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The map label for this gene is cycK [H]

Identifier: 75675386

GI number: 75675386

Start: 1298678

End: 1300663

Strand: Direct

Name: cycK [H]

Synonym: Nwi_1193

Alternate gene names: 75675386

Gene position: 1298678-1300663 (Clockwise)

Preceding gene: 75675385

Following gene: 75675387

Centisome position: 38.17

GC content: 64.15

Gene sequence:

>1986_bases
ATGATCGCCGAGGCCGGGCATTTCGCGCTGGTGCTGGCGCTCGGGCTCGCGCTGATCCAGTCCGTGGTTCCGATCATCGG
CGCAAGACTGCACGACGGCGCGTTGATGAACGTGGCGCGCTCGACCGCGCTGGCGCAATTGCTGTTTGTCGCCGCTTCGT
TTTTCGCGCTTGCGACGCTGTACGTGGTTTCCGATTTCTCGGTCCTCAACGTCTTCCAGAATTCCCACTCGCTGAAGCCG
ATGATCTACAAGATCACCGGCGTCTGGGGCAATCACGAAGGCTCCATGCTGTTGTGGGTGACGATCCTCGCTTTGTTCGG
CGGGCTGGTCGCGGCGTTCGGCAATAATCTTCCGCTGACGCTGCGCGCCCATGTGCTGGCGGTGCAGGGCTGGGTCGCGA
CCGCGTTCTACCTGTTCATCCTGCTGACATCGAATCCGTTCACGCGGATCGCCAGCCCGCCGATGGAGGGGCGCGATCTC
AATCCTGTGCTGCAGGATATCGGGCTCGCGGTACACCCGCCGATGCTTTATCTCGGCTATGTCGGCTTCTCCATCGCGTT
CTCCTTCGCGGTCGCCGCCCTGATCGAAGGCCGCATCGACGCAGCCTGGGCGCGCTGGGTGCGGCCATGGACGCTGGTGG
CGTGGATTTTCCTCACCCTCGGAATCGCGATGGGATCGTACTGGGCCTATTACGAACTCGGCTGGGGTGGCTGGTGGTTC
TGGGATCCGGTCGAGAACGCCTCGCTGATGCCGTGGCTGGCGGGAACGGCGCTGCTGCATTCCTCGGTGGTGATGGAAAA
GCGCAACGCGCTGAAAGTATGGACCATCCTGCTCGCGATCCTGACGTTCTCGCTGTCGCTGCTCGGCACCTTTTTGGTGC
GTTCGGGCGTGCTGACGTCAGTCCATGCCTTTGCTACCGACCCGACGCGCGGCGTCTTCATCCTGCTGATCCTCTGCACC
TTCATCGGCGGCAGCCTCACCTTGTTTATCTGGCGTGCGTCCACTCTGAAGCAGGGCGGCTTGTTCGCGCCGGTCTCGCG
CGAAGGCGCGCTCGTGCTCAACAACCTGTTCCTGACCACGGCCTGCGCCACCGTGTTCGTCGGCACGTTGTATCCGCTGG
CGCTCGAGGTCATCACCGGCAACAGGATTTCGGTCGGAGCGCCGTTCTTCAACCTGACGTTCGCGCCCTTGTTCGTCCCG
CTGCTGATCGCGGTGCCGTTCGGCCCGCTGCTGGCGTGGAAGCGCGGTGATCTGCTCGGTGCCTCTCAACGGCTGATCGC
CGCCGGGGTCGGCAGCGTGATCGCCGTGGCCGTGCTGTGGGCATGGACGCGTGGCGGCAGCACCTTCGCGCCGCTGGCGA
TCGGACTGGCGGTGTTCGTGATTATCGGCGCTCTCTGTGATCTCGCCGAGCGCGTCAACCTGTTTCGTGCGTCGCTGCCG
GTTTCCCTGCGCCGCGCGAAAGGATTGCCTCGTTCGGCGTGGGGCACGGTTTTCGCCCATGCCGGCCTCGGGGTAGCCTT
GATCGGCATCGTCTGCGAAACCACCTGGAATACCGAATACATCGCCTCGATGAAGATCAACGACGTGGCGCGGGTCGGTG
GCTACAGTCTGACGTTCGAGGGTACGACGCAGCATCAGCGATCCAACTATCGCGAAGATATCGCGCGCTTCACCGTCAGT
CGGGACGGGCAGCCGATCGCGGTCATGATGCCCTCCAAGCGTAACTTCACGACGCGCGCGGCTTCGACCACGGAAGCGGC
GCTGCTGACGCGTGGCGCGAGCCAGCTCTACATCTCGCTCGGTGAAGCCACCGCCGATGGGTCGATCGCGGTGCGCATCT
ATCACAAGCCTATGGTGTTGCTGATCTGGTTCGGTCCGGTCCTGATGGCCTTCGGCGGCGTGCTGTCGCTGTCAGACCGG
CGCTTGCGGGTCGGTGCGCCGAAACCGGCGAAGGCCGGCTGGCGCACGCTCCAGCCGGCGGAGTAA

Upstream 100 bases:

>100_bases
AAGAGGTCGCGGATGCCTTGAAGAAGCAGGGGCATTGGAAGGACGATTATGGCGCGCAGCCCGGAGCCGCTGAAGCTTCT
AGCAAGCAGGAGGTGTCGCA

Downstream 100 bases:

>100_bases
GGCTGCCATGCGTGAACTCGTACAAACCCTGTCGTCGTTGTGCGGACGGTGCATGGCGTGGAACAGGTTCCTGCCTGTTC
TCGGCGCGATCCTTTGTTTT

Product: cytochrome c-type biogenesis protein CcmF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 661; Mature: 661

Protein sequence:

>661_residues
MIAEAGHFALVLALGLALIQSVVPIIGARLHDGALMNVARSTALAQLLFVAASFFALATLYVVSDFSVLNVFQNSHSLKP
MIYKITGVWGNHEGSMLLWVTILALFGGLVAAFGNNLPLTLRAHVLAVQGWVATAFYLFILLTSNPFTRIASPPMEGRDL
NPVLQDIGLAVHPPMLYLGYVGFSIAFSFAVAALIEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWLAGTALLHSSVVMEKRNALKVWTILLAILTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILLILCT
FIGGSLTLFIWRASTLKQGGLFAPVSREGALVLNNLFLTTACATVFVGTLYPLALEVITGNRISVGAPFFNLTFAPLFVP
LLIAVPFGPLLAWKRGDLLGASQRLIAAGVGSVIAVAVLWAWTRGGSTFAPLAIGLAVFVIIGALCDLAERVNLFRASLP
VSLRRAKGLPRSAWGTVFAHAGLGVALIGIVCETTWNTEYIASMKINDVARVGGYSLTFEGTTQHQRSNYREDIARFTVS
RDGQPIAVMMPSKRNFTTRAASTTEAALLTRGASQLYISLGEATADGSIAVRIYHKPMVLLIWFGPVLMAFGGVLSLSDR
RLRVGAPKPAKAGWRTLQPAE

Sequences:

>Translated_661_residues
MIAEAGHFALVLALGLALIQSVVPIIGARLHDGALMNVARSTALAQLLFVAASFFALATLYVVSDFSVLNVFQNSHSLKP
MIYKITGVWGNHEGSMLLWVTILALFGGLVAAFGNNLPLTLRAHVLAVQGWVATAFYLFILLTSNPFTRIASPPMEGRDL
NPVLQDIGLAVHPPMLYLGYVGFSIAFSFAVAALIEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWLAGTALLHSSVVMEKRNALKVWTILLAILTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILLILCT
FIGGSLTLFIWRASTLKQGGLFAPVSREGALVLNNLFLTTACATVFVGTLYPLALEVITGNRISVGAPFFNLTFAPLFVP
LLIAVPFGPLLAWKRGDLLGASQRLIAAGVGSVIAVAVLWAWTRGGSTFAPLAIGLAVFVIIGALCDLAERVNLFRASLP
VSLRRAKGLPRSAWGTVFAHAGLGVALIGIVCETTWNTEYIASMKINDVARVGGYSLTFEGTTQHQRSNYREDIARFTVS
RDGQPIAVMMPSKRNFTTRAASTTEAALLTRGASQLYISLGEATADGSIAVRIYHKPMVLLIWFGPVLMAFGGVLSLSDR
RLRVGAPKPAKAGWRTLQPAE
>Mature_661_residues
MIAEAGHFALVLALGLALIQSVVPIIGARLHDGALMNVARSTALAQLLFVAASFFALATLYVVSDFSVLNVFQNSHSLKP
MIYKITGVWGNHEGSMLLWVTILALFGGLVAAFGNNLPLTLRAHVLAVQGWVATAFYLFILLTSNPFTRIASPPMEGRDL
NPVLQDIGLAVHPPMLYLGYVGFSIAFSFAVAALIEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWF
WDPVENASLMPWLAGTALLHSSVVMEKRNALKVWTILLAILTFSLSLLGTFLVRSGVLTSVHAFATDPTRGVFILLILCT
FIGGSLTLFIWRASTLKQGGLFAPVSREGALVLNNLFLTTACATVFVGTLYPLALEVITGNRISVGAPFFNLTFAPLFVP
LLIAVPFGPLLAWKRGDLLGASQRLIAAGVGSVIAVAVLWAWTRGGSTFAPLAIGLAVFVIIGALCDLAERVNLFRASLP
VSLRRAKGLPRSAWGTVFAHAGLGVALIGIVCETTWNTEYIASMKINDVARVGGYSLTFEGTTQHQRSNYREDIARFTVS
RDGQPIAVMMPSKRNFTTRAASTTEAALLTRGASQLYISLGEATADGSIAVRIYHKPMVLLIWFGPVLMAFGGVLSLSDR
RLRVGAPKPAKAGWRTLQPAE

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=645, Percent_Identity=45.4263565891473, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1790511, Length=362, Percent_Identity=46.1325966850829, Blast_Score=265, Evalue=5e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71396; Mature: 71396

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAEAGHFALVLALGLALIQSVVPIIGARLHDGALMNVARSTALAQLLFVAASFFALATL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVVSDFSVLNVFQNSHSLKPMIYKITGVWGNHEGSMLLWVTILALFGGLVAAFGNNLPLT
HHHHCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
LRAHVLAVQGWVATAFYLFILLTSNPFTRIASPPMEGRDLNPVLQDIGLAVHPPMLYLGY
EEEHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSIAFSFAVAALIEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
WDPVENASLMPWLAGTALLHSSVVMEKRNALKVWTILLAILTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFATDPTRGVFILLILCTFIGGSLTLFIWRASTLKQGGLFAPVSREGALVLNNLFLTT
HHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCCEECCCCCCCCEEHHHHHHHH
ACATVFVGTLYPLALEVITGNRISVGAPFFNLTFAPLFVPLLIAVPFGPLLAWKRGDLLG
HHHHHHHHHHHHHHHHEEECCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
ASQRLIAAGVGSVIAVAVLWAWTRGGSTFAPLAIGLAVFVIIGALCDLAERVNLFRASLP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSLRRAKGLPRSAWGTVFAHAGLGVALIGIVCETTWNTEYIASMKINDVARVGGYSLTFE
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCEEEEEC
GTTQHQRSNYREDIARFTVSRDGQPIAVMMPSKRNFTTRAASTTEAALLTRGASQLYISL
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCHHHHHHHCCCCEEEEEE
GEATADGSIAVRIYHKPMVLLIWFGPVLMAFGGVLSLSDRRLRVGAPKPAKAGWRTLQPA
CCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCEEECCCEEECCCCCCCCCCCCCCCCC
E
C
>Mature Secondary Structure
MIAEAGHFALVLALGLALIQSVVPIIGARLHDGALMNVARSTALAQLLFVAASFFALATL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVVSDFSVLNVFQNSHSLKPMIYKITGVWGNHEGSMLLWVTILALFGGLVAAFGNNLPLT
HHHHCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
LRAHVLAVQGWVATAFYLFILLTSNPFTRIASPPMEGRDLNPVLQDIGLAVHPPMLYLGY
EEEHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHH
VGFSIAFSFAVAALIEGRIDAAWARWVRPWTLVAWIFLTLGIAMGSYWAYYELGWGGWWF
HHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEE
WDPVENASLMPWLAGTALLHSSVVMEKRNALKVWTILLAILTFSLSLLGTFLVRSGVLTS
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
VHAFATDPTRGVFILLILCTFIGGSLTLFIWRASTLKQGGLFAPVSREGALVLNNLFLTT
HHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHCCCCEECCCCCCCCEEHHHHHHHH
ACATVFVGTLYPLALEVITGNRISVGAPFFNLTFAPLFVPLLIAVPFGPLLAWKRGDLLG
HHHHHHHHHHHHHHHHEEECCEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
ASQRLIAAGVGSVIAVAVLWAWTRGGSTFAPLAIGLAVFVIIGALCDLAERVNLFRASLP
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSLRRAKGLPRSAWGTVFAHAGLGVALIGIVCETTWNTEYIASMKINDVARVGGYSLTFE
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCEEEEEC
GTTQHQRSNYREDIARFTVSRDGQPIAVMMPSKRNFTTRAASTTEAALLTRGASQLYISL
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCHHHHHHHCCCCEEEEEE
GEATADGSIAVRIYHKPMVLLIWFGPVLMAFGGVLSLSDRRLRVGAPKPAKAGWRTLQPA
CCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCEEECCCEEECCCCCCCCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7715601; 12597275 [H]