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The map label for this gene is rpiA [H]

Identifier: 75675414

GI number: 75675414

Start: 1342784

End: 1343482

Strand: Direct

Name: rpiA [H]

Synonym: Nwi_1221

Alternate gene names: 75675414

Gene position: 1342784-1343482 (Clockwise)

Preceding gene: 75675409

Following gene: 75675415

Centisome position: 39.47

GC content: 61.95

Gene sequence:

>699_bases
ATGACGATGGATGCATTGAAAAGACAGGCTGCGGCGCGTGCCCTTGAATATGTCGAGGACGGCATGAGGCTGGGTCTCGG
AACGGGATCCACCGCCAAGCACTTTGTCGAGCTTTTGGGCGAGCGCGTACGCGACGGGTTGAAGGTTGTCGGGGTGCCGA
CATCGGAAGCCACGCGGGCCGACGCGGAGCGGTGCGGCGTTCCCCTGACCACCCTGGACGATCTCGACAGGCTCGATCTG
ACGGTGGATGGCGCAGACGAAATCGATCCTGATCTCAATCTGACCAAGGGCGGTGGCGGGGCGCTTCTGCGCGAGAAAAT
CGTGGCTGCCGCGTCGGACCGCATGATCGTGATCGCTGACGAGACAAAATGGGTGGCGGGGCTCGGCCGCTTTCCCCTGC
CCATCGAAGTCATTCCGTTCGGGCTGGCCGCGACGCGACGGGCGATTACGGAGGTATTTGCAAAAGCCGGCGTTTCAGGT
GAACTGGCCGTCAGAAAGCGACCGGATGGCCATGCTTTTGTCACCGATGGCGGCCACTGGATTTTCGATGCCCATCTTGG
GCAGATACCTGATGCAAGCTATCTGGCCGGACTGTTGAATCCGATACCTGGCGTCGTCGAGCACGGCCTATTCATCGGCC
TCGCACGCGTGGCGATGCTGGCGGGCGCAGAGGGCATTCGTATTGTCGAGCGGCGGTAG

Upstream 100 bases:

>100_bases
GAGTTCGCTTGACCGAACCCGCATCGGCTGCAAAGCGAACGTCTGAGCCACATCAGGAAATGCCTCGCCAGCCGGAGCGG
GGTCGCAAATCGAGGTCCTC

Downstream 100 bases:

>100_bases
CGCCGCAATGAGGAGAATTGAGATGAGGGGACTTTCGAGATTTCTGCCTGCAAGATTTCTTCCTGCGGCGTGTCTTGCCG
TGGCGCTGGCGCTTCCAGCC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTMDALKRQAAARALEYVEDGMRLGLGTGSTAKHFVELLGERVRDGLKVVGVPTSEATRADAERCGVPLTTLDDLDRLDL
TVDGADEIDPDLNLTKGGGGALLREKIVAAASDRMIVIADETKWVAGLGRFPLPIEVIPFGLAATRRAITEVFAKAGVSG
ELAVRKRPDGHAFVTDGGHWIFDAHLGQIPDASYLAGLLNPIPGVVEHGLFIGLARVAMLAGAEGIRIVERR

Sequences:

>Translated_232_residues
MTMDALKRQAAARALEYVEDGMRLGLGTGSTAKHFVELLGERVRDGLKVVGVPTSEATRADAERCGVPLTTLDDLDRLDL
TVDGADEIDPDLNLTKGGGGALLREKIVAAASDRMIVIADETKWVAGLGRFPLPIEVIPFGLAATRRAITEVFAKAGVSG
ELAVRKRPDGHAFVTDGGHWIFDAHLGQIPDASYLAGLLNPIPGVVEHGLFIGLARVAMLAGAEGIRIVERR
>Mature_231_residues
TMDALKRQAAARALEYVEDGMRLGLGTGSTAKHFVELLGERVRDGLKVVGVPTSEATRADAERCGVPLTTLDDLDRLDLT
VDGADEIDPDLNLTKGGGGALLREKIVAAASDRMIVIADETKWVAGLGRFPLPIEVIPFGLAATRRAITEVFAKAGVSGE
LAVRKRPDGHAFVTDGGHWIFDAHLGQIPDASYLAGLLNPIPGVVEHGLFIGLARVAMLAGAEGIRIVERR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=39.7321428571429, Blast_Score=132, Evalue=3e-31,
Organism=Escherichia coli, GI1789280, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17551758, Length=231, Percent_Identity=39.3939393939394, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324669, Length=246, Percent_Identity=30.4878048780488, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281364072, Length=223, Percent_Identity=33.6322869955157, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24638; Mature: 24506

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMDALKRQAAARALEYVEDGMRLGLGTGSTAKHFVELLGERVRDGLKVVGVPTSEATRA
CCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHH
DAERCGVPLTTLDDLDRLDLTVDGADEIDPDLNLTKGGGGALLREKIVAAASDRMIVIAD
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEC
ETKWVAGLGRFPLPIEVIPFGLAATRRAITEVFAKAGVSGELAVRKRPDGHAFVTDGGHW
CCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCE
IFDAHLGQIPDASYLAGLLNPIPGVVEHGLFIGLARVAMLAGAEGIRIVERR
EEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
TMDALKRQAAARALEYVEDGMRLGLGTGSTAKHFVELLGERVRDGLKVVGVPTSEATRA
CHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHH
DAERCGVPLTTLDDLDRLDLTVDGADEIDPDLNLTKGGGGALLREKIVAAASDRMIVIAD
HHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCHHHHHHHHHHCCCCEEEEEC
ETKWVAGLGRFPLPIEVIPFGLAATRRAITEVFAKAGVSGELAVRKRPDGHAFVTDGGHW
CCHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCE
IFDAHLGQIPDASYLAGLLNPIPGVVEHGLFIGLARVAMLAGAEGIRIVERR
EEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA