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The map label for this gene is recG [H]

Identifier: 75675707

GI number: 75675707

Start: 1647153

End: 1649252

Strand: Direct

Name: recG [H]

Synonym: Nwi_1515

Alternate gene names: 75675707

Gene position: 1647153-1649252 (Clockwise)

Preceding gene: 75675704

Following gene: 75675710

Centisome position: 48.42

GC content: 66.19

Gene sequence:

>2100_bases
ATGCGTCCCGCGCTGCTCAATCCGCTCTTTGTACCGGTGACCAGCCTGTCCGGCGTCGGACCGAAGCAGGACAGGCTGTT
CCGGCACCTGCTCGCGCGCGATGAAACGCCGCGGCTGGTTGATCTGCTGTTTCACCTGCCTGCAAGCGTCGTCGATCGCA
GGGCGCGACCCAAAATCCGTGACGCCGTCCCCGGCACGATCGTGACGCTGGAGGTGAGCGTCGACCGGCATCGCCCGGCG
CCGCCCGGACGCTCGCGCGCGCCGCATCTCGTCTATGCCAGCGACGAAACCGGAAGCGTCGTCCTGACCTACTTCCGCGC
TCAGCCGAGCTATGTCGAAAAACTGCTTCCCGCAGGCAGCAAGCGTTATGTGTCCGGCACGGTGCAGATGTTCGACGGCA
CGCTGCAGATCGTGCATCCCGACCGGGTTGTCGATGAAGCCGGGCTGGCGGAGCTTTCCGGCATCGATCCCGTCTATCCC
CTCACCCAGGGTCTGGCGCCGGGGGCGTTGCGCCGCGCGATCGCGCAGGCATTGCAGAATCTGCCCGTGTTGCCCGAATG
GACCGATCCGAAGATTTTACGTCGCTGTGGCTTTCCGCCGCTGGCTCAGGCGCTCCGCCGGGTCCACGTCCCCCTGGAGT
TGACTGATACGCTGCCGGAAGGCCCGTTCTGGTCACGCCTCGCCTTCGACGAACTGCTGGCCGGCCAGCTTGCGCTAACG
CTGGTGCGCGCGCGGCTTCGCCGCCCGGCTGGAAACCGGCACGCGGGCGACGGACACCTGCGCAACAGGATTATCGATGC
GCTCCCCTACGCCCTCACCGCATCCCAACAGCAAGCCGTCGCGGCGATCATCGAAGACCTGCGGCAGCCGGTGAGGATGC
TGCGGCTGCTTCAGGGCGATGTCGGCTCGGGCAAGACCGTGGTCGCGCTGCTGGCCGCCTGCGCGGTGGCCGAATCCGGC
AAGCAGACGGCCTTGATGGCGCCGACCGAGGTTCTTGCTCGCCAGCATATCAAGACCATCGCGCCGCTGGCCGAACGGGC
CGGCCTGCGGGTTGCGATTCTGACCGGCCGCGAGAAAGGCAGGGAACGGCGCGAGATCACGGCGCGCCTCGCCGAAGGCG
ACATTGACCTGCTTGTAGGCACCCATGCGTTGATCCAGGATGAGGTCACGTTCAAATCGCTGGCGCTCGCGGTGGTGGAT
GAGCAGCACCGTTTCGGCGTGCGCGAGCGCCTCGCGCTGACGACGAAGGGTGAAGCTGTCGATGTCCTGGTGCTGAGCGC
GACGCCGATCCCGCGCACGCTGGTGCTGACCTATTTCGGCGACATGGATGTCTCCGAATTGCGCGACAAGCCCGCGGGCC
GGCAGCCGATCGATACCCGCGCCGTTTCCGACGGCCGGTTGACCGAGGTCATCGACGCCGTTGGCCGCGCCGTGAAGGCG
GGAAAGCTGGCTTACTGGATCTGTCCGCTGGTTGAGGAATCCGACGCCGTCGACCTGAGCGATGCCGAGCAGCGCTACCA
AAGCCTCAAGGCTCGCTTCGGCGACAGGGTCGGCCTTGTTCACGGCAAGATGCGCGGCCCCGAAAAGGATCGCGTGATGG
CGCAATTCGCGGCCGGCGAAATCAATCTGCTGGTCGCGACAACCGTCGTCGAGGTCGGCGTCGACGTTCCGGCGGCGACG
ATCATGGTGATCGAGAACGCCGAACGCTTCGGTCTGGCGCAACTCCATCAGTTACGAGGCCGGATCGGTCGTGGTTCGGA
GCCCTCCACGTGCCTGCTGCTTTACCGGGAGCCTTTGGGCGAGATGTCAGCCGCCCGGCTGCGGGTGATCCGGGAGACCA
CGGACGGATTCCGCATTGCCGAAGAAGACCTGAGGCTGCGCGGCGAAGGCGATGTGCTCGGCACGCGTCAAAGCGGCCTG
CCCGGCTATCGCGTCGCGCGCTCGGATGTCCATGCGCAACTCATCACGCTGGCCCGCGACGAAGCCCTGCGCATTCTGAA
GCAGAATCCGAATCTCACGGGCTCGCACGGCGAAGCCTTGCGATGCCTGCTGTATCTGTTTGAGCGCGACGAAGCCCTGC
CCCTGCTCGGCGCGGGTTAA

Upstream 100 bases:

>100_bases
CCGGAATAATGGATGTCAGCATCCGTTTCGCGCATTGCGCAATCAGAGATTTGCATTCAAGGCTTGCAGTTGGTCCAGAT
CATTCCGCCCGAGTCCTGAG

Downstream 100 bases:

>100_bases
AAGCGAGGCATGTCTCCGGGCTGGCCCCCGAGCATGAAAGACCTATTCGCGTGAAGAAAACGCTACAGGTCGAGGTCTGG
ACAGCCTCCGCTCCTCACCC

Product: DEAD/DEAH box helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MRPALLNPLFVPVTSLSGVGPKQDRLFRHLLARDETPRLVDLLFHLPASVVDRRARPKIRDAVPGTIVTLEVSVDRHRPA
PPGRSRAPHLVYASDETGSVVLTYFRAQPSYVEKLLPAGSKRYVSGTVQMFDGTLQIVHPDRVVDEAGLAELSGIDPVYP
LTQGLAPGALRRAIAQALQNLPVLPEWTDPKILRRCGFPPLAQALRRVHVPLELTDTLPEGPFWSRLAFDELLAGQLALT
LVRARLRRPAGNRHAGDGHLRNRIIDALPYALTASQQQAVAAIIEDLRQPVRMLRLLQGDVGSGKTVVALLAACAVAESG
KQTALMAPTEVLARQHIKTIAPLAERAGLRVAILTGREKGRERREITARLAEGDIDLLVGTHALIQDEVTFKSLALAVVD
EQHRFGVRERLALTTKGEAVDVLVLSATPIPRTLVLTYFGDMDVSELRDKPAGRQPIDTRAVSDGRLTEVIDAVGRAVKA
GKLAYWICPLVEESDAVDLSDAEQRYQSLKARFGDRVGLVHGKMRGPEKDRVMAQFAAGEINLLVATTVVEVGVDVPAAT
IMVIENAERFGLAQLHQLRGRIGRGSEPSTCLLLYREPLGEMSAARLRVIRETTDGFRIAEEDLRLRGEGDVLGTRQSGL
PGYRVARSDVHAQLITLARDEALRILKQNPNLTGSHGEALRCLLYLFERDEALPLLGAG

Sequences:

>Translated_699_residues
MRPALLNPLFVPVTSLSGVGPKQDRLFRHLLARDETPRLVDLLFHLPASVVDRRARPKIRDAVPGTIVTLEVSVDRHRPA
PPGRSRAPHLVYASDETGSVVLTYFRAQPSYVEKLLPAGSKRYVSGTVQMFDGTLQIVHPDRVVDEAGLAELSGIDPVYP
LTQGLAPGALRRAIAQALQNLPVLPEWTDPKILRRCGFPPLAQALRRVHVPLELTDTLPEGPFWSRLAFDELLAGQLALT
LVRARLRRPAGNRHAGDGHLRNRIIDALPYALTASQQQAVAAIIEDLRQPVRMLRLLQGDVGSGKTVVALLAACAVAESG
KQTALMAPTEVLARQHIKTIAPLAERAGLRVAILTGREKGRERREITARLAEGDIDLLVGTHALIQDEVTFKSLALAVVD
EQHRFGVRERLALTTKGEAVDVLVLSATPIPRTLVLTYFGDMDVSELRDKPAGRQPIDTRAVSDGRLTEVIDAVGRAVKA
GKLAYWICPLVEESDAVDLSDAEQRYQSLKARFGDRVGLVHGKMRGPEKDRVMAQFAAGEINLLVATTVVEVGVDVPAAT
IMVIENAERFGLAQLHQLRGRIGRGSEPSTCLLLYREPLGEMSAARLRVIRETTDGFRIAEEDLRLRGEGDVLGTRQSGL
PGYRVARSDVHAQLITLARDEALRILKQNPNLTGSHGEALRCLLYLFERDEALPLLGAG
>Mature_699_residues
MRPALLNPLFVPVTSLSGVGPKQDRLFRHLLARDETPRLVDLLFHLPASVVDRRARPKIRDAVPGTIVTLEVSVDRHRPA
PPGRSRAPHLVYASDETGSVVLTYFRAQPSYVEKLLPAGSKRYVSGTVQMFDGTLQIVHPDRVVDEAGLAELSGIDPVYP
LTQGLAPGALRRAIAQALQNLPVLPEWTDPKILRRCGFPPLAQALRRVHVPLELTDTLPEGPFWSRLAFDELLAGQLALT
LVRARLRRPAGNRHAGDGHLRNRIIDALPYALTASQQQAVAAIIEDLRQPVRMLRLLQGDVGSGKTVVALLAACAVAESG
KQTALMAPTEVLARQHIKTIAPLAERAGLRVAILTGREKGRERREITARLAEGDIDLLVGTHALIQDEVTFKSLALAVVD
EQHRFGVRERLALTTKGEAVDVLVLSATPIPRTLVLTYFGDMDVSELRDKPAGRQPIDTRAVSDGRLTEVIDAVGRAVKA
GKLAYWICPLVEESDAVDLSDAEQRYQSLKARFGDRVGLVHGKMRGPEKDRVMAQFAAGEINLLVATTVVEVGVDVPAAT
IMVIENAERFGLAQLHQLRGRIGRGSEPSTCLLLYREPLGEMSAARLRVIRETTDGFRIAEEDLRLRGEGDVLGTRQSGL
PGYRVARSDVHAQLITLARDEALRILKQNPNLTGSHGEALRCLLYLFERDEALPLLGAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=650, Percent_Identity=41.3846153846154, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1787357, Length=381, Percent_Identity=39.1076115485564, Blast_Score=254, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76425; Mature: 76425

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPALLNPLFVPVTSLSGVGPKQDRLFRHLLARDETPRLVDLLFHLPASVVDRRARPKIR
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCHH
DAVPGTIVTLEVSVDRHRPAPPGRSRAPHLVYASDETGSVVLTYFRAQPSYVEKLLPAGS
HCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHCCCCC
KRYVSGTVQMFDGTLQIVHPDRVVDEAGLAELSGIDPVYPLTQGLAPGALRRAIAQALQN
CEEHHHEEEEECCEEEEECCHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHC
LPVLPEWTDPKILRRCGFPPLAQALRRVHVPLELTDTLPEGPFWSRLAFDELLAGQLALT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVRARLRRPAGNRHAGDGHLRNRIIDALPYALTASQQQAVAAIIEDLRQPVRMLRLLQGD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VGSGKTVVALLAACAVAESGKQTALMAPTEVLARQHIKTIAPLAERAGLRVAILTGREKG
CCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
RERREITARLAEGDIDLLVGTHALIQDEVTFKSLALAVVDEQHRFGVRERLALTTKGEAV
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHEEEECCCEE
DVLVLSATPIPRTLVLTYFGDMDVSELRDKPAGRQPIDTRAVSDGRLTEVIDAVGRAVKA
EEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GKLAYWICPLVEESDAVDLSDAEQRYQSLKARFGDRVGLVHGKMRGPEKDRVMAQFAAGE
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCC
INLLVATTVVEVGVDVPAATIMVIENAERFGLAQLHQLRGRIGRGSEPSTCLLLYREPLG
EEEEEEHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
EMSAARLRVIRETTDGFRIAEEDLRLRGEGDVLGTRQSGLPGYRVARSDVHAQLITLARD
HHHHHHHHHHHHCCCCCEEEHHHHEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHH
EALRILKQNPNLTGSHGEALRCLLYLFERDEALPLLGAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRPALLNPLFVPVTSLSGVGPKQDRLFRHLLARDETPRLVDLLFHLPASVVDRRARPKIR
CCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCCCCCHH
DAVPGTIVTLEVSVDRHRPAPPGRSRAPHLVYASDETGSVVLTYFRAQPSYVEKLLPAGS
HCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCHHHHHHHCCCCC
KRYVSGTVQMFDGTLQIVHPDRVVDEAGLAELSGIDPVYPLTQGLAPGALRRAIAQALQN
CEEHHHEEEEECCEEEEECCHHHHHHCCCHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHC
LPVLPEWTDPKILRRCGFPPLAQALRRVHVPLELTDTLPEGPFWSRLAFDELLAGQLALT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LVRARLRRPAGNRHAGDGHLRNRIIDALPYALTASQQQAVAAIIEDLRQPVRMLRLLQGD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
VGSGKTVVALLAACAVAESGKQTALMAPTEVLARQHIKTIAPLAERAGLRVAILTGREKG
CCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
RERREITARLAEGDIDLLVGTHALIQDEVTFKSLALAVVDEQHRFGVRERLALTTKGEAV
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHEEEECCCEE
DVLVLSATPIPRTLVLTYFGDMDVSELRDKPAGRQPIDTRAVSDGRLTEVIDAVGRAVKA
EEEEEECCCCCCEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GKLAYWICPLVEESDAVDLSDAEQRYQSLKARFGDRVGLVHGKMRGPEKDRVMAQFAAGE
CCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCC
INLLVATTVVEVGVDVPAATIMVIENAERFGLAQLHQLRGRIGRGSEPSTCLLLYREPLG
EEEEEEHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
EMSAARLRVIRETTDGFRIAEEDLRLRGEGDVLGTRQSGLPGYRVARSDVHAQLITLARD
HHHHHHHHHHHHCCCCCEEEHHHHEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHH
EALRILKQNPNLTGSHGEALRCLLYLFERDEALPLLGAG
HHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]