Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 75909014

GI number: 75909014

Start: 3456036

End: 3456953

Strand: Direct

Name: nahR [H]

Synonym: Ava_2802

Alternate gene names: 75909014

Gene position: 3456036-3456953 (Clockwise)

Preceding gene: 75909010

Following gene: 75909015

Centisome position: 54.29

GC content: 41.83

Gene sequence:

>918_bases
ATGAAATTAATAGATTTATCCTCTATTGACCTCAACCTACTAGTTACGTTTGAGGTGCTTTTTGAAGAGCGAAGTGTCAC
AGTAGCCGCCCAGCGCTTGTATTTAGGACAACCAGCCATGAGTGCGGCTCTTGCAAGGCTACGCATACTATTTCAGGATG
AATTATTTATCCGTATTGGTCGGGAAATGCAACCGACAGCAAAAGCTCTAGAAATTGCTCCAGGTATATCAGTTGCGCTT
CAGCAGATTCGACAGACATTAGAATCTAGCCAAACCTTTGACCCAAAAACTTCTAAACATACCTTTGCCATTGGTAGTTC
GGACTACACCAGCTATGTTGTTCTGCCCAAGTTGTTGGAAGTTTGTCGCCAGGTTGCACCAAGCATTGATTTTCGACTAA
TTGGTTTTGAGAAAGATAGTGTAGGAGACCTGTTAGAACAACGAGAAATTCATGTTGCGTTGGGTTTGTTTCAAAATCCA
CCCCGACAAACGAGACAAATGCCATTATTTGAAGAACACTTTGTTGGTCTTTGTCGCCGTGGACATCCTGTTGTCACTCA
GGAGAATATGACACCGGAGACCTTTGCTTGTCTCCCTCAAGCTCTTTTTACTCTCCGAAGAGATGATATTGGTGAAATTG
ACAAGGTGCTTGCTCAATACAATCTTCAGCGTCGAGTAGTATTGACTACCCCCCACTTGCTCATCTTGCCAACTGTCATT
TCATCTAGTGACTTAGTGACTGTCATTCCTTCACGACTGGTAACACCATTTGCTTACAAAGATACACTAGAAATTTTTGA
ACTTCCTGTAAAAACTGAACCTTGGATGATTTCTATGTTGTGGAGTAAACTTACAGATCAAGATCAAGCGAGTATTTGGT
TACGGCAGATGCTCAAAAGTGTTTGTGAAGGAATTTAA

Upstream 100 bases:

>100_bases
CTTTTGTTCCGTCATTTTTGTGACCTAAAGAATGCTTTTAGGTTTACTGTACTGAGATGTTATAAATTAAGCAAATTGAT
TGCAGCGATATATTTTATTA

Downstream 100 bases:

>100_bases
GCTAAATCGCCGCATAATAAGCTTCATCTACTTTTAATGTTGTCTCTGTGATGAATTTGGCATCATCGGAAATCAGCAAA
GGGCGTTGCTGATTAGTGGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKLIDLSSIDLNLLVTFEVLFEERSVTVAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEIAPGISVAL
QQIRQTLESSQTFDPKTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNP
PRQTRQMPLFEEHFVGLCRRGHPVVTQENMTPETFACLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
SSSDLVTVIPSRLVTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI

Sequences:

>Translated_305_residues
MKLIDLSSIDLNLLVTFEVLFEERSVTVAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEIAPGISVAL
QQIRQTLESSQTFDPKTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNP
PRQTRQMPLFEEHFVGLCRRGHPVVTQENMTPETFACLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
SSSDLVTVIPSRLVTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI
>Mature_305_residues
MKLIDLSSIDLNLLVTFEVLFEERSVTVAAQRLYLGQPAMSAALARLRILFQDELFIRIGREMQPTAKALEIAPGISVAL
QQIRQTLESSQTFDPKTSKHTFAIGSSDYTSYVVLPKLLEVCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNP
PRQTRQMPLFEEHFVGLCRRGHPVVTQENMTPETFACLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
SSSDLVTVIPSRLVTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKSVCEGI

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=26.2295081967213, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081766, Length=284, Percent_Identity=25.3521126760563, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786820, Length=271, Percent_Identity=26.1992619926199, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=22.742474916388, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34626; Mature: 34626

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIDLSSIDLNLLVTFEVLFEERSVTVAAQRLYLGQPAMSAALARLRILFQDELFIRIG
CCEEECCCCCEEHEEEEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
REMQPTAKALEIAPGISVALQQIRQTLESSQTFDPKTSKHTFAIGSSDYTSYVVLPKLLE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNPPRQTRQMPLFEEHFVGLCRR
HHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCCHHHHHHHHHHC
GHPVVTQENMTPETFACLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
CCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
SSSDLVTVIPSRLVTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKS
CCCCEEEECHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VCEGI
HHCCC
>Mature Secondary Structure
MKLIDLSSIDLNLLVTFEVLFEERSVTVAAQRLYLGQPAMSAALARLRILFQDELFIRIG
CCEEECCCCCEEHEEEEEHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
REMQPTAKALEIAPGISVALQQIRQTLESSQTFDPKTSKHTFAIGSSDYTSYVVLPKLLE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHH
VCRQVAPSIDFRLIGFEKDSVGDLLEQREIHVALGLFQNPPRQTRQMPLFEEHFVGLCRR
HHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHEEECCCCCCHHHHCCCCHHHHHHHHHHC
GHPVVTQENMTPETFACLPQALFTLRRDDIGEIDKVLAQYNLQRRVVLTTPHLLILPTVI
CCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEHHH
SSSDLVTVIPSRLVTPFAYKDTLEIFELPVKTEPWMISMLWSKLTDQDQASIWLRQMLKS
CCCCEEEECHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
VCEGI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]