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The map label for this gene is xylR [H]

Identifier: 75908482

GI number: 75908482

Start: 2820421

End: 2821356

Strand: Direct

Name: xylR [H]

Synonym: Ava_2265

Alternate gene names: 75908482

Gene position: 2820421-2821356 (Clockwise)

Preceding gene: 75908481

Following gene: 75908485

Centisome position: 44.31

GC content: 46.37

Gene sequence:

>936_bases
ATGATTTCTGCTGTGGTGGTTTGGTGTGAGGAATTGAACGTGGGGAATTCTCAAGTAATTGGCATTGACTTGGGGGGAAC
AGCAATTAAACTGGGGCGATTTAGCGAAGATGGGACTTGTTCACAATCTTTGACTGTAGAGACTCCCCAACCAGCAACCC
CAGAAGCGGTTTTTCTGGTAATGGTGGATGCGATCGCGCAAATTGACCCAGATAATGAAACTATAGCTATTGGTGTGGGT
ACTCCTGGCCCGGCTGATGCTCAAGGACGCATTGCCCAAATTGCGATTAACTTACCCCAATGGGAAAATGTGCCTTTAGC
TGATTGGTTAGAAACGAAAACTAACAAGCCGACAGTAATTGAAAATGATGCCAACTGTGCAGGAATCGCTGAGGCGTGGT
TAGGAGCCGGTCGCCACTACCAAAACTTTATCATGCTAACTTTGGGGACTGGCGTTGGTGGCGCAATTTTTTTAGACGGT
AAATTATTTGTTGGACATCGCGGCGCGGCTGGGGAATTGGGATTAATTACACTCCAACCAGATGGCCCCATGTGTAAAAG
TGGCAACCCTGGTTCTTTAGAACAGTACACTTCCATTAAAGCTATTCGTCGCCTGACTGGTAAAGAACCTGCGGAGTTAG
GTATGCTAGCTCAAGCTGGAGATATAGAAGCCTTACAATTTTGGCAAGAATACGGACAAAATTTAGGTATAGGTTTAACT
AGTTTAATTTATGTTCTCACACCACAGGCGATCGTGCTTGGCGGTGGTGTCAGTGCCAGCCATGAGTTTTTCTTACCAAC
TCTCAAAGCCGAAATCGAACAGCGAGTCATGTCCACATCCCGCGCAGGCTTACAAATCTTGCCAGCAGAGTTGGGTAACT
CAGCCGGTATGGTAGGTGCAGCAAGATTAGCTTGGAAAAAGTTTGGTAATGGGTAA

Upstream 100 bases:

>100_bases
ACTGAGAACTTAGAATTTTTTGGCCCAGAAATCCCAAAAAGCTAATATGCTTTTGTGAAATACCCCAAATGGGTAATTAT
CGTCAGCTCAATCAAAGCTG

Downstream 100 bases:

>100_bases
TTGGTAATGGTTGATTCAAAACTATTGACTATTGACTATGGACTAAGAAAAAGAATGTCCTGTGGTTTTTTGGACGTATT
GCAAAACCTTTTTATAAGAA

Product: ROK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MISAVVVWCEELNVGNSQVIGIDLGGTAIKLGRFSEDGTCSQSLTVETPQPATPEAVFLVMVDAIAQIDPDNETIAIGVG
TPGPADAQGRIAQIAINLPQWENVPLADWLETKTNKPTVIENDANCAGIAEAWLGAGRHYQNFIMLTLGTGVGGAIFLDG
KLFVGHRGAAGELGLITLQPDGPMCKSGNPGSLEQYTSIKAIRRLTGKEPAELGMLAQAGDIEALQFWQEYGQNLGIGLT
SLIYVLTPQAIVLGGGVSASHEFFLPTLKAEIEQRVMSTSRAGLQILPAELGNSAGMVGAARLAWKKFGNG

Sequences:

>Translated_311_residues
MISAVVVWCEELNVGNSQVIGIDLGGTAIKLGRFSEDGTCSQSLTVETPQPATPEAVFLVMVDAIAQIDPDNETIAIGVG
TPGPADAQGRIAQIAINLPQWENVPLADWLETKTNKPTVIENDANCAGIAEAWLGAGRHYQNFIMLTLGTGVGGAIFLDG
KLFVGHRGAAGELGLITLQPDGPMCKSGNPGSLEQYTSIKAIRRLTGKEPAELGMLAQAGDIEALQFWQEYGQNLGIGLT
SLIYVLTPQAIVLGGGVSASHEFFLPTLKAEIEQRVMSTSRAGLQILPAELGNSAGMVGAARLAWKKFGNG
>Mature_311_residues
MISAVVVWCEELNVGNSQVIGIDLGGTAIKLGRFSEDGTCSQSLTVETPQPATPEAVFLVMVDAIAQIDPDNETIAIGVG
TPGPADAQGRIAQIAINLPQWENVPLADWLETKTNKPTVIENDANCAGIAEAWLGAGRHYQNFIMLTLGTGVGGAIFLDG
KLFVGHRGAAGELGLITLQPDGPMCKSGNPGSLEQYTSIKAIRRLTGKEPAELGMLAQAGDIEALQFWQEYGQNLGIGLT
SLIYVLTPQAIVLGGGVSASHEFFLPTLKAEIEQRVMSTSRAGLQILPAELGNSAGMVGAARLAWKKFGNG

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=283, Percent_Identity=28.2685512367491, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI298566325, Length=283, Percent_Identity=28.2685512367491, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI4885285, Length=283, Percent_Identity=28.2685512367491, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI190014632, Length=283, Percent_Identity=28.2685512367491, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1787363, Length=309, Percent_Identity=28.1553398058252, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786891, Length=322, Percent_Identity=26.7080745341615, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790522, Length=296, Percent_Identity=26.6891891891892, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787878, Length=244, Percent_Identity=26.2295081967213, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI87081733, Length=303, Percent_Identity=27.3927392739274, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082230, Length=244, Percent_Identity=28.2786885245902, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 32666; Mature: 32666

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAVVVWCEELNVGNSQVIGIDLGGTAIKLGRFSEDGTCSQSLTVETPQPATPEAVFLV
CCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCCHHHHHH
MVDAIAQIDPDNETIAIGVGTPGPADAQGRIAQIAINLPQWENVPLADWLETKTNKPTVI
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEE
ENDANCAGIAEAWLGAGRHYQNFIMLTLGTGVGGAIFLDGKLFVGHRGAAGELGLITLQP
ECCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCEEEEECCCCCCCEEEEEECC
DGPMCKSGNPGSLEQYTSIKAIRRLTGKEPAELGMLAQAGDIEALQFWQEYGQNLGIGLT
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCEEECCCCHHHHHHHHHHCCCCCCCHH
SLIYVLTPQAIVLGGGVSASHEFFLPTLKAEIEQRVMSTSRAGLQILPAELGNSAGMVGA
HHHHHHCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCHHH
ARLAWKKFGNG
HHHHHHHCCCC
>Mature Secondary Structure
MISAVVVWCEELNVGNSQVIGIDLGGTAIKLGRFSEDGTCSQSLTVETPQPATPEAVFLV
CCCEEEEEEECCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCCCCCHHHHHH
MVDAIAQIDPDNETIAIGVGTPGPADAQGRIAQIAINLPQWENVPLADWLETKTNKPTVI
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCEEE
ENDANCAGIAEAWLGAGRHYQNFIMLTLGTGVGGAIFLDGKLFVGHRGAAGELGLITLQP
ECCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCEEEEECCCCCCCEEEEEECC
DGPMCKSGNPGSLEQYTSIKAIRRLTGKEPAELGMLAQAGDIEALQFWQEYGQNLGIGLT
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCEEECCCCHHHHHHHHHHCCCCCCCHH
SLIYVLTPQAIVLGGGVSASHEFFLPTLKAEIEQRVMSTSRAGLQILPAELGNSAGMVGA
HHHHHHCCCEEEEECCCCCCCEEECHHHHHHHHHHHHHHCCCCEEEEHHHCCCCCCCHHH
ARLAWKKFGNG
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]