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The map label for this gene is fecR [H]

Identifier: 75676160

GI number: 75676160

Start: 2157520

End: 2158653

Strand: Direct

Name: fecR [H]

Synonym: Nwi_1969

Alternate gene names: 75676160

Gene position: 2157520-2158653 (Clockwise)

Preceding gene: 75676159

Following gene: 75676162

Centisome position: 63.42

GC content: 63.32

Gene sequence:

>1134_bases
ATGGAACAGAATGGCACGCAGTCAGTCGACGACCAGGCTGTCCAATGGTTCGTTCTGTTGCGCGACGAAGACGCGACAGC
GGAAGATCGGCGCGCATTCGCGCACTGGCTTGCGTTTGACCAGACACATGAAACCGCGTGGCAATCGGTCGAACGGATGT
GGGGTGGCCTCGACGCATTGGCGCCGGAGGTGGTCAGGCAACGGCGCAAACCTCGAAGAAACAGCCGGTTAAAGAGAGGC
GCCGCCGTGGCCCTTTTGCTCGCTGCGATCGGCATCGGCTGGCAGATGGCTCCAACAGGGCTATTCGCCGATTACCGGAC
GGCGATCGGCGAACGCCGGATGATCGTGCTGCAAGACGGCTCCCAGGTCGACCTCGGCGCGGCAAGCGCGCTTGATGTGT
CATTCGGCACGGGCGAACGCAGGGTCAGGCTGCTGACCGGCGAGGCATTCTTCACCGTAACGAAGGACGCCGCCCGGCCA
TTCATCGTGGCGGCCGAGAACGGCGAGGTGAAGGTGCTGGGTACGGCGTTCGACGTCAAGATCGCCGACGGGGTCGCGGT
GGCGGTCGCGCATAACGCGGTCCAAGTTTCTGCTCAAGCCTCCACTCAAGCCCCGGACCGCCCCGATGTCGTCCCGGACG
CTCCGGTCGTTGTCAGACAAGGCCAGATCGTTCGCTACGATTTCGCCGGCATTTCCGCCGTCGGTGCGGCGGACCTGGAG
TCCATTCAAGCGTGGCGGCACGGCCAGCTCGTTTTCCGCGACGTCCCGCTCGATACCGTGCTCACCGAGCTTCAGCGCTA
CCGTTTTGGCCGCATTGTTCTGATCGGCGGAACGTTGGGCCAGCGGCGAGTCACCGCAGTGTTCGATGCAGCCAAGACGG
AGCAGGCCCTCGATACGATCGCCGAATCCCTGTCGCTGCGCATCTATCGAGCCGCCGGCCTGCTGACTGTCATCATTCCG
AACGACAGCGCCGAAAAACTCCCACGGGCGACTAACTACTTTTCCCGATCCTGTCGTCTTCAGAATAGGGATGGGATCGC
GCCGTCGTGGCCGATCCCCTGCCCGCATGTTGAGGACGGGGGACGTCCAATTACGAGGTGGGCGTCAAGGGCGAACTGCT
GGACAAGCGCCTGA

Upstream 100 bases:

>100_bases
CACAATAGCGTCTTAGTCTTATAAGCTGATCAACCTTCGGACTCCGATACGGGACCAAACGATCGGCCAGATCCAGATCA
CAGCCTGCTCCGGGGATTGT

Downstream 100 bases:

>100_bases
ATGTGTCGGCCGCCCTGTTCCGCCTGGACCAGACCAATCTAGCGCGGCCGGACAATTCCGTCCTTCCCGACCCCAGCAAT
GCCTGCGGCGGGGTCTGCTA

Product: FecR protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MEQNGTQSVDDQAVQWFVLLRDEDATAEDRRAFAHWLAFDQTHETAWQSVERMWGGLDALAPEVVRQRRKPRRNSRLKRG
AAVALLLAAIGIGWQMAPTGLFADYRTAIGERRMIVLQDGSQVDLGAASALDVSFGTGERRVRLLTGEAFFTVTKDAARP
FIVAAENGEVKVLGTAFDVKIADGVAVAVAHNAVQVSAQASTQAPDRPDVVPDAPVVVRQGQIVRYDFAGISAVGAADLE
SIQAWRHGQLVFRDVPLDTVLTELQRYRFGRIVLIGGTLGQRRVTAVFDAAKTEQALDTIAESLSLRIYRAAGLLTVIIP
NDSAEKLPRATNYFSRSCRLQNRDGIAPSWPIPCPHVEDGGRPITRWASRANCWTSA

Sequences:

>Translated_377_residues
MEQNGTQSVDDQAVQWFVLLRDEDATAEDRRAFAHWLAFDQTHETAWQSVERMWGGLDALAPEVVRQRRKPRRNSRLKRG
AAVALLLAAIGIGWQMAPTGLFADYRTAIGERRMIVLQDGSQVDLGAASALDVSFGTGERRVRLLTGEAFFTVTKDAARP
FIVAAENGEVKVLGTAFDVKIADGVAVAVAHNAVQVSAQASTQAPDRPDVVPDAPVVVRQGQIVRYDFAGISAVGAADLE
SIQAWRHGQLVFRDVPLDTVLTELQRYRFGRIVLIGGTLGQRRVTAVFDAAKTEQALDTIAESLSLRIYRAAGLLTVIIP
NDSAEKLPRATNYFSRSCRLQNRDGIAPSWPIPCPHVEDGGRPITRWASRANCWTSA
>Mature_377_residues
MEQNGTQSVDDQAVQWFVLLRDEDATAEDRRAFAHWLAFDQTHETAWQSVERMWGGLDALAPEVVRQRRKPRRNSRLKRG
AAVALLLAAIGIGWQMAPTGLFADYRTAIGERRMIVLQDGSQVDLGAASALDVSFGTGERRVRLLTGEAFFTVTKDAARP
FIVAAENGEVKVLGTAFDVKIADGVAVAVAHNAVQVSAQASTQAPDRPDVVPDAPVVVRQGQIVRYDFAGISAVGAADLE
SIQAWRHGQLVFRDVPLDTVLTELQRYRFGRIVLIGGTLGQRRVTAVFDAAKTEQALDTIAESLSLRIYRAAGLLTVIIP
NDSAEKLPRATNYFSRSCRLQNRDGIAPSWPIPCPHVEDGGRPITRWASRANCWTSA

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=304, Percent_Identity=31.25, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 41268; Mature: 41268

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNGTQSVDDQAVQWFVLLRDEDATAEDRRAFAHWLAFDQTHETAWQSVERMWGGLDAL
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
APEVVRQRRKPRRNSRLKRGAAVALLLAAIGIGWQMAPTGLFADYRTAIGERRMIVLQDG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEEEEECC
SQVDLGAASALDVSFGTGERRVRLLTGEAFFTVTKDAARPFIVAAENGEVKVLGTAFDVK
CEECCCCCCEEEEEECCCCCEEEEEECCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEE
IADGVAVAVAHNAVQVSAQASTQAPDRPDVVPDAPVVVRQGQIVRYDFAGISAVGAADLE
ECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHHH
SIQAWRHGQLVFRDVPLDTVLTELQRYRFGRIVLIGGTLGQRRVTAVFDAAKTEQALDTI
HHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AESLSLRIYRAAGLLTVIIPNDSAEKLPRATNYFSRSCRLQNRDGIAPSWPIPCPHVEDG
HHHHHEEEEEECCEEEEEECCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GRPITRWASRANCWTSA
CCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEQNGTQSVDDQAVQWFVLLRDEDATAEDRRAFAHWLAFDQTHETAWQSVERMWGGLDAL
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHH
APEVVRQRRKPRRNSRLKRGAAVALLLAAIGIGWQMAPTGLFADYRTAIGERRMIVLQDG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEEEEECC
SQVDLGAASALDVSFGTGERRVRLLTGEAFFTVTKDAARPFIVAAENGEVKVLGTAFDVK
CEECCCCCCEEEEEECCCCCEEEEEECCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEE
IADGVAVAVAHNAVQVSAQASTQAPDRPDVVPDAPVVVRQGQIVRYDFAGISAVGAADLE
ECCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHHH
SIQAWRHGQLVFRDVPLDTVLTELQRYRFGRIVLIGGTLGQRRVTAVFDAAKTEQALDTI
HHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
AESLSLRIYRAAGLLTVIIPNDSAEKLPRATNYFSRSCRLQNRDGIAPSWPIPCPHVEDG
HHHHHEEEEEECCEEEEEECCCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GRPITRWASRANCWTSA
CCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]