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The map label for this gene is 75908277

Identifier: 75908277

GI number: 75908277

Start: 2544346

End: 2545878

Strand: Direct

Name: 75908277

Synonym: Ava_2056

Alternate gene names: NA

Gene position: 2544346-2545878 (Clockwise)

Preceding gene: 75908276

Following gene: 75908278

Centisome position: 39.97

GC content: 42.07

Gene sequence:

>1533_bases
ATGACAGAAACGACTCTCCCACCCTTAATTCAGCAGATGTTACAACCAGGATTTTATCCTCATGAAGTAACAGAACCTAT
TCAACTAATTCAGACTCATGTTTCTTCTGTGTTACTCACAGGAGAGTATGCCTATAAACTAAAAAAACCAGTGAATTTTG
GCTTTTTGGATTTCTCCACTTTAGAAAAGCGACAACATTTTTGTCAGGAAGAACTGCGCTTGAATCAACGAGGAGCAGCT
GAATTATATTTAGAAGTTTTACCAATCAGTTTGGTAGGTGAGCAATATACTCTAGGGGGAACTGGTGAGGCTGTCGAGTA
TGTGCTGAAGATGCGCCAGTTTCCCCAGGATGGCTTATTCAGTGAACTTTTTGCCCAAGGTAAACTCACTGAGTCACACC
TAGAAGAATTAGGCAAGGTCGTGGCTCAATACCATGCTAAAACTGAGACGAATGATTATATTCGCAGTTTTGGAGAAGTT
CCTCAAGTGCAGGCTGCATTTGATGAAAATTATCAGCAAACTGAGAAATATATCGGTGGACCCCAAACACAGTTGCAATT
TGACGAAACTAAAGCCTACACCGAGCGTTTTTTCGCAGAAAAACAAGAATTATTCCAGCGCCGAATCCAAAATAACTATA
TTCGGGAATGTCATGGAGACTTACACCTGAGAAATATCTGTCTATGGCAAGATAAAATTCTTCTGTTTGATTGTATTGAA
TTTAACGAACCTTTCCGCTTTGTTGATGTCATGTTCGATGTCGCCTATGCGGTGATGGATTTGGATGCACAGCAACGCCC
AGACCTGAGTAACGCATATTTGAATACCTATCTAGAGCAGACTGGCGACTGGGAAGGGTTAGAAGTGCTACCCATATACT
TAAATCGTCAATCTTATGTGCGAGCTAAAGTAACTTCATTTTTATTGGATGACCCCAGCGTCCCCGCGACGGTGAAGGAA
GAAGCGACGAAAACAGCCTCTACATACTACAAACTGGCGTGGGAATATACCAAACCCAAACAAGGAAAACTTATCTTAAT
GTCCGGGTTATCTGGTTCTGGGAAGAGTACGACTGCAAAATATTTAGCCCGTCAACTAGATGCAATTCAAATTCGCTCAG
ATGCAGTCCGCAAACACTTGGGGGGAATTTCTCTGTGGGAACGTGGTGGTGATGACTTGTATACACCCGAAATGACCCAG
AAAACCTATGCAAGGTTATTAAACTTGGGGACTATACTAGCTAATCAAGGTTACACAGTAATTTTGGATGCTAAATATGA
TAAACAAAATTTACGCCAAGAGGCGATCGCTCAAGCCGAAAAACATCACCTCCCCCTCCAGATTATTCACTGCACAGCAC
CCATAGAAGTTATACAAGAACGCCTAATAAAGCGTACAGGCGATATTGCCGATGCTACAGTTGATTTGTTATCTTCCCAA
CTCCAGCAAACTGAACCCTTTACCGACCAAGAAAAACCTTACGTGCAAACTTGGGACACAACTCAACCACCACACGTAAT
TGGTAATCGGTAA

Upstream 100 bases:

>100_bases
AAATGCTTGTGAGTTCGACGTTGAGGCTTTTACTCTCCTAAAAAAAGTACCATAATCAAGGTTTCAGCATATCCTGAACT
CAGGTTAATTTAAAATTTCT

Downstream 100 bases:

>100_bases
TTTACCGAAAGCTTATTTATGGGGAAACAAGTGTAGGTTAAAAACGTTACCCCTACACCCCTACACCCCTACACCCCTAC
ACCCCTAGTTCATTTATGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MTETTLPPLIQQMLQPGFYPHEVTEPIQLIQTHVSSVLLTGEYAYKLKKPVNFGFLDFSTLEKRQHFCQEELRLNQRGAA
ELYLEVLPISLVGEQYTLGGTGEAVEYVLKMRQFPQDGLFSELFAQGKLTESHLEELGKVVAQYHAKTETNDYIRSFGEV
PQVQAAFDENYQQTEKYIGGPQTQLQFDETKAYTERFFAEKQELFQRRIQNNYIRECHGDLHLRNICLWQDKILLFDCIE
FNEPFRFVDVMFDVAYAVMDLDAQQRPDLSNAYLNTYLEQTGDWEGLEVLPIYLNRQSYVRAKVTSFLLDDPSVPATVKE
EATKTASTYYKLAWEYTKPKQGKLILMSGLSGSGKSTTAKYLARQLDAIQIRSDAVRKHLGGISLWERGGDDLYTPEMTQ
KTYARLLNLGTILANQGYTVILDAKYDKQNLRQEAIAQAEKHHLPLQIIHCTAPIEVIQERLIKRTGDIADATVDLLSSQ
LQQTEPFTDQEKPYVQTWDTTQPPHVIGNR

Sequences:

>Translated_510_residues
MTETTLPPLIQQMLQPGFYPHEVTEPIQLIQTHVSSVLLTGEYAYKLKKPVNFGFLDFSTLEKRQHFCQEELRLNQRGAA
ELYLEVLPISLVGEQYTLGGTGEAVEYVLKMRQFPQDGLFSELFAQGKLTESHLEELGKVVAQYHAKTETNDYIRSFGEV
PQVQAAFDENYQQTEKYIGGPQTQLQFDETKAYTERFFAEKQELFQRRIQNNYIRECHGDLHLRNICLWQDKILLFDCIE
FNEPFRFVDVMFDVAYAVMDLDAQQRPDLSNAYLNTYLEQTGDWEGLEVLPIYLNRQSYVRAKVTSFLLDDPSVPATVKE
EATKTASTYYKLAWEYTKPKQGKLILMSGLSGSGKSTTAKYLARQLDAIQIRSDAVRKHLGGISLWERGGDDLYTPEMTQ
KTYARLLNLGTILANQGYTVILDAKYDKQNLRQEAIAQAEKHHLPLQIIHCTAPIEVIQERLIKRTGDIADATVDLLSSQ
LQQTEPFTDQEKPYVQTWDTTQPPHVIGNR
>Mature_509_residues
TETTLPPLIQQMLQPGFYPHEVTEPIQLIQTHVSSVLLTGEYAYKLKKPVNFGFLDFSTLEKRQHFCQEELRLNQRGAAE
LYLEVLPISLVGEQYTLGGTGEAVEYVLKMRQFPQDGLFSELFAQGKLTESHLEELGKVVAQYHAKTETNDYIRSFGEVP
QVQAAFDENYQQTEKYIGGPQTQLQFDETKAYTERFFAEKQELFQRRIQNNYIRECHGDLHLRNICLWQDKILLFDCIEF
NEPFRFVDVMFDVAYAVMDLDAQQRPDLSNAYLNTYLEQTGDWEGLEVLPIYLNRQSYVRAKVTSFLLDDPSVPATVKEE
ATKTASTYYKLAWEYTKPKQGKLILMSGLSGSGKSTTAKYLARQLDAIQIRSDAVRKHLGGISLWERGGDDLYTPEMTQK
TYARLLNLGTILANQGYTVILDAKYDKQNLRQEAIAQAEKHHLPLQIIHCTAPIEVIQERLIKRTGDIADATVDLLSSQL
QQTEPFTDQEKPYVQTWDTTQPPHVIGNR

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 58508; Mature: 58377

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTLPPLIQQMLQPGFYPHEVTEPIQLIQTHVSSVLLTGEYAYKLKKPVNFGFLDFST
CCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCCCCCHHH
LEKRQHFCQEELRLNQRGAAELYLEVLPISLVGEQYTLGGTGEAVEYVLKMRQFPQDGLF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCHH
SELFAQGKLTESHLEELGKVVAQYHAKTETNDYIRSFGEVPQVQAAFDENYQQTEKYIGG
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCC
PQTQLQFDETKAYTERFFAEKQELFQRRIQNNYIRECHGDLHLRNICLWQDKILLFDCIE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCEEEECC
FNEPFRFVDVMFDVAYAVMDLDAQQRPDLSNAYLNTYLEQTGDWEGLEVLPIYLNRQSYV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHH
RAKVTSFLLDDPSVPATVKEEATKTASTYYKLAWEYTKPKQGKLILMSGLSGSGKSTTAK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEECCCCCCCHHHHH
YLARQLDAIQIRSDAVRKHLGGISLWERGGDDLYTPEMTQKTYARLLNLGTILANQGYTV
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
ILDAKYDKQNLRQEAIAQAEKHHLPLQIIHCTAPIEVIQERLIKRTGDIADATVDLLSSQ
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
LQQTEPFTDQEKPYVQTWDTTQPPHVIGNR
HHHCCCCCCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TETTLPPLIQQMLQPGFYPHEVTEPIQLIQTHVSSVLLTGEYAYKLKKPVNFGFLDFST
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCCCCCHHH
LEKRQHFCQEELRLNQRGAAELYLEVLPISLVGEQYTLGGTGEAVEYVLKMRQFPQDGLF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCCHH
SELFAQGKLTESHLEELGKVVAQYHAKTETNDYIRSFGEVPQVQAAFDENYQQTEKYIGG
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCHHHHHHHCCC
PQTQLQFDETKAYTERFFAEKQELFQRRIQNNYIRECHGDLHLRNICLWQDKILLFDCIE
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEECCCCCEEEECC
FNEPFRFVDVMFDVAYAVMDLDAQQRPDLSNAYLNTYLEQTGDWEGLEVLPIYLNRQSYV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHH
RAKVTSFLLDDPSVPATVKEEATKTASTYYKLAWEYTKPKQGKLILMSGLSGSGKSTTAK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEECCCCCCCHHHHH
YLARQLDAIQIRSDAVRKHLGGISLWERGGDDLYTPEMTQKTYARLLNLGTILANQGYTV
HHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEE
ILDAKYDKQNLRQEAIAQAEKHHLPLQIIHCTAPIEVIQERLIKRTGDIADATVDLLSSQ
EEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
LQQTEPFTDQEKPYVQTWDTTQPPHVIGNR
HHHCCCCCCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]