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The map label for this gene is bioD [H]

Identifier: 75908217

GI number: 75908217

Start: 2479494

End: 2480171

Strand: Direct

Name: bioD [H]

Synonym: Ava_1996

Alternate gene names: 75908217

Gene position: 2479494-2480171 (Clockwise)

Preceding gene: 75908216

Following gene: 75908218

Centisome position: 38.95

GC content: 43.66

Gene sequence:

>678_bases
TTGTTGAAGTCACTACTAATTACTGGAACTGATACAGAAGCTGGCAAAACTGCTTTGACTACAGTTTTGGCAGCTTACTG
TCAGAAATATTACCCCCAAGGCAGTTGGGGAATTATGAAACCAATTCAATCGGGAATTGGCGATCGCGAATGGTATCAAA
ATCTGTTTACACTAGAGCAAACAATCGCCGAAATTACACCTCTGCACTTTAGCGCACCTCTGGCTCCTCCCATCGCCGCC
GCCAAGGAAAATCGTTCTGTAGATTTAGCTATAGTTTGGCAGACTTTAACCCAGTTGCGATCGCGTCTTGATGTGTTGCT
AATTGAAGCTTTAGGTGGTTTGGGTTCACCAGTCACCGACGAGTTAACAGTGGCAGATTTAGCCGGGGAATGGCGCTTAC
CTACAGTATTAGTAGTACCTGTAAAATTAGGTTCCCTGGGACACGCTGTAGCGAATGTGGCATTGGCTAGACAAACGCGA
GTGGATCTCAAAGGGATTGTGTTGAACTGTACACAACCTATATCTGATGAAGAAATCGCCGACTTAACACCAAAAGATTT
AATTCAATCCCTCACGAATATTCCAGTCTTAGGCTGTCTACCTTATGTAGATAACTTCTCTGATTTCGATCAACTGGTGC
AAATCGCCTCAAATTTAGATTTAGAAACACTGGAGTAG

Upstream 100 bases:

>100_bases
CAGTGTATTACAATATTTGTGAGTTCTTAGCGATCAAAACTCTGAAGTAATGCGATTTACTTCATCACATACCCGTCTTC
ATTCAGATTATTAAACCAGA

Downstream 100 bases:

>100_bases
GTGAGTGTAGGGGTGTAAGGGTGTAGGGGTTAGTGAAATGATGATTCTCTCGTTAGTTTGAGAGTCATAATTTACCCCTT
GGTAAAAAGTCCCCAATCCC

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGHAVANVALARQTR
VDLKGIVLNCTQPISDEEIADLTPKDLIQSLTNIPVLGCLPYVDNFSDFDQLVQIASNLDLETLE

Sequences:

>Translated_225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGHAVANVALARQTR
VDLKGIVLNCTQPISDEEIADLTPKDLIQSLTNIPVLGCLPYVDNFSDFDQLVQIASNLDLETLE
>Mature_225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGHAVANVALARQTR
VDLKGIVLNCTQPISDEEIADLTPKDLIQSLTNIPVLGCLPYVDNFSDFDQLVQIASNLDLETLE

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=214, Percent_Identity=30.3738317757009, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24421; Mature: 24421

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQ
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
TIAEITPLHFSAPLAPPIAAAKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTD
HHHHHCCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELTVADLAGEWRLPTVLVVPVKLGSLGHAVANVALARQTRVDLKGIVLNCTQPISDEEIA
CHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
DLTPKDLIQSLTNIPVLGCLPYVDNFSDFDQLVQIASNLDLETLE
CCCHHHHHHHHHCCCCEEHHHHHCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQ
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
TIAEITPLHFSAPLAPPIAAAKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTD
HHHHHCCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELTVADLAGEWRLPTVLVVPVKLGSLGHAVANVALARQTRVDLKGIVLNCTQPISDEEIA
CHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHH
DLTPKDLIQSLTNIPVLGCLPYVDNFSDFDQLVQIASNLDLETLE
CCCHHHHHHHHHCCCCEEHHHHHCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA