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The map label for this gene is murG

Identifier: 75909100

GI number: 75909100

Start: 3589823

End: 3590896

Strand: Direct

Name: murG

Synonym: Ava_2890

Alternate gene names: 75909100

Gene position: 3589823-3590896 (Clockwise)

Preceding gene: 75909087

Following gene: 75909103

Centisome position: 56.39

GC content: 46.65

Gene sequence:

>1074_bases
ATGGTAAACGCACCGATAAAATTACTAATAGCTGCCAGTGGGACTGGTGGACACTTGTTTCCGGCGATCGCACTGGCAGA
AAAATTACCAGACTATGAGATTGAATGGCTTGGTGTCCCCAATCGCCTAGAGACTCAGCTAGTCCCTAAACAATATCCTT
TGAATACTATTGCAGTCGAAGGGTTTCAGCAAGGCTTGGGACTTTCATCTTTAGTAATATTAGGTAAACTGATCGGTTCG
ATTCTGAAAGTCCGCCGACTGTTGAAACAAGGTAATTTTCAAGGAGTTGTCACCACAGGGGGATATATCGCCGGGCCAGC
CGTGATTGCAGCGCGTTCTCTGGGTTTACCTGTAATTTTTCATGAATCGAATGCTTTACCCGGCAAAGTTACCCGCTTTT
TTGGCCCTTGGTGTAGTGTAGTCGCCTTAGGATTTGATGTGGCTGCGAAGTATTTACCCCGTGCTACGAATGTTTGTGTG
GGGACTCCAGTGCGATCGCAATTCTTAAATCTAAGTAATAATTCGCAACTAGATTTAGCCATTCCTGGCGGTGTCCCTGT
AATTGTGGTGTTTGGGGGTAGCCAAGGGGCGGTGGCGGTGAATCAGTTAGTGCGTCAAGCGGCTCCAGCTTGGTTTGAGG
CTGGGGCTTATGTGGTACATTTAACAGGCGATCGCGATCCTGATGTTGATAGTCTCAAGCATCCCCAATATATAGAATTA
CCCTTCTACGACAATATGGCGGCTTTGCTGCAACGGGCTAGTTTAGCAATTAGCCGTTCTGGTGCTGGTAGCTTAACAGA
ATTGGCTGTGTGTGGCACACCAGCAATTTTGATTCCCTACCCCTTTGCGGCGGAAGACCATCAATCTTACAACGCTGAGG
TATTTACCAAAGCTGGGGCGGCGTTAAGCTTTAAGCAATCTGCTTTAACAGCAGAGTTATTGCAAAATCAAGTTTTAAAT
TTATTACAGTCCCCCCCAGAGTTAGCCAAAATGGGGGAAAATGCCAAGGCTATCGCTGTTCCTGATAGTGCTGATAAGTT
GGCAGTTCTAGTACGGGAAGTTGTGGAGAGATGA

Upstream 100 bases:

>100_bases
AAATCATCTTTGTCATAGCGAAGAGTTTACTGATGGGAGTGGAGAAGGACAGGAAATTGTTTTATCTTAGTTAAGCTAGG
CGCTAAACGGTAGACTTTGC

Downstream 100 bases:

>100_bases
GTCAATTCAAAATAAAGAGTCAATAGTCAACAGTCTCACCTGTTGTTAGTATTGGGGCATAAGGTGCGATCGCTTTTTGT
CACATCCAGATTAGTTTTTA

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVEGFQQGLGLSSLVILGKLIGS
ILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVAAKYLPRATNVCV
GTPVRSQFLNLSNNSQLDLAIPGGVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIEL
PFYDNMAALLQRASLAISRSGAGSLTELAVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALSFKQSALTAELLQNQVLN
LLQSPPELAKMGENAKAIAVPDSADKLAVLVREVVER

Sequences:

>Translated_357_residues
MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVEGFQQGLGLSSLVILGKLIGS
ILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVAAKYLPRATNVCV
GTPVRSQFLNLSNNSQLDLAIPGGVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIEL
PFYDNMAALLQRASLAISRSGAGSLTELAVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALSFKQSALTAELLQNQVLN
LLQSPPELAKMGENAKAIAVPDSADKLAVLVREVVER
>Mature_357_residues
MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVEGFQQGLGLSSLVILGKLIGS
ILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIFHESNALPGKVTRFFGPWCSVVALGFDVAAKYLPRATNVCV
GTPVRSQFLNLSNNSQLDLAIPGGVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIEL
PFYDNMAALLQRASLAISRSGAGSLTELAVCGTPAILIPYPFAAEDHQSYNAEVFTKAGAALSFKQSALTAELLQNQVLN
LLQSPPELAKMGENAKAIAVPDSADKLAVLVREVVER

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=33.2402234636872, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_ANAVT (Q3M935)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_323396.1
- ProteinModelPortal:   Q3M935
- SMR:   Q3M935
- STRING:   Q3M935
- GeneID:   3681454
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_2890
- NMPDR:   fig|240292.3.peg.1559
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q3M935
- ProtClustDB:   CLSK2396759
- BioCyc:   AVAR240292:AVA_2890-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 37822; Mature: 37822

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVE
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCHHHHHH
GFQQGLGLSSLVILGKLIGSILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECCHHHHHHHHCCCEEEE
HESNALPGKVTRFFGPWCSVVALGFDVAAKYLPRATNVCVGTPVRSQFLNLSNNSQLDLA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCCCEEEEE
IPGGVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIEL
ECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHCCCCCEEEC
PFYDNMAALLQRASLAISRSGAGSLTELAVCGTPAILIPYPFAAEDHQSYNAEVFTKAGA
CCCCCHHHHHHHHHHHEECCCCCCHHEEEECCCCEEEEECCCCCCCCCCCCCEEEECCCC
ALSFKQSALTAELLQNQVLNLLQSPPELAKMGENAKAIAVPDSADKLAVLVREVVER
EEEHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNAPIKLLIAASGTGGHLFPAIALAEKLPDYEIEWLGVPNRLETQLVPKQYPLNTIAVE
CCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCHHHHHH
GFQQGLGLSSLVILGKLIGSILKVRRLLKQGNFQGVVTTGGYIAGPAVIAARSLGLPVIF
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEECCHHHHHHHHCCCEEEE
HESNALPGKVTRFFGPWCSVVALGFDVAAKYLPRATNVCVGTPVRSQFLNLSNNSQLDLA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHCCCCCCCEEEEE
IPGGVPVIVVFGGSQGAVAVNQLVRQAAPAWFEAGAYVVHLTGDRDPDVDSLKHPQYIEL
ECCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHCCCCCEEEC
PFYDNMAALLQRASLAISRSGAGSLTELAVCGTPAILIPYPFAAEDHQSYNAEVFTKAGA
CCCCCHHHHHHHHHHHEECCCCCCHHEEEECCCCEEEEECCCCCCCCCCCCCEEEECCCC
ALSFKQSALTAELLQNQVLNLLQSPPELAKMGENAKAIAVPDSADKLAVLVREVVER
EEEHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA