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The map label for this gene is galE [H]

Identifier: 75908178

GI number: 75908178

Start: 2433225

End: 2434223

Strand: Direct

Name: galE [H]

Synonym: Ava_1957

Alternate gene names: 75908178

Gene position: 2433225-2434223 (Clockwise)

Preceding gene: 75908172

Following gene: 75908181

Centisome position: 38.22

GC content: 43.84

Gene sequence:

>999_bases
ATGTCGCCTGGAAAGCCCAGCATCTTGGTAACGGGGGGAGCAGGATATATTGGTTCGCACACTGTCCTGGCTCTCAAGCA
AGCAGGTTACGACGTGGTAATACTAGATAATTTGGTCTATGGACATCGTGATTTAGTAGAAAAAGTTTTACAAGTAGAAT
TGGTGGTGGGTGATACAGGCGATCGCTCTTTGTTAGATGAGTTATTTAAATCCCGTCATTTTGATGCAGTGATGCACTTT
TCCGCTTACGCTTATGTAGGCGAATCTGTTAGTGATCCTGCCAAGTACTATCGCAATAATGTTTTAGGCACATTAACCTT
ATTAGAAGCGATGCTGGCTGCTTCAATTAATAAGTTTGTCTTTTCTTCCACTTGTGCCACTTATGGAGTGCCAAAAAGTG
TTCCCATTCCCGAAGATCATCCCCAAGACCCCATCAATCCTTATGGTGCGACTAAGTTAATGGTGGAAAGGATTTTGGCG
GATTTCGATGTAGCTTATGGTTTGAAATCAGTCCGTTTCCGTTACTTTAATGCTGCTGGTGCTAATCCTGATGGATTGCT
AGGTGAGGATCACAACCCCGAAACTCATTTAATCCCTCTAGTACTACTAACAGCTTTAGGTAAACGTAAATCCATCTCTA
TTTTCGGCACTGATTATCCCACACCCGATGGCACTTGTATTCGGGATTATATCCACGTTAACGACTTAGCCGATGCCCAC
GTTTTGGGATTGGAATATTTGTTAAAAGGTGGAGATAGCGAAGTTTTTAACTTGGGTAATGGCCAAGGTTTCTCTGTCAG
AGAAGTAATTGCAGCTGGTGAACAAGTCACAGGATTACCCATAGCCGTTGAAGAATGCGATCGCCGTCCCGGAGATCCCC
CCAGTCTGATTGGTAGTGGTGAGAAAGCCAGAAAAATCCTTGGCTGGCAACCAAATTACCCATCAATCAAAGATATTGTT
GCCCATGCTTGGCAATGGCATCAGAAGCGGCATCAATAA

Upstream 100 bases:

>100_bases
CTGGGTGTAAGGGTGTAGGGGTGTAGGGGTGAATTCCGCAGGGTACTTTCTACCTTTCTTGCTAAATTAATTGAGTAGTT
GTCACTCAAAAGGAAAAACT

Downstream 100 bases:

>100_bases
CAATTCAAAATTCAAAATTCAAAATTCAAAATACCCTTCGGGTTCTCCGCAGGAGTACAAAATTCAAAATTACTAGATAC
CCGACTTCTTGAAGAAGTCG

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRSLLDELFKSRHFDAVMHF
SAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKSVPIPEDHPQDPINPYGATKLMVERILA
DFDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKSISIFGTDYPTPDGTCIRDYIHVNDLADAH
VLGLEYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPIAVEECDRRPGDPPSLIGSGEKARKILGWQPNYPSIKDIV
AHAWQWHQKRHQ

Sequences:

>Translated_332_residues
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRSLLDELFKSRHFDAVMHF
SAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKSVPIPEDHPQDPINPYGATKLMVERILA
DFDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKSISIFGTDYPTPDGTCIRDYIHVNDLADAH
VLGLEYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPIAVEECDRRPGDPPSLIGSGEKARKILGWQPNYPSIKDIV
AHAWQWHQKRHQ
>Mature_331_residues
SPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTGDRSLLDELFKSRHFDAVMHFS
AYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFVFSSTCATYGVPKSVPIPEDHPQDPINPYGATKLMVERILAD
FDVAYGLKSVRFRYFNAAGANPDGLLGEDHNPETHLIPLVLLTALGKRKSISIFGTDYPTPDGTCIRDYIHVNDLADAHV
LGLEYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPIAVEECDRRPGDPPSLIGSGEKARKILGWQPNYPSIKDIVA
HAWQWHQKRHQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=39.1691394658754, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=39.1691394658754, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=39.1691394658754, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI7657641, Length=334, Percent_Identity=26.0479041916168, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI42516563, Length=319, Percent_Identity=25.3918495297806, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=42.1686746987952, Blast_Score=251, Evalue=4e-68,
Organism=Escherichia coli, GI1788353, Length=336, Percent_Identity=30.0595238095238, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994969, Length=248, Percent_Identity=33.8709677419355, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790049, Length=271, Percent_Identity=30.2583025830258, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=38.5964912280702, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=38.6627906976744, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17568069, Length=267, Percent_Identity=27.7153558052434, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=317, Percent_Identity=25.8675078864353, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=349, Percent_Identity=24.6418338108883, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133901786, Length=291, Percent_Identity=25.4295532646048, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539422, Length=291, Percent_Identity=25.4295532646048, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133901788, Length=291, Percent_Identity=25.4295532646048, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133901790, Length=355, Percent_Identity=24.7887323943662, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17539424, Length=291, Percent_Identity=25.4295532646048, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=336, Percent_Identity=41.6666666666667, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=40.3458213256484, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=26.5625, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36242; Mature: 36110

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTG
CCCCCCCEEEECCCCCCCCHHEEEEHHCCCEEEEECCHHHCCHHHHHHHHEEEEEEECCC
DRSLLDELFKSRHFDAVMHFSAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFV
CHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FSSTCATYGVPKSVPIPEDHPQDPINPYGATKLMVERILADFDVAYGLKSVRFRYFNAAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
ANPDGLLGEDHNPETHLIPLVLLTALGKRKSISIFGTDYPTPDGTCIRDYIHVNDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCHHH
VLGLEYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPIAVEECDRRPGDPPSLIGSG
HHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCC
EKARKILGWQPNYPSIKDIVAHAWQWHQKRHQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPGKPSILVTGGAGYIGSHTVLALKQAGYDVVILDNLVYGHRDLVEKVLQVELVVGDTG
CCCCCCEEEECCCCCCCCHHEEEEHHCCCEEEEECCHHHCCHHHHHHHHEEEEEEECCC
DRSLLDELFKSRHFDAVMHFSAYAYVGESVSDPAKYYRNNVLGTLTLLEAMLAASINKFV
CHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FSSTCATYGVPKSVPIPEDHPQDPINPYGATKLMVERILADFDVAYGLKSVRFRYFNAAG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
ANPDGLLGEDHNPETHLIPLVLLTALGKRKSISIFGTDYPTPDGTCIRDYIHVNDLADAH
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHEEECCCCCHHH
VLGLEYLLKGGDSEVFNLGNGQGFSVREVIAAGEQVTGLPIAVEECDRRPGDPPSLIGSG
HHHHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCC
EKARKILGWQPNYPSIKDIVAHAWQWHQKRHQ
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]