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The map label for this gene is luxQ [H]

Identifier: 75909218

GI number: 75909218

Start: 3732320

End: 3734131

Strand: Direct

Name: luxQ [H]

Synonym: Ava_3009

Alternate gene names: 75909218

Gene position: 3732320-3734131 (Clockwise)

Preceding gene: 75909216

Following gene: 75909219

Centisome position: 58.63

GC content: 41.11

Gene sequence:

>1812_bases
ATGCAGCAGTATTCAAGCTTACCAGAACACAACTCATCGATAGACACAACGCCGACTCTGTTGGCAAAAAGTCAGCAGCT
TTGCGCTGAGTTATGGCTGGAACGCAGCTTGAACCAGCTACAAACACGCCTGCTTAATTGCTTAGAGTCTGCTTTCAACA
GTGTTCCCACAAGAACCACAGAAGCGGATATTTTCCAAACAGTGGTTAATGAACTAGACATTGCTTTAAACAATAGCAAT
GTGGGTTTTCCTTTGTGTGCTGTGGGGATTGCTCTGTTGCAACCGCAAGCAGCAGTTGGTAAAGTTTACTATATTTCTCG
CCCTCTATCTCTAGGCTGTCAACCTCCACTCTTAGAAGAAATATCCAAAGACGGGAAAAAACTGCGGTTGCAATTGCAAG
AAGCGATCAAAATTACAGATTTACAAAAACTAGAAAAGCAACAACCTCCACAAGCTTGGCAATTAAGGGATGATGCTGAT
GGTGTGATCGGGTGGTTACTTCTGGCGACAGATAACTCAAAGCCTCATGAAAACGCATTCACAGCACCACATCCTCAACT
TAATACGCAACTCATGGAGCGATCGGCCGAACAATGTGTGAAAGCCTTAGCACATCTCAAAAAAATACAATCTTTGCAGC
AGAAATCTCAAAATTTAGGTATTTCTAATCAGGAATTGGAGCGGACTAATCAACTGAAAAATCAGTTTTTAGCCAATACA
AGTCATGAAATTCGCACACCCCTAAGTTCGATTATTGGTTTTACTCACCTGCTTCTAGCGCAAGGTTACGATCCAACGAG
AGAGCGCCATCATGAATATTTAAATATTATTCAATCTAGTGGTAAACATCTATTGGCTCTGATTAACGATATTTTGGATC
TCTCCAAGATTGAGGCTAATCAGTTAGAAGTACAGTGGGAAAAGGTGAATGTACCAGAACTTTGTCAAAATGTATTAACG
CTGATCAAGGAGAAGGCCGCAAATAAAGGGGTGAAATTGTCTTTGGAATTAGATCCCCATATCAAGACTTTTGTTGCTGA
CCCTTTGCGGCTCAAACAGATGCTTTTGAACTTGTTATTTAATGCTCTCAAATTTACTAATCAAGGCACTGTTGGCTTAA
AGGTGACACAGCGAGAGTCATTTATCCACTTTACAGTCTGGGACACTGGTAGCGGTATTTCTCCAGAAAATCTGGCGCTA
CTGTTTCAACCATATTTCCAAATTCCTAATTCTTCAGTTGCCCAACATGAAGGTACTGGTTTAGGTTTAGTGGTGACTCG
TAAACTGGCAGAAATTCACAATGGTTCTGTAGAAGTAGAATCCCAAGTTGATCACGGTTCCCGCTTCACTATTATCTTGC
CTCTACAACAGAATGGGCAAGTATTAGTAGGAGAAGATATGGAGGATGAGGAAACGACATCTCCTGCATCTTTGACACCT
AACAGTTCAAAAGACATTTTGTTAGTTGAGGATGATTTACCCAACGGTGAATTGATGCAAACTCACTTGTCTAAGTTGGG
ATATAACGTTACTTGGGTCAAGAATGCCCATGAAATGTGGGCAAAACTAGACCAACAACAAGCAGCAGTTATCTTAATGG
ATATCCGGTTACCAGATGGTGATGGTTTAGATTTAGTCAAGCAGTTGCGAGAAAAATCTCAATATCAACAGATTCCTATT
ATTGCCCAAACAGCGATGGCGATGAAAGGCGATCGCTCTATCTGTCTATCTGCTGGAGTCAACGACTATATTTCTAAACC
CATAGATTTAAATCTTTTGGCCAGTCTGGTGGCTAAGTATAGTCAGCTTTAG

Upstream 100 bases:

>100_bases
AAGTTATGATTTATCGACAAAAAAGAATTGTGAGCTAATATACATAGAATCGTGTTTGCATTTTTTGCAAAACTAAAGTT
GTTAAACGGTCTAGTTGACC

Downstream 100 bases:

>100_bases
GGATTGGGGACTGGGGACTGGGAGGAAGGACTAATTACCACTGACAACTGACAACCGACAACTGACAACTAACAACTGAC
CAATGATTAAAATATTGCTA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLESAFNSVPTRTTEADIFQTVVNELDIALNNSN
VGFPLCAVGIALLQPQAAVGKVYYISRPLSLGCQPPLLEEISKDGKKLRLQLQEAIKITDLQKLEKQQPPQAWQLRDDAD
GVIGWLLLATDNSKPHENAFTAPHPQLNTQLMERSAEQCVKALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANT
SHEIRTPLSSIIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEANQLEVQWEKVNVPELCQNVLT
LIKEKAANKGVKLSLELDPHIKTFVADPLRLKQMLLNLLFNALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLAL
LFQPYFQIPNSSVAQHEGTGLGLVVTRKLAEIHNGSVEVESQVDHGSRFTIILPLQQNGQVLVGEDMEDEETTSPASLTP
NSSKDILLVEDDLPNGELMQTHLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDGDGLDLVKQLREKSQYQQIPI
IAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKYSQL

Sequences:

>Translated_603_residues
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLESAFNSVPTRTTEADIFQTVVNELDIALNNSN
VGFPLCAVGIALLQPQAAVGKVYYISRPLSLGCQPPLLEEISKDGKKLRLQLQEAIKITDLQKLEKQQPPQAWQLRDDAD
GVIGWLLLATDNSKPHENAFTAPHPQLNTQLMERSAEQCVKALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANT
SHEIRTPLSSIIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEANQLEVQWEKVNVPELCQNVLT
LIKEKAANKGVKLSLELDPHIKTFVADPLRLKQMLLNLLFNALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLAL
LFQPYFQIPNSSVAQHEGTGLGLVVTRKLAEIHNGSVEVESQVDHGSRFTIILPLQQNGQVLVGEDMEDEETTSPASLTP
NSSKDILLVEDDLPNGELMQTHLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDGDGLDLVKQLREKSQYQQIPI
IAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKYSQL
>Mature_603_residues
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLESAFNSVPTRTTEADIFQTVVNELDIALNNSN
VGFPLCAVGIALLQPQAAVGKVYYISRPLSLGCQPPLLEEISKDGKKLRLQLQEAIKITDLQKLEKQQPPQAWQLRDDAD
GVIGWLLLATDNSKPHENAFTAPHPQLNTQLMERSAEQCVKALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANT
SHEIRTPLSSIIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEANQLEVQWEKVNVPELCQNVLT
LIKEKAANKGVKLSLELDPHIKTFVADPLRLKQMLLNLLFNALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLAL
LFQPYFQIPNSSVAQHEGTGLGLVVTRKLAEIHNGSVEVESQVDHGSRFTIILPLQQNGQVLVGEDMEDEETTSPASLTP
NSSKDILLVEDDLPNGELMQTHLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDGDGLDLVKQLREKSQYQQIPI
IAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKYSQL

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=377, Percent_Identity=34.7480106100796, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI48994928, Length=381, Percent_Identity=32.0209973753281, Blast_Score=178, Evalue=7e-46,
Organism=Escherichia coli, GI87081816, Length=451, Percent_Identity=30.3769401330377, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1789149, Length=284, Percent_Identity=34.1549295774648, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=33.976833976834, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.3418803418803, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=29.9559471365639, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=29.4871794871795, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=30.379746835443, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.8701298701299, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=26.9565217391304, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=28.3898305084746, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1790300, Length=250, Percent_Identity=26, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789809, Length=114, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787894, Length=252, Percent_Identity=26.5873015873016, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789402, Length=105, Percent_Identity=34.2857142857143, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=112, Percent_Identity=33.0357142857143, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=232, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=87, Percent_Identity=41.3793103448276, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67250; Mature: 67250

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLESAFNSVPTRTT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EADIFQTVVNELDIALNNSNVGFPLCAVGIALLQPQAAVGKVYYISRPLSLGCQPPLLEE
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCHHHCEEEEEECCCCCCCCCHHHHH
ISKDGKKLRLQLQEAIKITDLQKLEKQQPPQAWQLRDDADGVIGWLLLATDNSKPHENAF
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
TAPHPQLNTQLMERSAEQCVKALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SHEIRTPLSSIIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEAN
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
QLEVQWEKVNVPELCQNVLTLIKEKAANKGVKLSLELDPHIKTFVADPLRLKQMLLNLLF
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCHHHHHHHHHHHHH
NALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLALLFQPYFQIPNSSVAQHEGTG
HHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCCCHHCCCCC
LGLVVTRKLAEIHNGSVEVESQVDHGSRFTIILPLQQNGQVLVGEDMEDEETTSPASLTP
EEHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSSKDILLVEDDLPNGELMQTHLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDG
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCEEEEEEEECCCC
DGLDLVKQLREKSQYQQIPIIAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHH
SQL
HCC
>Mature Secondary Structure
MQQYSSLPEHNSSIDTTPTLLAKSQQLCAELWLERSLNQLQTRLLNCLESAFNSVPTRTT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EADIFQTVVNELDIALNNSNVGFPLCAVGIALLQPQAAVGKVYYISRPLSLGCQPPLLEE
HHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCHHHCEEEEEECCCCCCCCCHHHHH
ISKDGKKLRLQLQEAIKITDLQKLEKQQPPQAWQLRDDADGVIGWLLLATDNSKPHENAF
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCC
TAPHPQLNTQLMERSAEQCVKALAHLKKIQSLQQKSQNLGISNQELERTNQLKNQFLANT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
SHEIRTPLSSIIGFTHLLLAQGYDPTRERHHEYLNIIQSSGKHLLALINDILDLSKIEAN
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
QLEVQWEKVNVPELCQNVLTLIKEKAANKGVKLSLELDPHIKTFVADPLRLKQMLLNLLF
CEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCHHHHHHHHHHHHH
NALKFTNQGTVGLKVTQRESFIHFTVWDTGSGISPENLALLFQPYFQIPNSSVAQHEGTG
HHHHHCCCCCEEEEEECCCCEEEEEEEECCCCCCHHHHEEEEEHHHCCCCCCCHHCCCCC
LGLVVTRKLAEIHNGSVEVESQVDHGSRFTIILPLQQNGQVLVGEDMEDEETTSPASLTP
EEHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCCCC
NSSKDILLVEDDLPNGELMQTHLSKLGYNVTWVKNAHEMWAKLDQQQAAVILMDIRLPDG
CCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCEEEEEEEECCCC
DGLDLVKQLREKSQYQQIPIIAQTAMAMKGDRSICLSAGVNDYISKPIDLNLLASLVAKY
CCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCHHHHCCCCCHHHHHHHHHHH
SQL
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]