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The map label for this gene is ctaC [H]

Identifier: 75676498

GI number: 75676498

Start: 2530525

End: 2531259

Strand: Direct

Name: ctaC [H]

Synonym: Nwi_2313

Alternate gene names: 75676498

Gene position: 2530525-2531259 (Clockwise)

Preceding gene: 75676497

Following gene: 75676499

Centisome position: 74.38

GC content: 67.48

Gene sequence:

>735_bases
GTGGACTGGCCTGGAGGCGGGCCTGTGACGGTCGCCGCCCGCCTGCGTCGAAGGCCGCTTGCGGGTCTCGCCAGTTTGAC
GATCCTGTCCGGTTGCACGGGGCCGCTTTCAGCGCTCGACCCTGCCGGACCGGCAGCCGCTTCCACCGCAACGCTATGGT
GGATCATGTTCTCGGGGGCCGCCGTCCTGTCGCTTCTGATGGCGGCCCTGATCGCGCTGGCGTTCCTCAAACCGGGCATC
GCCTCGATGTGGTCGTCGAGAAGCTGGATCATCTATGGCGGCCTCGTCATGCCTGGCGCGGTGCTGTCGGCCCTGCTGAT
CGCGGCGCTCGTGCTGGGCGAGCGCATGATCGTGCACCCACTGGAGCAACCTCCACTGAAGGTCGCGGCGCAGGCGCGCC
AATGGACCTGGAGCTTCGCCTACCCGGACAGCCGGCGAGCCACGCTATCCGTGAACGTTCTGCATATCCCCGCGGGCGAG
CCGGTCGACGTGATCGTCACCACGAAGGACGTAATCCACTCGTTCTGGGTGCCCCGGCTCGGCGGCAAGATAGACGCCAT
CCCCGGCCACCGGAACGTTGTCCGGCTCCAGGCGGATCGCCCGGGCGTTTATGGCGGTGTCTGCGCCGAGTTCTGCGGCG
CAGGCCATTCCGCCATGCGGTTCACGGTTCTGGCCCATGAGCCCGAGGAGTTCGCCACGATCATGGCGGGCGCGATTGAA
GAGGCCAGGCGATGA

Upstream 100 bases:

>100_bases
TCCTTCTGGTGCTGGCAAAGCCATCGTTTCCGCTGGACGCTCTGCCTGACGCCATCTCGCGGCCGGGCGCGCTGAGGGAG
CTTTTCGCTCCCCTCCTCCG

Downstream 100 bases:

>100_bases
GCGGGCGGGTGGCGACGCCGCTGCGGCTCCACAGGCAGCTCAACGAAATCTGGGCCAGCGGACGCGGTGTGAAACGGCTC
GCGGCGGTCAACCACAGCGT

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDWPGGGPVTVAARLRRRPLAGLASLTILSGCTGPLSALDPAGPAAASTATLWWIMFSGAAVLSLLMAALIALAFLKPGI
ASMWSSRSWIIYGGLVMPGAVLSALLIAALVLGERMIVHPLEQPPLKVAAQARQWTWSFAYPDSRRATLSVNVLHIPAGE
PVDVIVTTKDVIHSFWVPRLGGKIDAIPGHRNVVRLQADRPGVYGGVCAEFCGAGHSAMRFTVLAHEPEEFATIMAGAIE
EARR

Sequences:

>Translated_244_residues
MDWPGGGPVTVAARLRRRPLAGLASLTILSGCTGPLSALDPAGPAAASTATLWWIMFSGAAVLSLLMAALIALAFLKPGI
ASMWSSRSWIIYGGLVMPGAVLSALLIAALVLGERMIVHPLEQPPLKVAAQARQWTWSFAYPDSRRATLSVNVLHIPAGE
PVDVIVTTKDVIHSFWVPRLGGKIDAIPGHRNVVRLQADRPGVYGGVCAEFCGAGHSAMRFTVLAHEPEEFATIMAGAIE
EARR
>Mature_244_residues
MDWPGGGPVTVAARLRRRPLAGLASLTILSGCTGPLSALDPAGPAAASTATLWWIMFSGAAVLSLLMAALIALAFLKPGI
ASMWSSRSWIIYGGLVMPGAVLSALLIAALVLGERMIVHPLEQPPLKVAAQARQWTWSFAYPDSRRATLSVNVLHIPAGE
PVDVIVTTKDVIHSFWVPRLGGKIDAIPGHRNVVRLQADRPGVYGGVCAEFCGAGHSAMRFTVLAHEPEEFATIMAGAIE
EARR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=143, Percent_Identity=33.5664335664336, Blast_Score=83, Evalue=2e-16,
Organism=Escherichia coli, GI1786635, Length=228, Percent_Identity=30.2631578947368, Blast_Score=88, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6226540, Length=197, Percent_Identity=26.3959390862944, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 25861; Mature: 25861

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWPGGGPVTVAARLRRRPLAGLASLTILSGCTGPLSALDPAGPAAASTATLWWIMFSGA
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AVLSLLMAALIALAFLKPGIASMWSSRSWIIYGGLVMPGAVLSALLIAALVLGERMIVHP
HHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCHHEECC
LEQPPLKVAAQARQWTWSFAYPDSRRATLSVNVLHIPAGEPVDVIVTTKDVIHSFWVPRL
CCCCCHHHHHHHHHEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHC
GGKIDAIPGHRNVVRLQADRPGVYGGVCAEFCGAGHSAMRFTVLAHEPEEFATIMAGAIE
CCEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHH
EARR
HHCC
>Mature Secondary Structure
MDWPGGGPVTVAARLRRRPLAGLASLTILSGCTGPLSALDPAGPAAASTATLWWIMFSGA
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AVLSLLMAALIALAFLKPGIASMWSSRSWIIYGGLVMPGAVLSALLIAALVLGERMIVHP
HHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCHHEECC
LEQPPLKVAAQARQWTWSFAYPDSRRATLSVNVLHIPAGEPVDVIVTTKDVIHSFWVPRL
CCCCCHHHHHHHHHEEEEECCCCCCCEEEEEEEEEECCCCCEEEEEECHHHHHHHHHHHC
GGKIDAIPGHRNVVRLQADRPGVYGGVCAEFCGAGHSAMRFTVLAHEPEEFATIMAGAIE
CCEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHH
EARR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]