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The map label for this gene is pdtaS [H]

Identifier: 75675948

GI number: 75675948

Start: 1925655

End: 1926743

Strand: Direct

Name: pdtaS [H]

Synonym: Nwi_1756

Alternate gene names: 75675948

Gene position: 1925655-1926743 (Clockwise)

Preceding gene: 75675947

Following gene: 75675949

Centisome position: 56.6

GC content: 62.99

Gene sequence:

>1089_bases
ATGAACGTCAAGCCTACCCTTTTGTATGTGGATGACGACAAGGCGCTGGCTCGTCTGGTGGAGCGCGGCCTGACACGTCA
CGGATTTTGCGTGGAGTACGCATCCGACGGCGAGGCCGGACTCGCACGCATCGCGCAGGGCGGCATCGATGTGATAGCGC
TCGACCAATACATGCCCGGCCTGGACGGGCTGGAGACGCTAGGCCGGATTCAGGCAATTCCCAACGCGCCCCCCGTGGTT
TTCGTCACCGCTTCGCAAAACTCAAAGATCGCAGTCACCGCGCTCAAGGCCGGGGCCGCGGATTATCTTGTCAAGGACAC
GCTCGGTGAGTTCGTTCCGCTGTTGCACGTCGCGGCCGAAGTGGCGATCCGCCAGGCGCTCGTTCAAAAGGCACGCGACG
AGGCTGAAGCCGAAGTCCGCGCCTCACGCGATCGCTATGCGGCGCTGGCCGCCGAGCGCGAGATGCTGCTGCGCGAGGTC
AATCATCGCATCGGCAACAGTCTCCAGATCATCGCGTCACTGCTGCATCTGCAAGCCAATTCGAGCCCCGAGGAAGACAT
CAAGGCCGCCCTCACCAATGCAATGGGACGGGTGGCGGCAGTCGCGCAGGTGCATCGCCGGCTCTACACGTCGCACGACC
TGAAGAGCGTCCTGCTGAACCAGTATCTTGAAGCACTGCTCGAGGATCTCCGGCGCTCCACCGAAGGCAACCGGATGTCG
CGCCTCGACCTGAAAGCCCAGCCCGTCGAGATCGATCCCGATCGCGCCGTCGCCATCGGGATCATCGTCAATGAACTGGT
GATGAATGCGGTCAAGTACGCCTATCCTGATGGCCCCGGCCCCATCCACGTCGAACTCGCGTCCGACGGCGATGATATCG
TGCTGTCAATCACTGACGATGGCGTCGGCCTCAATGCAAGAAGCGATCCGCGCTCGACCGGAATGGGCCAGCGGATTGTT
TCAGCGATGGCGCAGAAGCTCGACGCGCAGGCCGAACGCGATCCCACCCACGCGGGCACGCGCATCGTTCTGCGGTTCCG
GAGCGGAACTCCTCAGGTCGCGAAACCCATGTCCGCGACCGCGGCATGA

Upstream 100 bases:

>100_bases
GCGTCTACATCACAAAGCCAGTGAACTATGACAATTTCGCCAATGCGATCCGGCAACTCGGTCTGTTTTTCTCCATCATT
CAGGTACCTCAGGCTACTCC

Downstream 100 bases:

>100_bases
GCACGGCGGCAGCAAGCTGAAAGCGCCTTCGCGCCTGACATGACATCAGGTCGAGGCCCAACACTCAATTCGTGATGATG
GAACCAGAAGCGAACCGACA

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNVKPTLLYVDDDKALARLVERGLTRHGFCVEYASDGEAGLARIAQGGIDVIALDQYMPGLDGLETLGRIQAIPNAPPVV
FVTASQNSKIAVTALKAGAADYLVKDTLGEFVPLLHVAAEVAIRQALVQKARDEAEAEVRASRDRYAALAAEREMLLREV
NHRIGNSLQIIASLLHLQANSSPEEDIKAALTNAMGRVAAVAQVHRRLYTSHDLKSVLLNQYLEALLEDLRRSTEGNRMS
RLDLKAQPVEIDPDRAVAIGIIVNELVMNAVKYAYPDGPGPIHVELASDGDDIVLSITDDGVGLNARSDPRSTGMGQRIV
SAMAQKLDAQAERDPTHAGTRIVLRFRSGTPQVAKPMSATAA

Sequences:

>Translated_362_residues
MNVKPTLLYVDDDKALARLVERGLTRHGFCVEYASDGEAGLARIAQGGIDVIALDQYMPGLDGLETLGRIQAIPNAPPVV
FVTASQNSKIAVTALKAGAADYLVKDTLGEFVPLLHVAAEVAIRQALVQKARDEAEAEVRASRDRYAALAAEREMLLREV
NHRIGNSLQIIASLLHLQANSSPEEDIKAALTNAMGRVAAVAQVHRRLYTSHDLKSVLLNQYLEALLEDLRRSTEGNRMS
RLDLKAQPVEIDPDRAVAIGIIVNELVMNAVKYAYPDGPGPIHVELASDGDDIVLSITDDGVGLNARSDPRSTGMGQRIV
SAMAQKLDAQAERDPTHAGTRIVLRFRSGTPQVAKPMSATAA
>Mature_362_residues
MNVKPTLLYVDDDKALARLVERGLTRHGFCVEYASDGEAGLARIAQGGIDVIALDQYMPGLDGLETLGRIQAIPNAPPVV
FVTASQNSKIAVTALKAGAADYLVKDTLGEFVPLLHVAAEVAIRQALVQKARDEAEAEVRASRDRYAALAAEREMLLREV
NHRIGNSLQIIASLLHLQANSSPEEDIKAALTNAMGRVAAVAQVHRRLYTSHDLKSVLLNQYLEALLEDLRRSTEGNRMS
RLDLKAQPVEIDPDRAVAIGIIVNELVMNAVKYAYPDGPGPIHVELASDGDDIVLSITDDGVGLNARSDPRSTGMGQRIV
SAMAQKLDAQAERDPTHAGTRIVLRFRSGTPQVAKPMSATAA

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=99, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39016; Mature: 39016

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKPTLLYVDDDKALARLVERGLTRHGFCVEYASDGEAGLARIAQGGIDVIALDQYMPG
CCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCCC
LDGLETLGRIQAIPNAPPVVFVTASQNSKIAVTALKAGAADYLVKDTLGEFVPLLHVAAE
CHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VAIRQALVQKARDEAEAEVRASRDRYAALAAEREMLLREVNHRIGNSLQIIASLLHLQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
SSPEEDIKAALTNAMGRVAAVAQVHRRLYTSHDLKSVLLNQYLEALLEDLRRSTEGNRMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RLDLKAQPVEIDPDRAVAIGIIVNELVMNAVKYAYPDGPGPIHVELASDGDDIVLSITDD
ECCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECC
GVGLNARSDPRSTGMGQRIVSAMAQKLDAQAERDPTHAGTRIVLRFRSGTPQVAKPMSAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCCCHHC
AA
CC
>Mature Secondary Structure
MNVKPTLLYVDDDKALARLVERGLTRHGFCVEYASDGEAGLARIAQGGIDVIALDQYMPG
CCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCCC
LDGLETLGRIQAIPNAPPVVFVTASQNSKIAVTALKAGAADYLVKDTLGEFVPLLHVAAE
CHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
VAIRQALVQKARDEAEAEVRASRDRYAALAAEREMLLREVNHRIGNSLQIIASLLHLQAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
SSPEEDIKAALTNAMGRVAAVAQVHRRLYTSHDLKSVLLNQYLEALLEDLRRSTEGNRMS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
RLDLKAQPVEIDPDRAVAIGIIVNELVMNAVKYAYPDGPGPIHVELASDGDDIVLSITDD
ECCCCCCCCEECCCCCEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECC
GVGLNARSDPRSTGMGQRIVSAMAQKLDAQAERDPTHAGTRIVLRFRSGTPQVAKPMSAT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHCCCHHC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]