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The map label for this gene is aprX [H]

Identifier: 75908239

GI number: 75908239

Start: 2498796

End: 2500532

Strand: Direct

Name: aprX [H]

Synonym: Ava_2018

Alternate gene names: 75908239

Gene position: 2498796-2500532 (Clockwise)

Preceding gene: 75908237

Following gene: 75908240

Centisome position: 39.25

GC content: 45.02

Gene sequence:

>1737_bases
ATGCGACATGAAAAACTTGCGCCTGCATTGTTATTAGCCTATCAAGACCTTCAAAATGAAGGACAGACAGCTTTAATAAA
GCATAGGCATTTTCTAGGTATAATTGCCCCTAAAACAGTTATCAAACCTACCAAAAGTATTATCTTTATCTACTGTGATG
CTGACGCTGACTTAAGCCATTTGTCACAGTACGGGGTGGAAGTAAATCAAAATTCCGGCAGTGTTCGTACAGCTTTCTTA
CCCTTAGAAAATCTCGCCGCCATATCAGAAGAAGCCGCCATCCACAGAATTAAACCTTCACGTCAACTCAAGCTGCGGAT
GGATGTTGCACCCCAAGCCGTGCAATTGCCAGATTTTCATGGCAAAACAGGATTGACTGGTAAAGGTGTCATCATCGGCA
TTATCGACACAGGAATCGATGCCAAACACCATGCTTTTACTGGCCGGATTTTGCGGATTTGGGATCAAACTCTACCAGGC
CCAGGGGTAAATGAGGGTGGCTACGGTGCGGAATTTACAGAAACACAACTTACCATTTCTCAAGATACGGCAGGTCATGG
TACTCATGTTGCTGGCATTGCGGCTGGTGCGGATGCTACCTATCGCGGCGTAGCACCAGAGGCCGAGTTAGTCATTGTCA
AATCTGATTTACAAGATGCCCATATTGCCGATGGCATCCGTTATATTTTTCGGGTAGCTGGTGAGTTGGGAAGACCAGCC
GTAGTTAACATTAGTTTAGGTAATCATAGTGATGCCCATGATGGCACTGATTCTCTATCACAAATTATTGATGCAGAATC
AGGTTCAGGCAAAATTGTATGTTGCGCTGCGGGTAATGAAGGTAACTACAATATTCACGGTCAAGCAAACATTCCCAGTG
GACGCAACCGAGGAATGCGCTTTCATGTCCCCTTAAATCAAATTGGTATAGTTTGGTTAAATGCTTGGTATGCCAGTAGT
GGCCAATTGGAAGTATCGGTACAGAGTCCCAACGGTTTTGTTAGTCCTTGGCAAAAAATTATCACTGACGGCAATCCTAG
CCAAAGTTATAATTTACCTGATTCTCAGGTAGAAATTGTCACCCCAGGCCCAGACCCAGCCAATGGTGATTACAATGTCT
TTGTACAGATTCGTGGTCAGGGTAAATCACCAGTACAAGGCGGTGTGTGGCAATTGCGATCGCGCAACACTTCCTCATCT
GATACTAGACTGGATGTGTGGACACTGGACGATACATCCTCAGTGTTTTTTACAGGTAAAAGTGTCAAGGATGCCTTAAA
AATTGGTTCTCCAGGCTGCGCTAAAAGTGCGGTGACGGTTGCTGCTTACACCACCAAAGCCAAGTTTCAAGATATAGATG
GTCAGATTCAAGAAATGGGGCTTGATTTAAACACCATTGCGGATTTTAGTAGTGAAGGCCCTCTGCGGAACAATACCCAA
AAACCAGATGTGGCTGCACCAGGGGCAATGATTGTATCTGCACTTTCTGGTTATGCTCATAGTGATGATCGCTCAATGAC
CATTAATCCCCAGTTTATCGCCATGTCTGGTACAAGTATGGCTGCACCGTTCATCACCGGCTTAATCGCCTTACTTCTGC
AACGCAACCCTAGCCTAGACCCGGAGGCAATTAAAGACTTACTACGTCAAAGTAGTTCTATCCCTGGTAAACCTCCTGGT
ACATTTGACCCCAAATGGGGTTTTGGGCTGATTAATGCTGCAAAATTAATCGGCTGA

Upstream 100 bases:

>100_bases
TTCCTCCAATTACCAATTACTTACTACCAATTACCCCATCCAGAGTCGCATCAATACCAGCACTAATTAATTTAAATACT
CTTGTAAAATTGGTGTCAAA

Downstream 100 bases:

>100_bases
GATTGAGGGTTTTTAGCCAAAAAGTCATGATTATGGATTACCAAAAGTTAGATGCAGCCCTGACTATGGCGCTAAATGAA
TCGCCAGAAGGCAGTTTAGA

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MRHEKLAPALLLAYQDLQNEGQTALIKHRHFLGIIAPKTVIKPTKSIIFIYCDADADLSHLSQYGVEVNQNSGSVRTAFL
PLENLAAISEEAAIHRIKPSRQLKLRMDVAPQAVQLPDFHGKTGLTGKGVIIGIIDTGIDAKHHAFTGRILRIWDQTLPG
PGVNEGGYGAEFTETQLTISQDTAGHGTHVAGIAAGADATYRGVAPEAELVIVKSDLQDAHIADGIRYIFRVAGELGRPA
VVNISLGNHSDAHDGTDSLSQIIDAESGSGKIVCCAAGNEGNYNIHGQANIPSGRNRGMRFHVPLNQIGIVWLNAWYASS
GQLEVSVQSPNGFVSPWQKIITDGNPSQSYNLPDSQVEIVTPGPDPANGDYNVFVQIRGQGKSPVQGGVWQLRSRNTSSS
DTRLDVWTLDDTSSVFFTGKSVKDALKIGSPGCAKSAVTVAAYTTKAKFQDIDGQIQEMGLDLNTIADFSSEGPLRNNTQ
KPDVAAPGAMIVSALSGYAHSDDRSMTINPQFIAMSGTSMAAPFITGLIALLLQRNPSLDPEAIKDLLRQSSSIPGKPPG
TFDPKWGFGLINAAKLIG

Sequences:

>Translated_578_residues
MRHEKLAPALLLAYQDLQNEGQTALIKHRHFLGIIAPKTVIKPTKSIIFIYCDADADLSHLSQYGVEVNQNSGSVRTAFL
PLENLAAISEEAAIHRIKPSRQLKLRMDVAPQAVQLPDFHGKTGLTGKGVIIGIIDTGIDAKHHAFTGRILRIWDQTLPG
PGVNEGGYGAEFTETQLTISQDTAGHGTHVAGIAAGADATYRGVAPEAELVIVKSDLQDAHIADGIRYIFRVAGELGRPA
VVNISLGNHSDAHDGTDSLSQIIDAESGSGKIVCCAAGNEGNYNIHGQANIPSGRNRGMRFHVPLNQIGIVWLNAWYASS
GQLEVSVQSPNGFVSPWQKIITDGNPSQSYNLPDSQVEIVTPGPDPANGDYNVFVQIRGQGKSPVQGGVWQLRSRNTSSS
DTRLDVWTLDDTSSVFFTGKSVKDALKIGSPGCAKSAVTVAAYTTKAKFQDIDGQIQEMGLDLNTIADFSSEGPLRNNTQ
KPDVAAPGAMIVSALSGYAHSDDRSMTINPQFIAMSGTSMAAPFITGLIALLLQRNPSLDPEAIKDLLRQSSSIPGKPPG
TFDPKWGFGLINAAKLIG
>Mature_578_residues
MRHEKLAPALLLAYQDLQNEGQTALIKHRHFLGIIAPKTVIKPTKSIIFIYCDADADLSHLSQYGVEVNQNSGSVRTAFL
PLENLAAISEEAAIHRIKPSRQLKLRMDVAPQAVQLPDFHGKTGLTGKGVIIGIIDTGIDAKHHAFTGRILRIWDQTLPG
PGVNEGGYGAEFTETQLTISQDTAGHGTHVAGIAAGADATYRGVAPEAELVIVKSDLQDAHIADGIRYIFRVAGELGRPA
VVNISLGNHSDAHDGTDSLSQIIDAESGSGKIVCCAAGNEGNYNIHGQANIPSGRNRGMRFHVPLNQIGIVWLNAWYASS
GQLEVSVQSPNGFVSPWQKIITDGNPSQSYNLPDSQVEIVTPGPDPANGDYNVFVQIRGQGKSPVQGGVWQLRSRNTSSS
DTRLDVWTLDDTSSVFFTGKSVKDALKIGSPGCAKSAVTVAAYTTKAKFQDIDGQIQEMGLDLNTIADFSSEGPLRNNTQ
KPDVAAPGAMIVSALSGYAHSDDRSMTINPQFIAMSGTSMAAPFITGLIALLLQRNPSLDPEAIKDLLRQSSSIPGKPPG
TFDPKWGFGLINAAKLIG

Specific function: Displays serine protease activity. Seems to have a broad substrate specificity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Is leaked to the culture medium during the late stationary phase owing to cell lysis [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 61662; Mature: 61662

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHEKLAPALLLAYQDLQNEGQTALIKHRHFLGIIAPKTVIKPTKSIIFIYCDADADLSH
CCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCHHCCCCCEEEEEEECCCCCHHH
LSQYGVEVNQNSGSVRTAFLPLENLAAISEEAAIHRIKPSRQLKLRMDVAPQAVQLPDFH
HHHCCCEEECCCCCEEEEEECHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEECCCCC
GKTGLTGKGVIIGIIDTGIDAKHHAFTGRILRIWDQTLPGPGVNEGGYGAEFTETQLTIS
CCCCCCCCCEEEEEEECCCCCCCHHHHCHHEEEEHHCCCCCCCCCCCCCCEEEEEEEEEE
QDTAGHGTHVAGIAAGADATYRGVAPEAELVIVKSDLQDAHIADGIRYIFRVAGELGRPA
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCE
VVNISLGNHSDAHDGTDSLSQIIDAESGSGKIVCCAAGNEGNYNIHGQANIPSGRNRGMR
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEE
FHVPLNQIGIVWLNAWYASSGQLEVSVQSPNGFVSPWQKIITDGNPSQSYNLPDSQVEIV
EEECHHHEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEE
TPGPDPANGDYNVFVQIRGQGKSPVQGGVWQLRSRNTSSSDTRLDVWTLDDTSSVFFTGK
ECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEEECC
SVKDALKIGSPGCAKSAVTVAAYTTKAKFQDIDGQIQEMGLDLNTIADFSSEGPLRNNTQ
CHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCC
KPDVAAPGAMIVSALSGYAHSDDRSMTINPQFIAMSGTSMAAPFITGLIALLLQRNPSLD
CCCCCCCHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
PEAIKDLLRQSSSIPGKPPGTFDPKWGFGLINAAKLIG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MRHEKLAPALLLAYQDLQNEGQTALIKHRHFLGIIAPKTVIKPTKSIIFIYCDADADLSH
CCCHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCHHCCCCCEEEEEEECCCCCHHH
LSQYGVEVNQNSGSVRTAFLPLENLAAISEEAAIHRIKPSRQLKLRMDVAPQAVQLPDFH
HHHCCCEEECCCCCEEEEEECHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEECCCCC
GKTGLTGKGVIIGIIDTGIDAKHHAFTGRILRIWDQTLPGPGVNEGGYGAEFTETQLTIS
CCCCCCCCCEEEEEEECCCCCCCHHHHCHHEEEEHHCCCCCCCCCCCCCCEEEEEEEEEE
QDTAGHGTHVAGIAAGADATYRGVAPEAELVIVKSDLQDAHIADGIRYIFRVAGELGRPA
CCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCE
VVNISLGNHSDAHDGTDSLSQIIDAESGSGKIVCCAAGNEGNYNIHGQANIPSGRNRGMR
EEEEEECCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEE
FHVPLNQIGIVWLNAWYASSGQLEVSVQSPNGFVSPWQKIITDGNPSQSYNLPDSQVEIV
EEECHHHEEEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEE
TPGPDPANGDYNVFVQIRGQGKSPVQGGVWQLRSRNTSSSDTRLDVWTLDDTSSVFFTGK
ECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCEEEEECC
SVKDALKIGSPGCAKSAVTVAAYTTKAKFQDIDGQIQEMGLDLNTIADFSSEGPLRNNTQ
CHHHHHHCCCCCCCCCEEEEEEEECCCHHCCCCCHHHHHCCCHHHHHCCCCCCCCCCCCC
KPDVAAPGAMIVSALSGYAHSDDRSMTINPQFIAMSGTSMAAPFITGLIALLLQRNPSLD
CCCCCCCHHHHHHHHHCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
PEAIKDLLRQSSSIPGKPPGTFDPKWGFGLINAAKLIG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]