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The map label for this gene is suhB [H]

Identifier: 75909539

GI number: 75909539

Start: 4152590

End: 4153396

Strand: Direct

Name: suhB [H]

Synonym: Ava_3333

Alternate gene names: 75909539

Gene position: 4152590-4153396 (Clockwise)

Preceding gene: 75909538

Following gene: 75909540

Centisome position: 65.23

GC content: 45.48

Gene sequence:

>807_bases
ATGAATGATTTTTGGACGACAATTCTCGATTTTGCCGAAACTACCACCACCAGAGTGGGCGCGCGATTAATGCAGGATTT
TGGGCAAGTGCAGGCTTTACAAAAAGCTGACGGTAGCTTGGTAACCCAAGCTGATAAATGGGCAGATCAAGAAATTCGAG
ATGCGATCGCCTCTACTTTTTCTGGTTACGGAATTTTAACTGAAGAAAGCGAACGCACATTTCCTGGGACAGAGTGGTGC
TGGGTCATCGATCCTTTAGATGGGACAACGAACTTTACACGGGGTATTCCCATCTGGTCGATTTCTCTGGCTTTGCTTTA
CCGAGGGACACCGATTTTTGGTTATGTTTATGCGCCACCCCTCAATCAAGCTTTTCATGGTTTCTGGCCAGGTACATCTG
GTTTAAGCACACCCTCTGGGGCATTTCTCAATCATCACCCAATTCATACCAGTAGTGACGCTCCCAGCAGCAATCACTTT
TTTAACCTTTGTTCCCGCAGTTTAGCTGTTGTTCAGAACGGATTTCCCTGCAAAATTCGGATGCTGGGTGTAGCTAGTTA
CAACTTCCTTACGGTGGCGGCTGGCGCAACATTAGGAGGAATAGAAGCAACACCAAAAGTTTGGGACATAGCAGGCGCTT
GGGTAATTGTCCAAGCTGCTGGTGGTAGCTGGGTTTCCCTCGACTCAGAACCATTTCCCTTATCAAATGGGGAAGATTAT
AGCGATCGCTCTTTCCCTACTCTCGTTGTTAGTCGTTCAGACTTAGTTACATTTTTTACACCTCTAATTAAAGATGTAAA
AATTTAA

Upstream 100 bases:

>100_bases
AAAGTGATTTATAGCTGTTGTCAGTAGTGTTAAGACATCGATAGATTATACAACCCAATCCCCAATCCCCAGCCATAGAT
TAGAACGTGAGAATTTATTG

Downstream 100 bases:

>100_bases
CTCACTACATACTTTTTTATCAACCCAGGTTGCCTGTAATCACAAAAAATTTTACAGGCGACCTGGGTAATTTTTCTGGA
TATGAGATTTTTTCAACGTA

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNDFWTTILDFAETTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEPFPLSNGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI

Sequences:

>Translated_268_residues
MNDFWTTILDFAETTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEPFPLSNGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
>Mature_268_residues
MNDFWTTILDFAETTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTFSGYGILTEESERTFPGTEWC
WVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPPLNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHF
FNLCSRSLAVVQNGFPCKIRMLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEPFPLSNGEDY
SDRSFPTLVVSRSDLVTFFTPLIKDVKI

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=25.296442687747, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=25.296442687747, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1788882, Length=243, Percent_Identity=29.6296296296296, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193202572, Length=217, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=222, Percent_Identity=27.4774774774775, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320493, Length=222, Percent_Identity=30.6306306306306, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357329, Length=276, Percent_Identity=27.8985507246377, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24664926, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24664922, Length=243, Percent_Identity=26.3374485596708, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29228; Mature: 29228

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDFWTTILDFAETTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHH
SGYGILTEESERTFPGTEWCWVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPP
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHEEEHEECCCCEEEEEECCC
LNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHFFNLCSRSLAVVQNGFPCKIR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEPFPLSNGEDY
EEEEECCCEEEEECCCEECCCCCCCCEEEECCEEEEEEECCCCEEEECCCCCCCCCCCCC
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
CCCCCCEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDFWTTILDFAETTTTRVGARLMQDFGQVQALQKADGSLVTQADKWADQEIRDAIASTF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHH
SGYGILTEESERTFPGTEWCWVIDPLDGTTNFTRGIPIWSISLALLYRGTPIFGYVYAPP
CCCEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHEEEHEECCCCEEEEEECCC
LNQAFHGFWPGTSGLSTPSGAFLNHHPIHTSSDAPSSNHFFNLCSRSLAVVQNGFPCKIR
CCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEE
MLGVASYNFLTVAAGATLGGIEATPKVWDIAGAWVIVQAAGGSWVSLDSEPFPLSNGEDY
EEEEECCCEEEEECCCEECCCCCCCCEEEECCEEEEEEECCCCEEEECCCCCCCCCCCCC
SDRSFPTLVVSRSDLVTFFTPLIKDVKI
CCCCCCEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]