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The map label for this gene is frpC [H]

Identifier: 75909367

GI number: 75909367

Start: 3922446

End: 3924017

Strand: Direct

Name: frpC [H]

Synonym: Ava_3160

Alternate gene names: 75909367

Gene position: 3922446-3924017 (Clockwise)

Preceding gene: 75909363

Following gene: 75909368

Centisome position: 61.62

GC content: 41.48

Gene sequence:

>1572_bases
ATGTCAGCAATCCAACTTTCTAGCATCCTCAATAATAATGTTTATACTGAAAACTTTAATACCTTACGTACTTCAGGTAA
CGCCACTTGGGTTAATGACAGCACTATTAATGGATGGTACACAGCTCGTACTGGTACTGGAACCCAAATTTCTACAACTA
ATGGCAGCACTAGTACTGGAAACTTATACAGTTTTGGTACTGTAGGTAGCACCGATCGCGCCTTAGGTTCCATCGGTTCA
AGTGGCTCCAGCGCCGGAAGTTTTTTCTGGGGTGTCCGCTTAGTTAATAATACAAACATCACCCTCGATTTTCTTAAAAT
CAGTTATGTCGGTGAACAATGGCGTAATAGCGGTGCAGGCGCTCAGACAGTAGATTTTCAGTATCAAGTCGGTGCTACTA
GTATCACTGGCGGTACTTGGATAGATGCTAATAACCTTGACTTTACCAGTCCAGTAACTGGTGGTACTGCAACGGCTCTA
GATGGTAATGCAGCAGCTAACCGTACTTCTATATCCGGTAAAATCAGTGGTCTGAATCTAGCACCAGGCCAAGAAATCTG
GCTACGTTGGCGCGACATCGACCATACAGGTAGTGATCATGGTCTAGCCATTGATGACTTTTCTTTATCATTTGGTACTT
TTGGTACAAACGGCAACGATACTCTACAAGGTGATGACTCTGAAGACTATATAGACGGTTTAGCCGGTAACGACATCATC
ACAGGATTAAAGGGAGATGACATCCTCATAGGTGGTGGTGGTAATGATCAGTTCATCCTTAATGCAGGAGACGGAACAGA
TACCATCACTGATTTTGGTGGTGCAGGTACTCGCTTTAATCCATCCTCCAGTATCCGAGCAGAAATGGATCTCTTGAAAT
TTCAAGGCGCTGGTATGACTGCTCAAAATATGCTCCTCACCCAAAATGGTGCTAATTTAGAAATTACCTTCGAGGGTGTG
GCTAATACCAAGGTCATTTTGCAGAATTTTCAGATGCAAAACCTGAATAACTTCCGGGAACCGCTCCTCAGTCAGCCGAA
GATAGGCAACATTCTGTTTGAAGGAGACGGTAACACTATTCAAGATGTCTATGATGTTTACACTGCTACCCAAACCGACA
GAACCAACTTTAAAAATAATGCTGTCACTTTCCTGAATGACCTTGATAACTACTACGTTGGTCTCAATGGTTCTAACGAT
GTTATTAATGGTCAAGGAGGTAACGACACAATTGATGGTTTAAGTGGTAATGACATCCTCCGGGGTGGAGATGGTAATGA
TATTCTCATTGGTGGATTGGGTAATGATATTTTAGTTGGTGGTAGTGGTAATGACCTATTTGTTCTACAAGCAAAGGGTG
GAACAGATATAATCAAAGACTTTGTAGACGGTCAAGACTTGATTGGTTTAGCAGGTGGTTTGACCTTTGGACAATTAACC
ATCACTCAAGGTACGGGTGTAGATATTAATAATACTTTAATTAGAATCACTAGTACCAATGAATTAATAGGTATCTTAAA
TGGAGTTGTCAGCAGTAATATTACTGTCAGTGATTTCACTGCATTTACTTAA

Upstream 100 bases:

>100_bases
TTACAGTAAATTAATCTATCTATGAATTTAAATACACAATCAATGAGATTTTCTGTAAATAAATTGACTAACCAAAAACA
ACAATATCCCAGGTTTTACT

Downstream 100 bases:

>100_bases
ACGTATGAAAGGTTATTTATAAAGTATAAATAAAATTCCTGTAGTGGAGTGTCAAGGCTAAAGTAGTGGAAAAATATAGC
TCTTGTGGGATGGGCTTCTA

Product: hemolysin-type calcium-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MSAIQLSSILNNNVYTENFNTLRTSGNATWVNDSTINGWYTARTGTGTQISTTNGSTSTGNLYSFGTVGSTDRALGSIGS
SGSSAGSFFWGVRLVNNTNITLDFLKISYVGEQWRNSGAGAQTVDFQYQVGATSITGGTWIDANNLDFTSPVTGGTATAL
DGNAAANRTSISGKISGLNLAPGQEIWLRWRDIDHTGSDHGLAIDDFSLSFGTFGTNGNDTLQGDDSEDYIDGLAGNDII
TGLKGDDILIGGGGNDQFILNAGDGTDTITDFGGAGTRFNPSSSIRAEMDLLKFQGAGMTAQNMLLTQNGANLEITFEGV
ANTKVILQNFQMQNLNNFREPLLSQPKIGNILFEGDGNTIQDVYDVYTATQTDRTNFKNNAVTFLNDLDNYYVGLNGSND
VINGQGGNDTIDGLSGNDILRGGDGNDILIGGLGNDILVGGSGNDLFVLQAKGGTDIIKDFVDGQDLIGLAGGLTFGQLT
ITQGTGVDINNTLIRITSTNELIGILNGVVSSNITVSDFTAFT

Sequences:

>Translated_523_residues
MSAIQLSSILNNNVYTENFNTLRTSGNATWVNDSTINGWYTARTGTGTQISTTNGSTSTGNLYSFGTVGSTDRALGSIGS
SGSSAGSFFWGVRLVNNTNITLDFLKISYVGEQWRNSGAGAQTVDFQYQVGATSITGGTWIDANNLDFTSPVTGGTATAL
DGNAAANRTSISGKISGLNLAPGQEIWLRWRDIDHTGSDHGLAIDDFSLSFGTFGTNGNDTLQGDDSEDYIDGLAGNDII
TGLKGDDILIGGGGNDQFILNAGDGTDTITDFGGAGTRFNPSSSIRAEMDLLKFQGAGMTAQNMLLTQNGANLEITFEGV
ANTKVILQNFQMQNLNNFREPLLSQPKIGNILFEGDGNTIQDVYDVYTATQTDRTNFKNNAVTFLNDLDNYYVGLNGSND
VINGQGGNDTIDGLSGNDILRGGDGNDILIGGLGNDILVGGSGNDLFVLQAKGGTDIIKDFVDGQDLIGLAGGLTFGQLT
ITQGTGVDINNTLIRITSTNELIGILNGVVSSNITVSDFTAFT
>Mature_522_residues
SAIQLSSILNNNVYTENFNTLRTSGNATWVNDSTINGWYTARTGTGTQISTTNGSTSTGNLYSFGTVGSTDRALGSIGSS
GSSAGSFFWGVRLVNNTNITLDFLKISYVGEQWRNSGAGAQTVDFQYQVGATSITGGTWIDANNLDFTSPVTGGTATALD
GNAAANRTSISGKISGLNLAPGQEIWLRWRDIDHTGSDHGLAIDDFSLSFGTFGTNGNDTLQGDDSEDYIDGLAGNDIIT
GLKGDDILIGGGGNDQFILNAGDGTDTITDFGGAGTRFNPSSSIRAEMDLLKFQGAGMTAQNMLLTQNGANLEITFEGVA
NTKVILQNFQMQNLNNFREPLLSQPKIGNILFEGDGNTIQDVYDVYTATQTDRTNFKNNAVTFLNDLDNYYVGLNGSNDV
INGQGGNDTIDGLSGNDILRGGDGNDILIGGLGNDILVGGSGNDLFVLQAKGGTDIIKDFVDGQDLIGLAGGLTFGQLTI
TQGTGVDINNTLIRITSTNELIGILNGVVSSNITVSDFTAFT

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 54902; Mature: 54770

Theoretical pI: Translated: 3.87; Mature: 3.87

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIQLSSILNNNVYTENFNTLRTSGNATWVNDSTINGWYTARTGTGTQISTTNGSTSTG
CCCEEEHHHHCCCEEECCCCEEEECCCEEEECCCCCCCEEEEECCCCCEEEECCCCCCCC
NLYSFGTVGSTDRALGSIGSSGSSAGSFFWGVRLVNNTNITLDFLKISYVGEQWRNSGAG
CEEEECCCCCCHHHHHCCCCCCCCCCEEEEEEEEEECCCEEEEEEEEEEECHHHHCCCCC
AQTVDFQYQVGATSITGGTWIDANNLDFTSPVTGGTATALDGNAAANRTSISGKISGLNL
CEEEEEEEEECCEEECCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCEECCEEEECEEC
APGQEIWLRWRDIDHTGSDHGLAIDDFSLSFGTFGTNGNDTLQGDDSEDYIDGLAGNDII
CCCCEEEEEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEE
TGLKGDDILIGGGGNDQFILNAGDGTDTITDFGGAGTRFNPSSSIRAEMDLLKFQGAGMT
ECCCCCEEEEECCCCCEEEEECCCCCCCHHCCCCCCCEECCCCCCHHEEEEEEECCCCCC
AQNMLLTQNGANLEITFEGVANTKVILQNFQMQNLNNFREPLLSQPKIGNILFEGDGNTI
CCCEEEEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCHH
QDVYDVYTATQTDRTNFKNNAVTFLNDLDNYYVGLNGSNDVINGQGGNDTIDGLSGNDIL
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEE
RGGDGNDILIGGLGNDILVGGSGNDLFVLQAKGGTDIIKDFVDGQDLIGLAGGLTFGQLT
ECCCCCEEEEEECCCEEEEECCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCEEEEEE
ITQGTGVDINNTLIRITSTNELIGILNGVVSSNITVSDFTAFT
EECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCEEECCEEECC
>Mature Secondary Structure 
SAIQLSSILNNNVYTENFNTLRTSGNATWVNDSTINGWYTARTGTGTQISTTNGSTSTG
CCEEEHHHHCCCEEECCCCEEEECCCEEEECCCCCCCEEEEECCCCCEEEECCCCCCCC
NLYSFGTVGSTDRALGSIGSSGSSAGSFFWGVRLVNNTNITLDFLKISYVGEQWRNSGAG
CEEEECCCCCCHHHHHCCCCCCCCCCEEEEEEEEEECCCEEEEEEEEEEECHHHHCCCCC
AQTVDFQYQVGATSITGGTWIDANNLDFTSPVTGGTATALDGNAAANRTSISGKISGLNL
CEEEEEEEEECCEEECCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCEECCEEEECEEC
APGQEIWLRWRDIDHTGSDHGLAIDDFSLSFGTFGTNGNDTLQGDDSEDYIDGLAGNDII
CCCCEEEEEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEE
TGLKGDDILIGGGGNDQFILNAGDGTDTITDFGGAGTRFNPSSSIRAEMDLLKFQGAGMT
ECCCCCEEEEECCCCCEEEEECCCCCCCHHCCCCCCCEECCCCCCHHEEEEEEECCCCCC
AQNMLLTQNGANLEITFEGVANTKVILQNFQMQNLNNFREPLLSQPKIGNILFEGDGNTI
CCCEEEEECCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCHH
QDVYDVYTATQTDRTNFKNNAVTFLNDLDNYYVGLNGSNDVINGQGGNDTIDGLSGNDIL
HHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCEEECCCCCCCCCCCCCCCEE
RGGDGNDILIGGLGNDILVGGSGNDLFVLQAKGGTDIIKDFVDGQDLIGLAGGLTFGQLT
ECCCCCEEEEEECCCEEEEECCCCEEEEEEECCCHHHHHHHCCCCCEEEEECCCEEEEEE
ITQGTGVDINNTLIRITSTNELIGILNGVVSSNITVSDFTAFT
EECCCCCCCCCCEEEEECCCHHHHHHHHHHHCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]