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The map label for this gene is visC [C]

Identifier: 75675699

GI number: 75675699

Start: 1635569

End: 1636843

Strand: Direct

Name: visC [C]

Synonym: Nwi_1507

Alternate gene names: 75675699

Gene position: 1635569-1636843 (Clockwise)

Preceding gene: 75675695

Following gene: 75675700

Centisome position: 48.08

GC content: 65.18

Gene sequence:

>1275_bases
ATGAACGAGAGCGCGAAGCCGGTTGCAATCTTTGATGTCGCGGTGGTGGGCGGAGGGCCTGCCGGATTGGCTGCGGCGAT
CGCCCTCTCCCATGCCGGCGCGCGGACGGCGCTAATCGCGCGGCGCGTCGGTTATGGCGATAACCGGACGACAGCCCTGC
TTGGCGGTTCCATCGATCTGTTACGAGAGCTTGACGTATGGCCCCGCTGCGAGGCCGATGCCGCCCCTCTCCGTGTCATG
CGGCTTGTGGACGATACCGGACGTCTTATCCGGGCTCCCGAGGTGCGTTTTTCCGCCGCCGAGATCGGGCGCGACGCATT
CGGCTACAATATTGCAAACCGCGCGCTGATGGCCGCCATGGAGGCGCGCGCCGCGGAAGCGGAAAACCTCACGCGGATCG
ACGGCGAAGCTGAGCAGGTCACGCCCGGCGATACCGTGGTCACCATCACCACCCGGCAGGGAGATGAATTGAGCGCTCGT
CTGGCGGTCGGGGCCGACGGGCGGCAGTCGCTATGCCGCAAAGCCGCGTGCATCGGCATTACGCGTCGCGCGCTCGATCA
GGCTGCTTTGACGTTCAACGTCGCGCATAGCCGGCCGCACAAAAACACCTCGACCGAGTTTCATACCCCGCATGGTCCCT
GCGTTTTTGTGCCGCTGCCCGGAGACCGCTCCAGTGTCGTCTGGGTCGCCTCCCCCAGGGAGGTGGAGCGGCTTGCCGCC
CTGAGCGACGACGAACTGGCCGAAGCCGCCGAACGGAGATCGCATTCGATCCTGGGACGGCTTGAGGTCGGCCAGGGACG
AAATAAGTTTCCGTTAGGGATCGAGCGGCCCGCGCGATTTGCAGGCAACCGCATCGTTCTGGTCGGCGAATCCGCCCATG
TCCTGCCGCCGATCGGCGCGCAGGGGCTGAACCTGGGCCTGCGTGACGCCGCCGATATCGCGGAGATTGTCGGCGACGTT
CTGTCCTCCGGGGAAGATCCCGGCGCATCTCCCGCTCTTGCGCGTTTCGAAACGGCGCGGCGCAGCGACGTTCTGAGCCG
AACCTTCGCGATCGACGTGGCGAACCGGTCGCTGCTCAGCGATTTCCTGCCGATCCAGACCGCACGCGCATTCGGGCTGC
ACCTGATCAGCAAGGTCGGTCCGCTCCGACGCCTTGCCATGCGCGAGGGTCTCGCGCCGTCGTGGCGGCGGCGTCCACAT
AGGGAGCCTCGGTCTAAAGCATTTTCCGGCGAAGTGGATACCGGTTCGTCGCAAGAAAATGCGTCAAAACAATAA

Upstream 100 bases:

>100_bases
GTGCTCCGCCGCGCGAGCAGTCGGGAGCAATGTCATCCGGTTCCGGCAATGTTAGCCGGGCGGGCTTGAAAATGGCGCGG
CGAATGGCGATTGTCGATCC

Downstream 100 bases:

>100_bases
TCTAGAGCCTCGCTTCTGATTCAATCAGAAGCGAACGTGCTCTAGCCAGCCTTGAGCCGAGGCCTCGACTCCCGCCCGTG
GAGTCCAGTCCGATCTCGCC

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNESAKPVAIFDVAVVGGGPAGLAAAIALSHAGARTALIARRVGYGDNRTTALLGGSIDLLRELDVWPRCEADAAPLRVM
RLVDDTGRLIRAPEVRFSAAEIGRDAFGYNIANRALMAAMEARAAEAENLTRIDGEAEQVTPGDTVVTITTRQGDELSAR
LAVGADGRQSLCRKAACIGITRRALDQAALTFNVAHSRPHKNTSTEFHTPHGPCVFVPLPGDRSSVVWVASPREVERLAA
LSDDELAEAAERRSHSILGRLEVGQGRNKFPLGIERPARFAGNRIVLVGESAHVLPPIGAQGLNLGLRDAADIAEIVGDV
LSSGEDPGASPALARFETARRSDVLSRTFAIDVANRSLLSDFLPIQTARAFGLHLISKVGPLRRLAMREGLAPSWRRRPH
REPRSKAFSGEVDTGSSQENASKQ

Sequences:

>Translated_424_residues
MNESAKPVAIFDVAVVGGGPAGLAAAIALSHAGARTALIARRVGYGDNRTTALLGGSIDLLRELDVWPRCEADAAPLRVM
RLVDDTGRLIRAPEVRFSAAEIGRDAFGYNIANRALMAAMEARAAEAENLTRIDGEAEQVTPGDTVVTITTRQGDELSAR
LAVGADGRQSLCRKAACIGITRRALDQAALTFNVAHSRPHKNTSTEFHTPHGPCVFVPLPGDRSSVVWVASPREVERLAA
LSDDELAEAAERRSHSILGRLEVGQGRNKFPLGIERPARFAGNRIVLVGESAHVLPPIGAQGLNLGLRDAADIAEIVGDV
LSSGEDPGASPALARFETARRSDVLSRTFAIDVANRSLLSDFLPIQTARAFGLHLISKVGPLRRLAMREGLAPSWRRRPH
REPRSKAFSGEVDTGSSQENASKQ
>Mature_424_residues
MNESAKPVAIFDVAVVGGGPAGLAAAIALSHAGARTALIARRVGYGDNRTTALLGGSIDLLRELDVWPRCEADAAPLRVM
RLVDDTGRLIRAPEVRFSAAEIGRDAFGYNIANRALMAAMEARAAEAENLTRIDGEAEQVTPGDTVVTITTRQGDELSAR
LAVGADGRQSLCRKAACIGITRRALDQAALTFNVAHSRPHKNTSTEFHTPHGPCVFVPLPGDRSSVVWVASPREVERLAA
LSDDELAEAAERRSHSILGRLEVGQGRNKFPLGIERPARFAGNRIVLVGESAHVLPPIGAQGLNLGLRDAADIAEIVGDV
LSSGEDPGASPALARFETARRSDVLSRTFAIDVANRSLLSDFLPIQTARAFGLHLISKVGPLRRLAMREGLAPSWRRRPH
REPRSKAFSGEVDTGSSQENASKQ

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=406, Percent_Identity=22.9064039408867, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI32967307, Length=275, Percent_Identity=25.0909090909091, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1789273, Length=339, Percent_Identity=30.9734513274336, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1786883, Length=390, Percent_Identity=27.1794871794872, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789274, Length=385, Percent_Identity=29.3506493506493, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI25146631, Length=439, Percent_Identity=26.1958997722096, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321694, Length=448, Percent_Identity=22.5446428571429, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920760, Length=385, Percent_Identity=23.8961038961039, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45274; Mature: 45274

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESAKPVAIFDVAVVGGGPAGLAAAIALSHAGARTALIARRVGYGDNRTTALLGGSIDL
CCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCHHH
LRELDVWPRCEADAAPLRVMRLVDDTGRLIRAPEVRFSAAEIGRDAFGYNIANRALMAAM
HHHCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEECHHHHCCHHHCHHHHHHHHHHHH
EARAAEAENLTRIDGEAEQVTPGDTVVTITTRQGDELSARLAVGADGRQSLCRKAACIGI
HHHHHHHHCCEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHH
TRRALDQAALTFNVAHSRPHKNTSTEFHTPHGPCVFVPLPGDRSSVVWVASPREVERLAA
HHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHH
LSDDELAEAAERRSHSILGRLEVGQGRNKFPLGIERPARFAGNRIVLVGESAHVLPPIGA
CCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCC
QGLNLGLRDAADIAEIVGDVLSSGEDPGASPALARFETARRSDVLSRTFAIDVANRSLLS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHH
DFLPIQTARAFGLHLISKVGPLRRLAMREGLAPSWRRRPHREPRSKAFSGEVDTGSSQEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHCCCCCCCCCCCCCC
ASKQ
CCCC
>Mature Secondary Structure
MNESAKPVAIFDVAVVGGGPAGLAAAIALSHAGARTALIARRVGYGDNRTTALLGGSIDL
CCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCCHHH
LRELDVWPRCEADAAPLRVMRLVDDTGRLIRAPEVRFSAAEIGRDAFGYNIANRALMAAM
HHHCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEECHHHHCCHHHCHHHHHHHHHHHH
EARAAEAENLTRIDGEAEQVTPGDTVVTITTRQGDELSARLAVGADGRQSLCRKAACIGI
HHHHHHHHCCEECCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHH
TRRALDQAALTFNVAHSRPHKNTSTEFHTPHGPCVFVPLPGDRSSVVWVASPREVERLAA
HHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHH
LSDDELAEAAERRSHSILGRLEVGQGRNKFPLGIERPARFAGNRIVLVGESAHVLPPIGA
CCCHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHCCCEEEEECCCCCCCCCCCC
QGLNLGLRDAADIAEIVGDVLSSGEDPGASPALARFETARRSDVLSRTFAIDVANRSLLS
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHH
DFLPIQTARAFGLHLISKVGPLRRLAMREGLAPSWRRRPHREPRSKAFSGEVDTGSSQEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHCCCCCCCCCCCCCC
ASKQ
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]