Click here to switch to the map view.

The map label for this gene is thyX [H]

Identifier: 75909127

GI number: 75909127

Start: 3623508

End: 3624230

Strand: Direct

Name: thyX [H]

Synonym: Ava_2917

Alternate gene names: 75909127

Gene position: 3623508-3624230 (Clockwise)

Preceding gene: 75909124

Following gene: 75909128

Centisome position: 56.92

GC content: 44.67

Gene sequence:

>723_bases
ATGGATCGATTCCGAGTAGAAGTTATAGCTAAAACACCAAACCCCCAGCAGGTGATTTACGCCGCAATGCACCAAGACTA
TACTGATGGGTTCGTGTTTGACGAGCGCGACTCCTGGCCCTCGGAGTCGGAATGTGGCGACATTATTATTAAGCGCCTGT
TAGCTGGGGAAAGAGGACACTATGGCCCGTTAGAGCATCCCCAGATTGTTTTCAACTGCGGCTATTTTCCCCACAGTGTT
ATGCAGCAGGCGCGTACACATAGGGTTTCAGTATCATTTGATGTACAATCTTTTAGGTATACGGGTAACCAGTTTATTGA
TGTAGTCGAAGGTAGAAAAGACATTGAAGATGTTTTTTACCTGCGTCCTGTTGGTTATTACACAGATAGACAGGGCAAAA
AATATTACTATTCTCCAGAACAAAGAGCCGCAGATTTGCAGTGGTGTTTAGAAGCAGCTAAACGTTACAAAGCTGATTTT
GAAGGGGGAATGTCTGAAGAACACGCACGAGGTAAAGTACCCTTTGATTATCGCCAGCATTTCGTCGTCAGCTTTAACCT
GCGCTCATTTTTGCACTTTTGTGACTTACGCAATAAGAAAGATGCACAACTGGAAATTCAAAAGTTGTGTGAATTGATGT
GGCCTCATTTTGCAGAGTGGTCTCCGGCGATCGCTCAATGGTATGAAAAATCCCGTCTGGGTAGAGCCAGGCTATCACCA
TAA

Upstream 100 bases:

>100_bases
ATCTGAAGATATATCATGGTGAATCGAGTTCACAACCACGTCTAAAGAACACCTTTAGCTTTTAGACAATTTCAGTTACA
CATAAAACTCCCAGAAGCCA

Downstream 100 bases:

>100_bases
TTCAACCGCTTTCCACTTATAGGTGTAATTTTATCGACCCTCGGCTAGCCATCGAGGGTTTTTTTAGGTGTAAGGGTGTA
AGGGTTTCAAATATTTATAC

Product: thymidylate synthase complementing protein ThyX

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGRKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKSRLGRARLSP

Sequences:

>Translated_240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGRKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKSRLGRARLSP
>Mature_240_residues
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGHYGPLEHPQIVFNCGYFPHSV
MQQARTHRVSVSFDVQSFRYTGNQFIDVVEGRKDIEDVFYLRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADF
EGGMSEEHARGKVPFDYRQHFVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKSRLGRARLSP

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 28313; Mature: 28313

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGH
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
YGPLEHPQIVFNCGYFPHSVMQQARTHRVSVSFDVQSFRYTGNQFIDVVEGRKDIEDVFY
CCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEHHHHHHCCHHHHHHHCCHHHHHHHHH
LRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADFEGGMSEEHARGKVPFDYRQH
HCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCE
FVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKSRLGRARLSP
EEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDRFRVEVIAKTPNPQQVIYAAMHQDYTDGFVFDERDSWPSESECGDIIIKRLLAGERGH
CCCEEEEEEEECCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCC
YGPLEHPQIVFNCGYFPHSVMQQARTHRVSVSFDVQSFRYTGNQFIDVVEGRKDIEDVFY
CCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEHHHHHHCCHHHHHHHCCHHHHHHHHH
LRPVGYYTDRQGKKYYYSPEQRAADLQWCLEAAKRYKADFEGGMSEEHARGKVPFDYRQH
HCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCE
FVVSFNLRSFLHFCDLRNKKDAQLEIQKLCELMWPHFAEWSPAIAQWYEKSRLGRARLSP
EEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA