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The map label for this gene is fabA [H]

Identifier: 75675770

GI number: 75675770

Start: 1725674

End: 1726216

Strand: Direct

Name: fabA [H]

Synonym: Nwi_1578

Alternate gene names: 75675770

Gene position: 1725674-1726216 (Clockwise)

Preceding gene: 75675769

Following gene: 75675771

Centisome position: 50.72

GC content: 58.2

Gene sequence:

>543_bases
ATGCCTAACCTTCGCAGCAGCTATGATTACGAGGACTTGCTGGCTTGCGGCCGTGGCGAGATGTTCGGCCCCGGCGAACC
CAAACTTCCGTTGCCGCCGATGCTGATGTTCGATCGCATCACGGAGATTACCGAAGGCGGCGGGAAATATGGACGCGGCC
TGGTGCGCACCGAGCTCGACATCAAACCGAACCTCTGGTTCTTCCAATGCCATTTTCAGAACGACCCGGTGATGCCCGGC
TGTCTCGGTCTCGACGGGCTTTGGCAGATGGTGGGATTCTATCTGGTCTGGCTTGGCCGCGACCGGAATGTGCGGGCTCG
TGCGCTCGGTCTTGGTGACTTGAAGTTTACAGGTCAAATCTTGCCGCACGCCCGCAAGATATCCTACACGGTCGATATCA
AGCGGGTGATGCGTTCGAAGCTGGTGATGGCGATTGCCGACGGTACAGTCAGCGTCGACGGCGATACGATTTATCATGCC
AAGGATCTTCGGCTCGGCCTGTTCAAGAGCCTGCCCGGATCACCGATTGAGCCGACAAGCTGA

Upstream 100 bases:

>100_bases
TAATTATACCGCTGTTGCTATCTCGGGTAGCGGCAAGAGTTCCACCCCTCAGCTTCACGGTTTCCTTTCCTTCGTCGCTT
CAGCGGGGATCAGGGTCGAA

Downstream 100 bases:

>100_bases
TAAGCTCCCGGCTATTGAGTCGGCTTGAGCTTGTACCGTGGAAACCTCGCTTTATCTTCCGGTCAAACGCCATCTTGAAA
GCCTTGGTTTCTCGGTCAAA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPNLRSSYDYEDLLACGRGEMFGPGEPKLPLPPMLMFDRITEITEGGGKYGRGLVRTELDIKPNLWFFQCHFQNDPVMPG
CLGLDGLWQMVGFYLVWLGRDRNVRARALGLGDLKFTGQILPHARKISYTVDIKRVMRSKLVMAIADGTVSVDGDTIYHA
KDLRLGLFKSLPGSPIEPTS

Sequences:

>Translated_180_residues
MPNLRSSYDYEDLLACGRGEMFGPGEPKLPLPPMLMFDRITEITEGGGKYGRGLVRTELDIKPNLWFFQCHFQNDPVMPG
CLGLDGLWQMVGFYLVWLGRDRNVRARALGLGDLKFTGQILPHARKISYTVDIKRVMRSKLVMAIADGTVSVDGDTIYHA
KDLRLGLFKSLPGSPIEPTS
>Mature_179_residues
PNLRSSYDYEDLLACGRGEMFGPGEPKLPLPPMLMFDRITEITEGGGKYGRGLVRTELDIKPNLWFFQCHFQNDPVMPGC
LGLDGLWQMVGFYLVWLGRDRNVRARALGLGDLKFTGQILPHARKISYTVDIKRVMRSKLVMAIADGTVSVDGDTIYHAK
DLRLGLFKSLPGSPIEPTS

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=169, Percent_Identity=57.396449704142, Blast_Score=208, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 20133; Mature: 20002

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNLRSSYDYEDLLACGRGEMFGPGEPKLPLPPMLMFDRITEITEGGGKYGRGLVRTELD
CCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEC
IKPNLWFFQCHFQNDPVMPGCLGLDGLWQMVGFYLVWLGRDRNVRARALGLGDLKFTGQI
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCEECCCC
LPHARKISYTVDIKRVMRSKLVMAIADGTVSVDGDTIYHAKDLRLGLFKSLPGSPIEPTS
CCCCEEEEEEEHHHHHHHHHEEEEEECCEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PNLRSSYDYEDLLACGRGEMFGPGEPKLPLPPMLMFDRITEITEGGGKYGRGLVRTELD
CCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEC
IKPNLWFFQCHFQNDPVMPGCLGLDGLWQMVGFYLVWLGRDRNVRARALGLGDLKFTGQI
CCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCEEEEEECCCCEECCCC
LPHARKISYTVDIKRVMRSKLVMAIADGTVSVDGDTIYHAKDLRLGLFKSLPGSPIEPTS
CCCCEEEEEEEHHHHHHHHHEEEEEECCEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA