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The map label for this gene is engA

Identifier: 75909106

GI number: 75909106

Start: 3599776

End: 3601137

Strand: Direct

Name: engA

Synonym: Ava_2896

Alternate gene names: 75909106

Gene position: 3599776-3601137 (Clockwise)

Preceding gene: 75909105

Following gene: 75909107

Centisome position: 56.55

GC content: 47.21

Gene sequence:

>1362_bases
ATGGGACTGCCAATTGTTGCAATTATCGGTCGCCCAAATGTGGGCAAATCAACCCTGGTTAATCGTCTCGCCGGGGAACA
AACGGCGATTGTCCACGATGAACCGGGTGTGACACGCGATCGCACTTACTTACCAGCCTACTGGAGCGATCGGGAATTTC
AAGTAGTAGATACAGGCGGCTTAGTCTTTAACGATGACACAGAATTCTTGCCCCTGATCCGCCAACAAGCATTAGCTGCC
CTCCACGAAGCCAGCGCGGCTATTTTCGTTGTTAATGGTCAAACAGGCCCCAATTCGGCAGATGAAGAAATTGCCGAGTG
GTTACGCCAACAACCAGTACCAGTCTTCTTGGCAGTTAACAAATGCGAATCCCCAGACCAGGGATCGATTCAAGCCTCCG
AATTTTGGGAACTGGGACTAGGAGAACCTTACCCAATCTCTGCGATTCATGGCAACGGTACAGGCGAATTACTCGACGAA
CTCATTAAACACCTTCCTCCGACTACAGAATTAGAAGAAAATAACGAAATCAAAATTGCCATTATTGGCAGACCAAATGT
TGGCAAATCAAGTTTATTAAACGCTTTTGCTGGGGAGGAACGGGTAATAGTCAGCCCCATTTCTGGGACAACCCGTGATG
CGATCGATACTTTTATCGAACGAAATGGGCAGAACTACCGTCTCATCGATACAGCCGGGATTCGCAAAAAGAAAAGCATT
GACTATGGTACGGAATTCTTTAGTATTAACCGTGCTTTTAAAGCCATTCGCCGCGCCGATGTAGTTTTGTTGGTCATAGA
TGCCTTGGATGGTGTCACCGAACAAGACCAAAAGCTAGCAGGCAGAATTCTCGATGAAGGTAAGGCTTGTGTCGTCGTCG
TCAATAAATGGGATGCCGTTGAAAAAGACTCCTATACTATCTACGACTATGAGAAAAATCTGGAAGCACGGCTACATTTT
ACAGAATGGGCTGACACTATCTACGTCAGTGCGGTCACAGGACAACGGGTAGAAAAGATTTTAGAGTTGGTGACTAAAGC
CAATGAAGAACACAAACGCCGCGTTAGCACATCAGTGATTAACGAAGTTCTGGAAGACGCAGTTAGTTGGCACTCTCCCC
CAACCTCTCGCGGCGGTCGCCAAGGGAGAATTTACTACGGTACACAAGTCAGCACTCAACCACCCACCATTGCCTTATTT
GTCAACGAGGCTAAACGCTTTAACGACAACTACCGTCGTTACATTGAAAGGCAATTCCGCCAACAATTAGGCTTTAAAGG
GACTCCCATTCGCTTACTGTGGCGCAGTAAAAAAGTTAGAGATGTGGAAAGCGGTAGCGCCAATCGGGCAACTCGCGTTT
AA

Upstream 100 bases:

>100_bases
CAACAAAAAATCTAGGTGCGTAATTCCTAGCTAAATCAAAACTTAAAGTAGCTAAAATGTAGAGATGTGATATAGTATCT
CTCTTACTTACCCTTGGTTT

Downstream 100 bases:

>100_bases
GATTTGTCAATGGTCATTAGTCATAAGTCATTGGTCATTAGTCCTTAGTGTTTAGCTATGAACTGTTGACTATTGACTAT
GAACTATTGATTATGAACTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAA
LHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDE
LIKHLPPTTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKKKSI
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHF
TEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVSWHSPPTSRGGRQGRIYYGTQVSTQPPTIALF
VNEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV

Sequences:

>Translated_453_residues
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAA
LHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDE
LIKHLPPTTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKKKSI
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHF
TEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVSWHSPPTSRGGRQGRIYYGTQVSTQPPTIALF
VNEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
>Mature_452_residues
GLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGGLVFNDDTEFLPLIRQQALAAL
HEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVNKCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDEL
IKHLPPTTELEENNEIKIAIIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKKKSID
YGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAVEKDSYTIYDYEKNLEARLHFT
EWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVINEVLEDAVSWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFV
NEAKRFNDNYRRYIERQFRQQLGFKGTPIRLLWRSKKVRDVESGSANRATRV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=40.343347639485, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=47.2527472527472, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788919, Length=171, Percent_Identity=32.1637426900585, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=47.2527472527472, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323665, Length=135, Percent_Identity=39.2592592592593, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_ANAVT (Q3M929)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_323402.1
- ProteinModelPortal:   Q3M929
- SMR:   Q3M929
- STRING:   Q3M929
- GeneID:   3681401
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_2896
- NMPDR:   fig|240292.3.peg.1564
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q3M929
- ProtClustDB:   PRK00093
- BioCyc:   AVAR240292:AVA_2896-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50664; Mature: 50533

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCEECCCEEEEEECCC
LVFNDDTEFLPLIRQQALAALHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVN
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEE
KCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDELIKHLPPTTELEENNEIKIA
CCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
IIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKKKSI
EEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAV
CCCHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
EKDSYTIYDYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVI
CCCCEEEEEECCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
NEVLEDAVSWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFVNEAKRFNDNYRRYIERQFR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCHHHCCHHHHHHHHHHHH
QQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLPIVAIIGRPNVGKSTLVNRLAGEQTAIVHDEPGVTRDRTYLPAYWSDREFQVVDTGG
CCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEECCCEECCCEEEEEECCC
LVFNDDTEFLPLIRQQALAALHEASAAIFVVNGQTGPNSADEEIAEWLRQQPVPVFLAVN
EEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEEE
KCESPDQGSIQASEFWELGLGEPYPISAIHGNGTGELLDELIKHLPPTTELEENNEIKIA
CCCCCCCCCEEHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEE
IIGRPNVGKSSLLNAFAGEERVIVSPISGTTRDAIDTFIERNGQNYRLIDTAGIRKKKSI
EEECCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
DYGTEFFSINRAFKAIRRADVVLLVIDALDGVTEQDQKLAGRILDEGKACVVVVNKWDAV
CCCHHHHHHHHHHHHHHHCCEEEEEEEHHCCCCHHHHHHHHHHHCCCCEEEEEEECCCCC
EKDSYTIYDYEKNLEARLHFTEWADTIYVSAVTGQRVEKILELVTKANEEHKRRVSTSVI
CCCCEEEEEECCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
NEVLEDAVSWHSPPTSRGGRQGRIYYGTQVSTQPPTIALFVNEAKRFNDNYRRYIERQFR
HHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCHHHCCHHHHHHHHHHHH
QQLGFKGTPIRLLWRSKKVRDVESGSANRATRV
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA