECCRILWEEIDYLNEGRNADTF
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHH
RRNFRGYEWVKVPKVYWRYASPRVLTLEYLPGIKISQYEAIEAAGLDRKVLARQGAQAYL
HHHCCCCCEEECCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHHHCCHHHHH
LQLLNNGFFHADPHPGNIAVSADGALIFYDFGMMGQIKSNIREGLMQTLFGIAQKDGDRV
HHHHHCCCEECCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
VQSLIDLGAIAPVDDMGPVRRSVQYMLDNFMDKPFENQSVAAISDDLYEIAYNQPFRFPA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCH
TFTFVMRAFSTLEGVGKGLDPEFNFMEVAQPYAMQLMTDMNGSDSNSFLNELSRQAVQVS
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TTAFGLPRRLEDTLEKLERGDMRLRVRSIESERLLRRQGNIQIGIGYALIISGFTLSATI
HHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCEEEEEHHHHHHCCHHHHHHH
LLVNHYVWLALLAGLIAAAVSVMLIRLLLRLDRYDRMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]