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The map label for this gene is aspC [H]

Identifier: 75908346

GI number: 75908346

Start: 2630038

End: 2631204

Strand: Direct

Name: aspC [H]

Synonym: Ava_2127

Alternate gene names: 75908346

Gene position: 2630038-2631204 (Clockwise)

Preceding gene: 75908345

Following gene: 75908347

Centisome position: 41.32

GC content: 46.27

Gene sequence:

>1167_bases
ATGAAACTGGCAGCAAGAGTAAGTCAGGTAACACCTTCGATAACCTTAGCGATCGCAGCGAAAGCTAAGGCCATGAAGGC
AGAGGGTATAGACGTTTGTAGTTTTAGCGCTGGTGAACCCGACTTTGATACCCCAGCGCATATCAAAGCAGCAGCCGCCA
AGGCTTTGGATGAAGGCAAAACCAAGTATGGTGCAGCAGCTGGAGAACCAAAGTTAAGGGAAGCGATCGCCCACAAGTTG
CAAAAGGATAATCATCTGGATTACAAGCCAGAGAATGTCATTGTCACTAATGGCGGTAAGCATTCGCTTTACAACTTGAT
TGTGGCGCTGATTGATCCAGGTGATGAGGTAATTATCCCTGCTCCCTATTGGTTGAGTTATCCCGAAATGGTGACTCTGG
TAGGTGGGAAGTCGGTAATTGTCCCCACAGATGCTTCCACTGGTTATAAAATTACTCCCGAACAACTGCGGAAAGCTATT
ACCCCCAAAACCAAGCTATTTGTCCTCAACTCCCCATCTAACCCCACAGGAATGGTGTATACACCAGAGGAAATCAAGGC
TTTGGCTCAGGTAGTAGTTGATGCAGATATCTATGTTGTGTCTGATGAGATTTACGAAAAAATTCTCTATGATGGCGCAC
AGCATATCAGCATCGGTTCGCTAGGGAAGGAAATTTTTAACCGCACTTTGATTAGTAATGGCTTTGCCAAAGCTTATTCT
ATGACGGGGTGGCGCTTGGGGTATTTAGCCGGGCCAGTGGACATTATCAAGGCTGCTAGTTCCATTCAAGGGCATAGTAC
ATCGAATGTGTGTACCTTTGCTCAATATGGGGCGATCGCTGCTTTGGAAGATTCCCAAGACTGTGTGGAAGAAATGCGCC
AAGCTTTCGCTAAACGTCGTCAGGTAATGCTAGATCGACTCAACGCCATTCCCGGCTTGAGTACTGCAAAACCAGACGGT
GCATTTTATCTGTTTCCAGATATCAGCAAAACCGGTTTGAAATCCCTCGAATTTTGTGATGCTTTGATTGAAGAACACAA
GGTTGCAGTGATTCCAGGGATAGCTTTTGGTGCTGATGACAACATCCGCCTCTCCTACGCCACCGATTTGGCAACAATTG
AGAAAGGTTTGGATCGGTTAGAGAAGTTTGTCCGTTCTCGCATTTAG

Upstream 100 bases:

>100_bases
GATGATAAGTTGATTTGGGGAAAGTCCAAGGTGAAGGAACAGCGAGAAGGGATTCTGGGCTATTCTTAAATAGGTACGAG
ATTTGCCGAAGTAAGTAAGA

Downstream 100 bases:

>100_bases
TGAATCATCGGGTGTCAGCTACTGTCAAGTCAAAAATATCATACATCTTCTTATAGGGTGGGCATCTTGCCTACCCTAAA
TATTTGGGAGTTTTATTGTG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKLAARVSQVTPSITLAIAAKAKAMKAEGIDVCSFSAGEPDFDTPAHIKAAAAKALDEGKTKYGAAAGEPKLREAIAHKL
QKDNHLDYKPENVIVTNGGKHSLYNLIVALIDPGDEVIIPAPYWLSYPEMVTLVGGKSVIVPTDASTGYKITPEQLRKAI
TPKTKLFVLNSPSNPTGMVYTPEEIKALAQVVVDADIYVVSDEIYEKILYDGAQHISIGSLGKEIFNRTLISNGFAKAYS
MTGWRLGYLAGPVDIIKAASSIQGHSTSNVCTFAQYGAIAALEDSQDCVEEMRQAFAKRRQVMLDRLNAIPGLSTAKPDG
AFYLFPDISKTGLKSLEFCDALIEEHKVAVIPGIAFGADDNIRLSYATDLATIEKGLDRLEKFVRSRI

Sequences:

>Translated_388_residues
MKLAARVSQVTPSITLAIAAKAKAMKAEGIDVCSFSAGEPDFDTPAHIKAAAAKALDEGKTKYGAAAGEPKLREAIAHKL
QKDNHLDYKPENVIVTNGGKHSLYNLIVALIDPGDEVIIPAPYWLSYPEMVTLVGGKSVIVPTDASTGYKITPEQLRKAI
TPKTKLFVLNSPSNPTGMVYTPEEIKALAQVVVDADIYVVSDEIYEKILYDGAQHISIGSLGKEIFNRTLISNGFAKAYS
MTGWRLGYLAGPVDIIKAASSIQGHSTSNVCTFAQYGAIAALEDSQDCVEEMRQAFAKRRQVMLDRLNAIPGLSTAKPDG
AFYLFPDISKTGLKSLEFCDALIEEHKVAVIPGIAFGADDNIRLSYATDLATIEKGLDRLEKFVRSRI
>Mature_388_residues
MKLAARVSQVTPSITLAIAAKAKAMKAEGIDVCSFSAGEPDFDTPAHIKAAAAKALDEGKTKYGAAAGEPKLREAIAHKL
QKDNHLDYKPENVIVTNGGKHSLYNLIVALIDPGDEVIIPAPYWLSYPEMVTLVGGKSVIVPTDASTGYKITPEQLRKAI
TPKTKLFVLNSPSNPTGMVYTPEEIKALAQVVVDADIYVVSDEIYEKILYDGAQHISIGSLGKEIFNRTLISNGFAKAYS
MTGWRLGYLAGPVDIIKAASSIQGHSTSNVCTFAQYGAIAALEDSQDCVEEMRQAFAKRRQVMLDRLNAIPGLSTAKPDG
AFYLFPDISKTGLKSLEFCDALIEEHKVAVIPGIAFGADDNIRLSYATDLATIEKGLDRLEKFVRSRI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=29.5918367346939, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=29.5918367346939, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI56713254, Length=354, Percent_Identity=28.8135593220339, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI56713256, Length=354, Percent_Identity=28.8135593220339, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=28.7128712871287, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4507369, Length=379, Percent_Identity=24.0105540897098, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI149944424, Length=256, Percent_Identity=25.390625, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI215599424, Length=362, Percent_Identity=21.2707182320442, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI19263340, Length=362, Percent_Identity=21.2707182320442, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI187936925, Length=242, Percent_Identity=28.9256198347107, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI14211921, Length=242, Percent_Identity=28.9256198347107, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4885351, Length=348, Percent_Identity=21.551724137931, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786816, Length=390, Percent_Identity=28.974358974359, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788722, Length=396, Percent_Identity=29.5454545454545, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=28.7153652392947, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787909, Length=371, Percent_Identity=22.911051212938, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790797, Length=188, Percent_Identity=26.063829787234, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787710, Length=330, Percent_Identity=20, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=336, Percent_Identity=26.7857142857143, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=427, Percent_Identity=26.6978922716628, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=427, Percent_Identity=26.6978922716628, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=305, Percent_Identity=28.1967213114754, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=26.972010178117, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6323118, Length=364, Percent_Identity=22.5274725274725, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=345, Percent_Identity=22.8985507246377, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573069, Length=421, Percent_Identity=24.4655581947743, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24646114, Length=421, Percent_Identity=24.4655581947743, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573067, Length=421, Percent_Identity=24.4655581947743, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28573065, Length=421, Percent_Identity=24.4655581947743, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI18859735, Length=360, Percent_Identity=24.4444444444444, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356535, Length=324, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641770, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641760, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641768, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641766, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641764, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551451, Length=387, Percent_Identity=24.5478036175711, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41939; Mature: 41939

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAARVSQVTPSITLAIAAKAKAMKAEGIDVCSFSAGEPDFDTPAHIKAAAAKALDEGK
CCHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
TKYGAAAGEPKLREAIAHKLQKDNHLDYKPENVIVTNGGKHSLYNLIVALIDPGDEVIIP
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEEEEECCCCCEEEC
APYWLSYPEMVTLVGGKSVIVPTDASTGYKITPEQLRKAITPKTKLFVLNSPSNPTGMVY
CCHHCCCCCEEEEECCCEEEEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCEEE
TPEEIKALAQVVVDADIYVVSDEIYEKILYDGAQHISIGSLGKEIFNRTLISNGFAKAYS
CHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHH
MTGWRLGYLAGPVDIIKAASSIQGHSTSNVCTFAQYGAIAALEDSQDCVEEMRQAFAKRR
CCCEEEHHHCCHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
QVMLDRLNAIPGLSTAKPDGAFYLFPDISKTGLKSLEFCDALIEEHKVAVIPGIAFGADD
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCEEECCCC
NIRLSYATDLATIEKGLDRLEKFVRSRI
CEEEEEHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLAARVSQVTPSITLAIAAKAKAMKAEGIDVCSFSAGEPDFDTPAHIKAAAAKALDEGK
CCHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCC
TKYGAAAGEPKLREAIAHKLQKDNHLDYKPENVIVTNGGKHSLYNLIVALIDPGDEVIIP
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEEEEECCCCCEEEC
APYWLSYPEMVTLVGGKSVIVPTDASTGYKITPEQLRKAITPKTKLFVLNSPSNPTGMVY
CCHHCCCCCEEEEECCCEEEEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCEEE
TPEEIKALAQVVVDADIYVVSDEIYEKILYDGAQHISIGSLGKEIFNRTLISNGFAKAYS
CHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHHHH
MTGWRLGYLAGPVDIIKAASSIQGHSTSNVCTFAQYGAIAALEDSQDCVEEMRQAFAKRR
CCCEEEHHHCCHHHHHHHHHHCCCCCCCCEEEHHHCCCEEEECCCHHHHHHHHHHHHHHH
QVMLDRLNAIPGLSTAKPDGAFYLFPDISKTGLKSLEFCDALIEEHKVAVIPGIAFGADD
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCEEECCCC
NIRLSYATDLATIEKGLDRLEKFVRSRI
CEEEEEHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]