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The map label for this gene is ftsA [H]

Identifier: 75675250

GI number: 75675250

Start: 1152782

End: 1154104

Strand: Direct

Name: ftsA [H]

Synonym: Nwi_1057

Alternate gene names: 75675250

Gene position: 1152782-1154104 (Clockwise)

Preceding gene: 75675249

Following gene: 75675251

Centisome position: 33.88

GC content: 65.91

Gene sequence:

>1323_bases
ATGACCAGCCTCGATTGCGGCCAGACCCCGAAAATGCGGCCCATGCAGCGCAACCGCAGCGCGCTGGTGGCGTCGCTGGA
CATTGGCACCAGCAAGATCGCCTGCATGATCGCAAGGCTGCGGCCGAGTGCGCCGAACGATGCGTTGCGCGGACGAACCC
ACGCGGTGGAACTGATCGGCTACAGCCAGATTCAATCGCGCGGCATGAAGGCCGGCGCCGTGACCGATCTCGCCCAGTGC
GAGCAGGCGGTTCGCCAGGCTGTATCGCTGGCCGAGCAGATGGCGAAGGTCCGGGTCGAATCCGTGCTGTTGCCGGTATC
GGCCGGGCGGTTGCAAGGCCAGTTGATCGAAGCGGCCTCCCACATTCAGGGCGGCGCGGTCACGCCGTCCGATATCAGCC
GGGTCACGTCGACCGGAATGCATCACGCCACGGCGTCCGGACGCACCGTGCTTCATGCGCTGCCCGCCGGCTATTCGCTC
GACGGCGTGAAGGGTATCCGCGACCCCCGTGGCATGGTGGCGCGCCGGTTCGGCGTCGACATGAACGTCGTGACCACGGA
AGCGACGGTTGCGAAAAACCTGATGCTGGCGGTGGAGCGCTGCCATCTCACCGTCGAAGCGATGGCTGCCAGTCCCTATG
TGGCCGGCCTGTCGGTGTTGACCGACGACGAGGTCGATCTCGGCGCCGCGGTCGTGGAGATGGGCGCGGGAACCACCACC
ATCGCGGTCTATTCAGCGGGACGCTTTATTTATGCGAGCGGTTTCGCCATCGGCGGACATCACGTCACCATGGATCTTGC
CCGCGGATTGGGCGCGTGCATTGCGGATGCCGAGCGAATCAAGACGTTATATGGCACGGTGCTGACGGGTGGCTCGGATG
TTCGCGAGCTGATGACGGTTCCCGCGGCCGGAGACAGTGACTGTGACGCGCCTCAGGTCGTGTCACGCGCGACCATCGCC
AACATCGTTCGTCAGCGTGTCGAGGAGATTTTTGAGATGGTCAGGGACCGGCTCGCGGATTCCCCATTTGCTGCCGAGCC
GCGCGCGCGCGTCGTGCTGAGCGGCGGGGCGTCGCAGTTGACCGGCGTTCCCGAACTCGCCTCGCGTGTTCTCGGCCGTC
CGGTCCGCATCGGCCGCCCCCTTGGCTTCGGCCGCCTGCCCAACGAGGCCAAGAGCGCTTCGTTCTCCGTCCCCACCGGG
CTGCTGGTGTACCCGCAATACGCACATCTGGAACATGTTGAGCCGCGGCGCACGCGGCAGGTTCGCACCGGGACGGACGG
CTATTTCGGAAAGGTCGGACGATGGCTCCGGGAGGGCTTCTGA

Upstream 100 bases:

>100_bases
ACATGCGTTTTCCCGATCGCCTGACCGTGCGGCTCTCGGAAGAGGCCGCGAAGGCGCGCGAAGAGCAGCTCAAGAAGTCC
AGCAAGAAGGCCGGCAGCGC

Downstream 100 bases:

>100_bases
TGAACTTTCCGCCGAATTGCAGATTCCCATCAACTCCGCGGTCGACGACCGCCGGCATAGCGACACCGCGCGTGTAATCG
AGAGGCAACCATGACCATCA

Product: cell division protein FtsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTSLDCGQTPKMRPMQRNRSALVASLDIGTSKIACMIARLRPSAPNDALRGRTHAVELIGYSQIQSRGMKAGAVTDLAQC
EQAVRQAVSLAEQMAKVRVESVLLPVSAGRLQGQLIEAASHIQGGAVTPSDISRVTSTGMHHATASGRTVLHALPAGYSL
DGVKGIRDPRGMVARRFGVDMNVVTTEATVAKNLMLAVERCHLTVEAMAASPYVAGLSVLTDDEVDLGAAVVEMGAGTTT
IAVYSAGRFIYASGFAIGGHHVTMDLARGLGACIADAERIKTLYGTVLTGGSDVRELMTVPAAGDSDCDAPQVVSRATIA
NIVRQRVEEIFEMVRDRLADSPFAAEPRARVVLSGGASQLTGVPELASRVLGRPVRIGRPLGFGRLPNEAKSASFSVPTG
LLVYPQYAHLEHVEPRRTRQVRTGTDGYFGKVGRWLREGF

Sequences:

>Translated_440_residues
MTSLDCGQTPKMRPMQRNRSALVASLDIGTSKIACMIARLRPSAPNDALRGRTHAVELIGYSQIQSRGMKAGAVTDLAQC
EQAVRQAVSLAEQMAKVRVESVLLPVSAGRLQGQLIEAASHIQGGAVTPSDISRVTSTGMHHATASGRTVLHALPAGYSL
DGVKGIRDPRGMVARRFGVDMNVVTTEATVAKNLMLAVERCHLTVEAMAASPYVAGLSVLTDDEVDLGAAVVEMGAGTTT
IAVYSAGRFIYASGFAIGGHHVTMDLARGLGACIADAERIKTLYGTVLTGGSDVRELMTVPAAGDSDCDAPQVVSRATIA
NIVRQRVEEIFEMVRDRLADSPFAAEPRARVVLSGGASQLTGVPELASRVLGRPVRIGRPLGFGRLPNEAKSASFSVPTG
LLVYPQYAHLEHVEPRRTRQVRTGTDGYFGKVGRWLREGF
>Mature_439_residues
TSLDCGQTPKMRPMQRNRSALVASLDIGTSKIACMIARLRPSAPNDALRGRTHAVELIGYSQIQSRGMKAGAVTDLAQCE
QAVRQAVSLAEQMAKVRVESVLLPVSAGRLQGQLIEAASHIQGGAVTPSDISRVTSTGMHHATASGRTVLHALPAGYSLD
GVKGIRDPRGMVARRFGVDMNVVTTEATVAKNLMLAVERCHLTVEAMAASPYVAGLSVLTDDEVDLGAAVVEMGAGTTTI
AVYSAGRFIYASGFAIGGHHVTMDLARGLGACIADAERIKTLYGTVLTGGSDVRELMTVPAAGDSDCDAPQVVSRATIAN
IVRQRVEEIFEMVRDRLADSPFAAEPRARVVLSGGASQLTGVPELASRVLGRPVRIGRPLGFGRLPNEAKSASFSVPTGL
LVYPQYAHLEHVEPRRTRQVRTGTDGYFGKVGRWLREGF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=426, Percent_Identity=31.4553990610329, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 46696; Mature: 46565

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLDCGQTPKMRPMQRNRSALVASLDIGTSKIACMIARLRPSAPNDALRGRTHAVELIG
CCCCCCCCCCCCCCHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHCCCCCEEEEHH
YSQIQSRGMKAGAVTDLAQCEQAVRQAVSLAEQMAKVRVESVLLPVSAGRLQGQLIEAAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
HIQGGAVTPSDISRVTSTGMHHATASGRTVLHALPAGYSLDGVKGIRDPRGMVARRFGVD
HCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
MNVVTTEATVAKNLMLAVERCHLTVEAMAASPYVAGLSVLTDDEVDLGAAVVEMGAGTTT
EEEEECHHHHHHHHHHHHHHHHHEEEHHHCCCHHHCEEEEECCCCHHHHHHHHCCCCCEE
IAVYSAGRFIYASGFAIGGHHVTMDLARGLGACIADAERIKTLYGTVLTGGSDVRELMTV
EEEEECCCEEEECCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PAAGDSDCDAPQVVSRATIANIVRQRVEEIFEMVRDRLADSPFAAEPRARVVLSGGASQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHH
TGVPELASRVLGRPVRIGRPLGFGRLPNEAKSASFSVPTGLLVYPQYAHLEHVEPRRTRQ
CCCHHHHHHHCCCCEECCCCCCCCCCCCHHCCCCCCCCCCEEECCCHHHHCCCCCHHHHH
VRTGTDGYFGKVGRWLREGF
CCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLDCGQTPKMRPMQRNRSALVASLDIGTSKIACMIARLRPSAPNDALRGRTHAVELIG
CCCCCCCCCCCCCHHCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHCCCCCEEEEHH
YSQIQSRGMKAGAVTDLAQCEQAVRQAVSLAEQMAKVRVESVLLPVSAGRLQGQLIEAAS
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHH
HIQGGAVTPSDISRVTSTGMHHATASGRTVLHALPAGYSLDGVKGIRDPRGMVARRFGVD
HCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
MNVVTTEATVAKNLMLAVERCHLTVEAMAASPYVAGLSVLTDDEVDLGAAVVEMGAGTTT
EEEEECHHHHHHHHHHHHHHHHHEEEHHHCCCHHHCEEEEECCCCHHHHHHHHCCCCCEE
IAVYSAGRFIYASGFAIGGHHVTMDLARGLGACIADAERIKTLYGTVLTGGSDVRELMTV
EEEEECCCEEEECCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PAAGDSDCDAPQVVSRATIANIVRQRVEEIFEMVRDRLADSPFAAEPRARVVLSGGASQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHH
TGVPELASRVLGRPVRIGRPLGFGRLPNEAKSASFSVPTGLLVYPQYAHLEHVEPRRTRQ
CCCHHHHHHHCCCCEECCCCCCCCCCCCHHCCCCCCCCCCEEECCCHHHHCCCCCHHHHH
VRTGTDGYFGKVGRWLREGF
CCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352931; 11481430 [H]