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The map label for this gene is purQ [H]

Identifier: 75675498

GI number: 75675498

Start: 1438812

End: 1439513

Strand: Direct

Name: purQ [H]

Synonym: Nwi_1306

Alternate gene names: 75675498

Gene position: 1438812-1439513 (Clockwise)

Preceding gene: 75675497

Following gene: 75675499

Centisome position: 42.29

GC content: 65.81

Gene sequence:

>702_bases
ATGAAGTCCGCAGTTCTCGTTTTTCCCGGCATCAATCGCGAGCGCGACATGGCGCGCGCGTTGCGGCTGGTGTCCGGGCG
CGAGCCCGCGATGGTGTGGCACGCGGAGACTTCGCTGCCCGAAGGCACCGATCTTGTCGTGGCGCCGGGCGGCTTTTCCT
ACGGCGACTACTTACGCTGCGGCGCCATCGCCGCGCGCGCGCCGGTCATGGACGCGGTGCGCGCCTTCGCGTCGGACGGC
GGTCTTGTGCTCGGCGTCTGCAACGGATTTCAGATTCTCTGCGAGTCCGGGTTGCTGCCCGGAATCCTCATGCGCAACGC
GCGGCTGAAGTTCATCTGTCATGACGTGCATCTGCGGGTCGAACGCTCGGATACGCCGTTCACGCGCGGCTACAATGCGG
GGCAGGTGATCCGCGTGCCCGTCGCCCATGGCGAGGGCAACTATGCCGCCGACGAGGACACCATTCGCCGCCTCGAAGGC
GAGGGGCGTGTGCTCTATCGTTATTGCTCGGCGTCAGGCGAGGTCGGCGACACGCATAATATCAACGGTGCGGCGCAGTC
GATCGCCGGCATCGTCAATGAACGCGGCAACGTACTCGGCATGATGCCGCATCCGGAAAATCACGTCGAAGATATCATGG
GCTGCACCGACGGGCGCGGCCTGTTCGCGGGCCTCGTCGCGCATCTGGAGCGGGCGGCGTGA

Upstream 100 bases:

>100_bases
GAAGGCGGAAGCCGCGCTCAAGGCGGCCGCCGACAAGCTGTTGGCCAATACCGTGATCGAGAACTATCGCGTCGAGGTTC
TGGGCTAGGCGACGCACGAC

Downstream 100 bases:

>100_bases
AGCAAATAGATGAAGTAGACATTTTTAAGTTTTGGAAAGAAGTCGGGCCGTCGGAAAAGGTTCATCCAGCAGATAGGGAA
ATCTTATTCAATGCTCCGAA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRCGAIAARAPVMDAVRAFASDG
GLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEG
EGRVLYRYCSASGEVGDTHNINGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA

Sequences:

>Translated_233_residues
MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRCGAIAARAPVMDAVRAFASDG
GLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEG
EGRVLYRYCSASGEVGDTHNINGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA
>Mature_233_residues
MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRCGAIAARAPVMDAVRAFASDG
GLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRVERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEG
EGRVLYRYCSASGEVGDTHNINGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=233, Percent_Identity=32.618025751073, Blast_Score=78, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321498, Length=235, Percent_Identity=31.4893617021277, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=31.0344827586207, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25001; Mature: 25001

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRAFASDGGLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHCCCEEEEEEEEEEEEE
ERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEGEGRVLYRYCSASGEVGDTHN
ECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSAVLVFPGINRERDMARALRLVSGREPAMVWHAETSLPEGTDLVVAPGGFSYGDYLRC
CCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHH
GAIAARAPVMDAVRAFASDGGLVLGVCNGFQILCESGLLPGILMRNARLKFICHDVHLRV
HHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHCCCEEEEEEEEEEEEE
ERSDTPFTRGYNAGQVIRVPVAHGEGNYAADEDTIRRLEGEGRVLYRYCSASGEVGDTHN
ECCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCC
INGAAQSIAGIVNERGNVLGMMPHPENHVEDIMGCTDGRGLFAGLVAHLERAA
CCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA