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The map label for this gene is pmbA [C]

Identifier: 75908380

GI number: 75908380

Start: 2673212

End: 2674282

Strand: Direct

Name: pmbA [C]

Synonym: Ava_2161

Alternate gene names: 75908380

Gene position: 2673212-2674282 (Clockwise)

Preceding gene: 75908379

Following gene: 75908381

Centisome position: 41.99

GC content: 46.22

Gene sequence:

>1071_bases
ATGGTAGAACGCGCTCTTGCTTTGAGCGAACTGAACCAATCAGAACCAGTGGAATTGGTCAGCAACTCTAAGCCATCCTA
CCCAGACTTGGGTGAGGCTGTATCTGTAGAAGTTTTAGTTGGTTGGGGCAAAGAAGCGATCGCCATCATCCGCGATAATT
ATCCCGATGTCCTCTGTAATAGTGACTGGGAATGTGATGTGGAAACGACTAGACTTGTCAACACTCAAGGTTTAGATTGC
TACTACAGCGATACTACCCTCAGTTGCTATATGTCCGCCGAATGGGTTCGTGGTGATGATTTTTTAAGTGTATCTGATGG
ACAAACTCAGCGTGATTACTTAGACCCGGAAAAGTTGGCTTATCAAATTTTACAAAGACTGGTTTGGGCTAAAGAAAACG
TCCCACCTCCTAACGGTCGTGTCCCGGTTTTATTTACCTCCAAGGCGGCGGATATGCTTTGGGGTACGGCGCAAGCAGCG
TTGAATGGCAAACGTGTACTAGAAGCAGCTTCCCCTTGGGCAGAACGCGTGGGTAAACAAGTAATCGCTCCTAGCCTTAC
CCTTTACCAAGACCCCCAAGCCGGGCCTTATAGCTGCCCCTTTGATGATGAAGGTACTCCGACCAAATCTTTGGTATTTA
TCGAAAAAGGCATATTACAAAATTATTATTGCGATCGCACCACCGGAAGGCAACTAGGTAATAGCACCACCGGCAATGGT
TTTCGCCCTGGTTTAGGCAGTTATCCCACCCCTGGCTTATTTAACTTTTTGATTAAGCCTGGTTCTAAATCCCTCAAAGA
CCTGATCCAAAACATGGATGATGGCTTGATTGTAGACCAAATGCTCGGTGGTAGTGGTGGTATCTCTGGCGACTTTTCGA
TCAATATCGAATTAGGCTATCGAGTCCAAAAAGGTCAAGTAATCGGTCGCGTCAAAGATACAATGGTCGCAGGCAATGTT
TATACCGCCCTCAAGCAAGTGGAATTAGGCAGTGATGCTGATTGGAACGGTTCTTGTTATACTCCGTCTTTAATAGTCGA
AGGGCTATCGACGACTGGGAGGAATAATTAG

Upstream 100 bases:

>100_bases
ACAGCTAGAAACCAGCCAATCTGAAGGTACGGCACTGCGGCTATAGCGCAAAGGTCGCCCAGGACTCACGGTAGCTTATG
GTTCAGTAGAACCAGGGGCA

Downstream 100 bases:

>100_bases
GAGGCAGGGGAAGCAGGGGAAGCAGGGGAGGCAGGGGAAGCAAGGGGGCAGGGAGCAGGGGGAAGAAAATTGACTATGGA
CAATTTTACAGACGCGATTA

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MVERALALSELNQSEPVELVSNSKPSYPDLGEAVSVEVLVGWGKEAIAIIRDNYPDVLCNSDWECDVETTRLVNTQGLDC
YYSDTTLSCYMSAEWVRGDDFLSVSDGQTQRDYLDPEKLAYQILQRLVWAKENVPPPNGRVPVLFTSKAADMLWGTAQAA
LNGKRVLEAASPWAERVGKQVIAPSLTLYQDPQAGPYSCPFDDEGTPTKSLVFIEKGILQNYYCDRTTGRQLGNSTTGNG
FRPGLGSYPTPGLFNFLIKPGSKSLKDLIQNMDDGLIVDQMLGGSGGISGDFSINIELGYRVQKGQVIGRVKDTMVAGNV
YTALKQVELGSDADWNGSCYTPSLIVEGLSTTGRNN

Sequences:

>Translated_356_residues
MVERALALSELNQSEPVELVSNSKPSYPDLGEAVSVEVLVGWGKEAIAIIRDNYPDVLCNSDWECDVETTRLVNTQGLDC
YYSDTTLSCYMSAEWVRGDDFLSVSDGQTQRDYLDPEKLAYQILQRLVWAKENVPPPNGRVPVLFTSKAADMLWGTAQAA
LNGKRVLEAASPWAERVGKQVIAPSLTLYQDPQAGPYSCPFDDEGTPTKSLVFIEKGILQNYYCDRTTGRQLGNSTTGNG
FRPGLGSYPTPGLFNFLIKPGSKSLKDLIQNMDDGLIVDQMLGGSGGISGDFSINIELGYRVQKGQVIGRVKDTMVAGNV
YTALKQVELGSDADWNGSCYTPSLIVEGLSTTGRNN
>Mature_356_residues
MVERALALSELNQSEPVELVSNSKPSYPDLGEAVSVEVLVGWGKEAIAIIRDNYPDVLCNSDWECDVETTRLVNTQGLDC
YYSDTTLSCYMSAEWVRGDDFLSVSDGQTQRDYLDPEKLAYQILQRLVWAKENVPPPNGRVPVLFTSKAADMLWGTAQAA
LNGKRVLEAASPWAERVGKQVIAPSLTLYQDPQAGPYSCPFDDEGTPTKSLVFIEKGILQNYYCDRTTGRQLGNSTTGNG
FRPGLGSYPTPGLFNFLIKPGSKSLKDLIQNMDDGLIVDQMLGGSGGISGDFSINIELGYRVQKGQVIGRVKDTMVAGNV
YTALKQVELGSDADWNGSCYTPSLIVEGLSTTGRNN

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=307, Percent_Identity=25.7328990228013, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789640, Length=215, Percent_Identity=28.3720930232558, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 38824; Mature: 38824

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERALALSELNQSEPVELVSNSKPSYPDLGEAVSVEVLVGWGKEAIAIIRDNYPDVLCN
CCCHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCEEEC
SDWECDVETTRLVNTQGLDCYYSDTTLSCYMSAEWVRGDDFLSVSDGQTQRDYLDPEKLA
CCCCCCCCCEEEECCCCCEEEECCCEEEEEEEEEEECCCCEEEECCCCCHHHCCCHHHHH
YQILQRLVWAKENVPPPNGRVPVLFTSKAADMLWGTAQAALNGKRVLEAASPWAERVGKQ
HHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
VIAPSLTLYQDPQAGPYSCPFDDEGTPTKSLVFIEKGILQNYYCDRTTGRQLGNSTTGNG
HHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCHHHCCCCCCCCC
FRPGLGSYPTPGLFNFLIKPGSKSLKDLIQNMDDGLIVDQMLGGSGGISGDFSINIELGY
CCCCCCCCCCCHHHHHEECCCCHHHHHHHHCCCCCEEEHHHCCCCCCCCCEEEEEEEEEE
RVQKGQVIGRVKDTMVAGNVYTALKQVELGSDADWNGSCYTPSLIVEGLSTTGRNN
EEECCCEEEHHHHHEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVERALALSELNQSEPVELVSNSKPSYPDLGEAVSVEVLVGWGKEAIAIIRDNYPDVLCN
CCCHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEECCCCEEEEEECCCCCEEEC
SDWECDVETTRLVNTQGLDCYYSDTTLSCYMSAEWVRGDDFLSVSDGQTQRDYLDPEKLA
CCCCCCCCCEEEECCCCCEEEECCCEEEEEEEEEEECCCCEEEECCCCCHHHCCCHHHHH
YQILQRLVWAKENVPPPNGRVPVLFTSKAADMLWGTAQAALNGKRVLEAASPWAERVGKQ
HHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHH
VIAPSLTLYQDPQAGPYSCPFDDEGTPTKSLVFIEKGILQNYYCDRTTGRQLGNSTTGNG
HHCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCHHHCCCCCCCCC
FRPGLGSYPTPGLFNFLIKPGSKSLKDLIQNMDDGLIVDQMLGGSGGISGDFSINIELGY
CCCCCCCCCCCHHHHHEECCCCHHHHHHHHCCCCCEEEHHHCCCCCCCCCEEEEEEEEEE
RVQKGQVIGRVKDTMVAGNVYTALKQVELGSDADWNGSCYTPSLIVEGLSTTGRNN
EEECCCEEEHHHHHEEECHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]