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The map label for this gene is dnaX [H]

Identifier: 75908432

GI number: 75908432

Start: 2750635

End: 2752587

Strand: Direct

Name: dnaX [H]

Synonym: Ava_2215

Alternate gene names: 75908432

Gene position: 2750635-2752587 (Clockwise)

Preceding gene: 75908428

Following gene: 75908435

Centisome position: 43.21

GC content: 47.72

Gene sequence:

>1953_bases
ATGTCTTATGTACCCCTGCACCACAAGTATCGCCCAAAGAGTTTTGCTGAACTGGTGGGGCAAGAGGCGATCGCTACCAC
ACTCACAAATGCTATCCGTACGGCTAAAATAGCCCCAGCGTATTTATTTACTGGCCCCAGAGGTACAGGTAAAACCTCCA
GCGCCCGGATTCTGGCTAAATCCCTCAACTGTCTCAACAGTGACAAACCCACAGCCGAACCCTGTGGCGTTTGTGATGTT
TGTCAGGGAATCACCAAAGGCTACTCCCTGGACGTAATCGAAATTGATGCCGCCAGTAACACTGGTGTAGATAACATCCG
CGAATTAATTGAAAAAGCCCAATTCGCCCCCGTGCAGTGTCGGTATAAAGTTTATGTAATCGACGAATGTCATATGCTCA
GTAGTGCGGCATTCAATGCGTTACTGAAAACACTGGAAGAACCACCTAAGCACGTAGTTTTTGTTTTAGCGACAACCGAC
CCCCAACGAGTGTTACCCACGATTATTTCTCGTTGTCAAAGATTTGATTTTCGGCGCATTCAACTAGAGGCGATGGTGAA
GCACTTAAGTGCGATCGCCTCAAAGGAAAATATTAACATTTCCCTAGAAGCTGTCACCTTAGTAGCTCAGTTATCCCAAG
GCGGATTACGAGATGCAGAAAGTTTACTCGACCAATTAGCCTTATTACCTAACGAAGTCACACCAGAGCAAGTATGGGAT
TTAGTCGGTTCAGTCAGCGAACAAGATTTGTTAGTTTTATTGGCAGCGATCGCCCAAGATAACCCAGAATTAGTATTAGA
CTCTACCAGACAAATCTTAGATCGTGGTCGAGAACCCTTAACCATCCTGCAAAACCTAGCCGCCTTCTACCGCGATTTAC
TCATAGCCAAAACCGCACCCAATCGCCATAATTTAGTTGCTTGTACTCAGCAGACATGGAACGCACTAGTTGAATCTGCC
CAATCTTTGCCCATAAGTACCATCTTGCTAGGGCAGAAACATTTACAAGAAGCAGAACTGCAAATTAAACACACCACTCA
ACCACGTTTATGGTTGGAAGTGACATTACTAGGATTATTACCAAGCGCCAGTATTCAACCCGCAGCTATAGCCCTGACAC
CAAGCAACCATCGCCCAGCACCACAGCAAGTTTCCCCAAAAGCACCCCCACAAAACCCATCTCCACAACCCCCTCCTCCA
CCCCCACCAGAAGCCTCCACCCGCCAAGAAACCCCAGACACACCCCCATCCATCCCATCCCCCATCGTGGAGGAAGTTAA
AGCTACATCTTCCCCTGCTCCCCAGTCCTCAATCCCCAGTCCCTCAGAAGATGACTTTGCTCAAATTTGGCAGCAAGTCC
TCAGTAATATTCAACAAATCCCCAGACGCGCCTTACTGGGTCAAATGTGTTACCTCATCGATTTTGCAGGTACTGTGGCT
CGTATTGGTGTCAAAGCTGCGTGGTATGACAAAGTCAAGTCAGACTTACCTATGATTACGAGTGCTTTCCAGCAGACTTT
TAATCGTGAAGTTCAGGTAACCTTAGAAAGGGGTAACCCATCAAACGCTACTACAGTCAGGAAAGTAGCACCAGCCAACG
GTAATGGTAACAGCAACGGTAACGGTCATAACGGTACTTCCAGCGTACAACAGCCACCGTCACCAACCTACAGCAACCAA
AAGCCGACTACACCTCTCCCACAACCTACCGCAACCGCCCCAACTCCAAAAACTACACCAATAGCCCCAAGTACGGGAGG
AGCAAAAACACCGCCCCCAAAAGAGAACCAAGCACCTCTACTGGAGTGGGAAACTGATGAAGTGGCGATCGCTGCCCAAC
GTCTGGCAAAATTCTTTGATGGGCAAATCATCCGATTTACTGACGATGGCGAAGCATTATCAGAAATGGGTACATCTGAG
TGGACGGATGAGTCAGATTTAGACGATGAATAA

Upstream 100 bases:

>100_bases
AGACTCTTTGGGGGCAAAAATTCTCATGATTGGGTGTAAGTAAATTTAAAGCACAACAACTTAGCAAATCAACCCTAGAA
GGTATTGACTTTTTTCACCC

Downstream 100 bases:

>100_bases
TGCAGGGGCAAGAATTAATGTACAGAGGTTGTAGACAATATCTCTAGGACTTACTCATGAAAACGAAAAATCAATGGTTT
AAGGAACTAAAACCATCAGT

Product: AAA ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MSYVPLHHKYRPKSFAELVGQEAIATTLTNAIRTAKIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKPTAEPCGVCDV
CQGITKGYSLDVIEIDAASNTGVDNIRELIEKAQFAPVQCRYKVYVIDECHMLSSAAFNALLKTLEEPPKHVVFVLATTD
PQRVLPTIISRCQRFDFRRIQLEAMVKHLSAIASKENINISLEAVTLVAQLSQGGLRDAESLLDQLALLPNEVTPEQVWD
LVGSVSEQDLLVLLAAIAQDNPELVLDSTRQILDRGREPLTILQNLAAFYRDLLIAKTAPNRHNLVACTQQTWNALVESA
QSLPISTILLGQKHLQEAELQIKHTTQPRLWLEVTLLGLLPSASIQPAAIALTPSNHRPAPQQVSPKAPPQNPSPQPPPP
PPPEASTRQETPDTPPSIPSPIVEEVKATSSPAPQSSIPSPSEDDFAQIWQQVLSNIQQIPRRALLGQMCYLIDFAGTVA
RIGVKAAWYDKVKSDLPMITSAFQQTFNREVQVTLERGNPSNATTVRKVAPANGNGNSNGNGHNGTSSVQQPPSPTYSNQ
KPTTPLPQPTATAPTPKTTPIAPSTGGAKTPPPKENQAPLLEWETDEVAIAAQRLAKFFDGQIIRFTDDGEALSEMGTSE
WTDESDLDDE

Sequences:

>Translated_650_residues
MSYVPLHHKYRPKSFAELVGQEAIATTLTNAIRTAKIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKPTAEPCGVCDV
CQGITKGYSLDVIEIDAASNTGVDNIRELIEKAQFAPVQCRYKVYVIDECHMLSSAAFNALLKTLEEPPKHVVFVLATTD
PQRVLPTIISRCQRFDFRRIQLEAMVKHLSAIASKENINISLEAVTLVAQLSQGGLRDAESLLDQLALLPNEVTPEQVWD
LVGSVSEQDLLVLLAAIAQDNPELVLDSTRQILDRGREPLTILQNLAAFYRDLLIAKTAPNRHNLVACTQQTWNALVESA
QSLPISTILLGQKHLQEAELQIKHTTQPRLWLEVTLLGLLPSASIQPAAIALTPSNHRPAPQQVSPKAPPQNPSPQPPPP
PPPEASTRQETPDTPPSIPSPIVEEVKATSSPAPQSSIPSPSEDDFAQIWQQVLSNIQQIPRRALLGQMCYLIDFAGTVA
RIGVKAAWYDKVKSDLPMITSAFQQTFNREVQVTLERGNPSNATTVRKVAPANGNGNSNGNGHNGTSSVQQPPSPTYSNQ
KPTTPLPQPTATAPTPKTTPIAPSTGGAKTPPPKENQAPLLEWETDEVAIAAQRLAKFFDGQIIRFTDDGEALSEMGTSE
WTDESDLDDE
>Mature_649_residues
SYVPLHHKYRPKSFAELVGQEAIATTLTNAIRTAKIAPAYLFTGPRGTGKTSSARILAKSLNCLNSDKPTAEPCGVCDVC
QGITKGYSLDVIEIDAASNTGVDNIRELIEKAQFAPVQCRYKVYVIDECHMLSSAAFNALLKTLEEPPKHVVFVLATTDP
QRVLPTIISRCQRFDFRRIQLEAMVKHLSAIASKENINISLEAVTLVAQLSQGGLRDAESLLDQLALLPNEVTPEQVWDL
VGSVSEQDLLVLLAAIAQDNPELVLDSTRQILDRGREPLTILQNLAAFYRDLLIAKTAPNRHNLVACTQQTWNALVESAQ
SLPISTILLGQKHLQEAELQIKHTTQPRLWLEVTLLGLLPSASIQPAAIALTPSNHRPAPQQVSPKAPPQNPSPQPPPPP
PPEASTRQETPDTPPSIPSPIVEEVKATSSPAPQSSIPSPSEDDFAQIWQQVLSNIQQIPRRALLGQMCYLIDFAGTVAR
IGVKAAWYDKVKSDLPMITSAFQQTFNREVQVTLERGNPSNATTVRKVAPANGNGNSNGNGHNGTSSVQQPPSPTYSNQK
PTTPLPQPTATAPTPKTTPIAPSTGGAKTPPPKENQAPLLEWETDEVAIAAQRLAKFFDGQIIRFTDDGEALSEMGTSEW
TDESDLDDE

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=294, Percent_Identity=27.2108843537415, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI31881687, Length=294, Percent_Identity=27.2108843537415, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI6677723, Length=244, Percent_Identity=28.2786885245902, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI194306571, Length=239, Percent_Identity=28.4518828451883, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI194306567, Length=239, Percent_Identity=28.4518828451883, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI194306569, Length=156, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI1786676, Length=400, Percent_Identity=39.25, Blast_Score=256, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71986063, Length=253, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554730, Length=227, Percent_Identity=25.9911894273128, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541988, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=267, Percent_Identity=27.7153558052434, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6322528, Length=306, Percent_Identity=23.202614379085, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921076, Length=256, Percent_Identity=26.171875, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647857, Length=245, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 70584; Mature: 70452

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYVPLHHKYRPKSFAELVGQEAIATTLTNAIRTAKIAPAYLFTGPRGTGKTSSARILAK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
SLNCLNSDKPTAEPCGVCDVCQGITKGYSLDVIEIDAASNTGVDNIRELIEKAQFAPVQC
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
RYKVYVIDECHMLSSAAFNALLKTLEEPPKHVVFVLATTDPQRVLPTIISRCQRFDFRRI
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHH
QLEAMVKHLSAIASKENINISLEAVTLVAQLSQGGLRDAESLLDQLALLPNEVTPEQVWD
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LVGSVSEQDLLVLLAAIAQDNPELVLDSTRQILDRGREPLTILQNLAAFYRDLLIAKTAP
HHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
NRHNLVACTQQTWNALVESAQSLPISTILLGQKHLQEAELQIKHTTQPRLWLEVTLLGLL
CCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHEEEEECCCCCEEHHHHHHHHC
PSASIQPAAIALTPSNHRPAPQQVSPKAPPQNPSPQPPPPPPPEASTRQETPDTPPSIPS
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PIVEEVKATSSPAPQSSIPSPSEDDFAQIWQQVLSNIQQIPRRALLGQMCYLIDFAGTVA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGVKAAWYDKVKSDLPMITSAFQQTFNREVQVTLERGNPSNATTVRKVAPANGNGNSNG
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCC
NGHNGTSSVQQPPSPTYSNQKPTTPLPQPTATAPTPKTTPIAPSTGGAKTPPPKENQAPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LEWETDEVAIAAQRLAKFFDGQIIRFTDDGEALSEMGTSEWTDESDLDDE
EEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYVPLHHKYRPKSFAELVGQEAIATTLTNAIRTAKIAPAYLFTGPRGTGKTSSARILAK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHH
SLNCLNSDKPTAEPCGVCDVCQGITKGYSLDVIEIDAASNTGVDNIRELIEKAQFAPVQC
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
RYKVYVIDECHMLSSAAFNALLKTLEEPPKHVVFVLATTDPQRVLPTIISRCQRFDFRRI
EEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHH
QLEAMVKHLSAIASKENINISLEAVTLVAQLSQGGLRDAESLLDQLALLPNEVTPEQVWD
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHH
LVGSVSEQDLLVLLAAIAQDNPELVLDSTRQILDRGREPLTILQNLAAFYRDLLIAKTAP
HHHCCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
NRHNLVACTQQTWNALVESAQSLPISTILLGQKHLQEAELQIKHTTQPRLWLEVTLLGLL
CCCCEEEEHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHEEEEECCCCCEEHHHHHHHHC
PSASIQPAAIALTPSNHRPAPQQVSPKAPPQNPSPQPPPPPPPEASTRQETPDTPPSIPS
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PIVEEVKATSSPAPQSSIPSPSEDDFAQIWQQVLSNIQQIPRRALLGQMCYLIDFAGTVA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGVKAAWYDKVKSDLPMITSAFQQTFNREVQVTLERGNPSNATTVRKVAPANGNGNSNG
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCC
NGHNGTSSVQQPPSPTYSNQKPTTPLPQPTATAPTPKTTPIAPSTGGAKTPPPKENQAPL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LEWETDEVAIAAQRLAKFFDGQIIRFTDDGEALSEMGTSEWTDESDLDDE
EEECCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]