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The map label for this gene is kshA [H]

Identifier: 75908714

GI number: 75908714

Start: 3094630

End: 3095709

Strand: Direct

Name: kshA [H]

Synonym: Ava_2500

Alternate gene names: 75908714

Gene position: 3094630-3095709 (Clockwise)

Preceding gene: 75908711

Following gene: 75908715

Centisome position: 48.61

GC content: 36.39

Gene sequence:

>1080_bases
ATGGATGCAAACTCTCCGCATATCAAGGCTACTCATAAACCGAAAATTTTTAATAATTCAGAACGTTTTATTGAGGGATG
GTATTGGGTAATACCATCTGATAATTTAGGAATAAATGAAGTAAAATCTATCACTCTCTTAGGTAGGAAACTAGTAATTT
ATCGCGGACAAGATTACCAAGTAACTATTTGTGATGCCTATTGTCCACATATGGGCGCTCACTTGGGAGAAGGTACTGTT
GAAGGTAATGAATTACGCTGTGCTTTCCATCACTGGAAATTTAATGCTGATGGAATATGTGTGGAGATTCCGTGTTTAGA
TGAACCTCTGTCCCTCAAGTTAAAAACTTGGCCGACGGTGGAGAAGTACGGAATAATATGGATTTGGACTGGAGAAATAC
CACGAGAATCTGTACCATTCGTTCCAGAGTTAGAGTTTCAGGATTACGAGGCTGTTCTCGGTTCTAGTTTTGTGATAAAT
TGCCATCCTCATCTAATTATGTTGAATGCTATTGATACTCAATATTTTCAAGGAGTCCAGGTTTTAGATATTGGCTTTGA
AAAACAGGAATTAAATCAAAATGCCATTATTTTTAGTAAATATAAACGACAATATCATGATTTGCCGTTTAAAAAAGTCT
TTCGTCCTTTATACAAAAATCCTATTTATAGTATTTGCTATTGGTATGGTAGTACAGTCACTTTAACCGTAGGAACAGAC
TTACGCCGTTGCTATCTGATGTTAGCTTTGCGGTTAATTGCAGGGGAACAGGTAGAAGTACAAACTATATTTTTTACTAA
GCAACGTAAAGGTCTTTTGGGTTGGTTATTTAACCGTTTGATGTTATGGCTGAGTAATTCTTTGGTGCAGGAATTAATCA
GGGATGAGAGAAACATTTTACAGAATATGCAGTTTAATTTAAAAAATCCCATCAAAGTAGATCAATCGATTGTGCAATTA
ATCAATCATGTGGAAATGCAAAAACCTTTGATGTGGAAGACTTGGCTGTTAGCGCGATCGCCTGAGACAGAGGTAAAGGA
AACTCAGACTAAATGGCGAGATGAATTGACTAACGATTAA

Upstream 100 bases:

>100_bases
TCATGAATTTGGTTATTGAAGCCAGTACTCAAAATAACTGTTTTTGTAATATATCCATGCTATTCCTAAGGTAAATGCTT
CACTGTCAGTGAAACCTCAA

Downstream 100 bases:

>100_bases
AAAAAGATAAAAAGTAGAAAGTTCTCTATCATGACTTTTTACTTTTTCCAGTCAGGCAATTGCACTCATAAAAAGAAGTG
GCAAAGCCACTTCAGATTTC

Product: Rieske (2Fe-2S) protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDANSPHIKATHKPKIFNNSERFIEGWYWVIPSDNLGINEVKSITLLGRKLVIYRGQDYQVTICDAYCPHMGAHLGEGTV
EGNELRCAFHHWKFNADGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVIN
CHPHLIMLNAIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQYHDLPFKKVFRPLYKNPIYSICYWYGSTVTLTVGTD
LRRCYLMLALRLIAGEQVEVQTIFFTKQRKGLLGWLFNRLMLWLSNSLVQELIRDERNILQNMQFNLKNPIKVDQSIVQL
INHVEMQKPLMWKTWLLARSPETEVKETQTKWRDELTND

Sequences:

>Translated_359_residues
MDANSPHIKATHKPKIFNNSERFIEGWYWVIPSDNLGINEVKSITLLGRKLVIYRGQDYQVTICDAYCPHMGAHLGEGTV
EGNELRCAFHHWKFNADGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVIN
CHPHLIMLNAIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQYHDLPFKKVFRPLYKNPIYSICYWYGSTVTLTVGTD
LRRCYLMLALRLIAGEQVEVQTIFFTKQRKGLLGWLFNRLMLWLSNSLVQELIRDERNILQNMQFNLKNPIKVDQSIVQL
INHVEMQKPLMWKTWLLARSPETEVKETQTKWRDELTND
>Mature_359_residues
MDANSPHIKATHKPKIFNNSERFIEGWYWVIPSDNLGINEVKSITLLGRKLVIYRGQDYQVTICDAYCPHMGAHLGEGTV
EGNELRCAFHHWKFNADGICVEIPCLDEPLSLKLKTWPTVEKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVIN
CHPHLIMLNAIDTQYFQGVQVLDIGFEKQELNQNAIIFSKYKRQYHDLPFKKVFRPLYKNPIYSICYWYGSTVTLTVGTD
LRRCYLMLALRLIAGEQVEVQTIFFTKQRKGLLGWLFNRLMLWLSNSLVQELIRDERNILQNMQFNLKNPIKVDQSIVQL
INHVEMQKPLMWKTWLLARSPETEVKETQTKWRDELTND

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=163, Percent_Identity=34.3558282208589, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161085896, Length=163, Percent_Identity=39.2638036809816, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 42046; Mature: 42046

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDANSPHIKATHKPKIFNNSERFIEGWYWVIPSDNLGINEVKSITLLGRKLVIYRGQDYQ
CCCCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHEEEECCEEEEEECCCCE
VTICDAYCPHMGAHLGEGTVEGNELRCAFHHWKFNADGICVEIPCLDEPLSLKLKTWPTV
EEEECCCCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCEEEECCCCH
EKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVINCHPHLIMLNAIDTQYFQGVQ
HHCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCEEEEEECCHHHHCCEE
VLDIGFEKQELNQNAIIFSKYKRQYHDLPFKKVFRPLYKNPIYSICYWYGSTVTLTVGTD
EEEECCCHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCHHEEEEEECCEEEEEECCH
LRRCYLMLALRLIAGEQVEVQTIFFTKQRKGLLGWLFNRLMLWLSNSLVQELIRDERNIL
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNMQFNLKNPIKVDQSIVQLINHVEMQKPLMWKTWLLARSPETEVKETQTKWRDELTND
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEHEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDANSPHIKATHKPKIFNNSERFIEGWYWVIPSDNLGINEVKSITLLGRKLVIYRGQDYQ
CCCCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHEEEECCEEEEEECCCCE
VTICDAYCPHMGAHLGEGTVEGNELRCAFHHWKFNADGICVEIPCLDEPLSLKLKTWPTV
EEEECCCCCHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCCEEEECCCCH
EKYGIIWIWTGEIPRESVPFVPELEFQDYEAVLGSSFVINCHPHLIMLNAIDTQYFQGVQ
HHCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCEEEEECCCCEEEEEECCHHHHCCEE
VLDIGFEKQELNQNAIIFSKYKRQYHDLPFKKVFRPLYKNPIYSICYWYGSTVTLTVGTD
EEEECCCHHHCCCCCEEEHHHHHHHHCCCHHHHHHHHHCCCHHEEEEEECCEEEEEECCH
LRRCYLMLALRLIAGEQVEVQTIFFTKQRKGLLGWLFNRLMLWLSNSLVQELIRDERNIL
HHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNMQFNLKNPIKVDQSIVQLINHVEMQKPLMWKTWLLARSPETEVKETQTKWRDELTND
HHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEHEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA