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The map label for this gene is pntB [H]

Identifier: 75675190

GI number: 75675190

Start: 1093500

End: 1094897

Strand: Direct

Name: pntB [H]

Synonym: Nwi_0997

Alternate gene names: 75675190

Gene position: 1093500-1094897 (Clockwise)

Preceding gene: 75675189

Following gene: 75675191

Centisome position: 32.14

GC content: 63.59

Gene sequence:

>1398_bases
ATGAATGCCGATCTTGCCGCGCTGCTTTACCTCGTCGCAGGTGTCTTGTTCATCCTGTCGCTGCGCGGACTGTCGAGTCC
GGCGTCGAGCCGCCGGGGCAATTTCCTCGGCATGGCCGGCATGGCGATCGCGGTCGCGACCACGCTCGCGGCGCATCCGC
CCGCTGACGCCGTGGCGTGGGTGCTGGTGATCCTCGGTGTTGCGATCGGCGGCGGCATCGGCGCGGTGATCGCGCGCCGG
GTGCCGATGACGTCGATGCCGGAACTGGTCGCGGCGTTTCACTCGCTGGTCGGCATGGCGGCGGTGCTGGTGGCCGCCGG
CGCGTTCTATGCGCCCGAAGCCTTCGAGATCGGAACGCCCGGCAACATCCATGCGCAGAGCCTGATCGAGATGTCGCTCG
GCGTGGCCATCGGCGCGCTGACGTTCACAGGCTCGGTGATCGCATTCCTCAAACTGTCCGGCCGGATGAGCGGCGCGCCG
ATCATCCTTCCCGCCCGTCACATCATAAACATCGCGCTCGCCCTCGCGCTGGTCTTCTTCATGTACGGGCTGGTGGTGTC
GGGCAGCGCGCTCGATTTCTGGCTGATCACCATTTTGGCTCTGGTGATCGGCGTGCTGCTGATCATTCCGATCGGCGGCG
CCGACATGCCGGTCGTGATCTCGATGCTGAACTCCTATTCCGGCTGGGCGGCGGCCGGCATCGGCTTCACGCTCGGTAAC
TCCGCGCTGATCATCACGGGGGCGCTGGTCGGCTCCTCCGGCGCGATCCTGTCCTACATCATGTGCCACGCCATGAACCG
GTCGTTCATCTCGGTGATCCTCGGCGGCTTCGGCGGCGAGACGGCGGCGGCGGGCGGCGCCGGGGGTGAGCAGAAGCCGG
CAAAGCTTGGCTCGGCGGACGACGCCGCTTTCATCATGAAGAATGCCTCGAAGGTCATCATCGTGCCGGGCTACGGCATG
GCGGTCGCGCAGGCGCAGCATGCGCTGCGCGAATTGGCGGACTCACTGAAGAAGGAAGGCGTCGAGGTCAAATACGCGAT
CCATCCGGTCGCGGGCCGAATGCCCGGCCATATGAATGTGCTGCTGGCGGAAGCCAATGTGCCTTACGACGAAGTTTTTG
AGCTCGAGGATATCAATTCGGAGTTCGCTCAGGCCGACGTGGCATTCGTCATCGGCGCCAACGACGTCACCAACCCCGCG
GCGGAGGACGACAAGTCTTCGCCGATCTATGGCATGCCGGTGTTGCAAGTCTGGAAGGCCGGCACGGTGATGTTCATCAA
GCGTTCGCTGGCATCGGGTTATGCCGGTATCGATAATCCACTGTTCTATCGGGATAACACCATGATGCTGCTTGGCGACG
CCAAGAAGATGACGGAGAATATCGTCAAGGGAATGTAA

Upstream 100 bases:

>100_bases
CATCGCCGATCCGGGATCGCCATAGTTTGGGACGGTTCCGGTTCCGCGCCGCATCGCTTTGCGCTGCGCCGCGCCCGGGA
CGAGACGCCGGGGCTCCGCC

Downstream 100 bases:

>100_bases
CGCGTCGTAATTCAACAGCGGAGGCCGGCATGGCGGATGATAAGGCGAAGCGCGGCGGAAGCGATGGTCGATTGATCGCG
CTGCGTGAGGCTTACGAGGT

Product: NAD/NADP transhydrogenase beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MNADLAALLYLVAGVLFILSLRGLSSPASSRRGNFLGMAGMAIAVATTLAAHPPADAVAWVLVILGVAIGGGIGAVIARR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPEAFEIGTPGNIHAQSLIEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHIINIALALALVFFMYGLVVSGSALDFWLITILALVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCHAMNRSFISVILGGFGGETAAAGGAGGEQKPAKLGSADDAAFIMKNASKVIIVPGYGM
AVAQAQHALRELADSLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEDDKSSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKGM

Sequences:

>Translated_465_residues
MNADLAALLYLVAGVLFILSLRGLSSPASSRRGNFLGMAGMAIAVATTLAAHPPADAVAWVLVILGVAIGGGIGAVIARR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPEAFEIGTPGNIHAQSLIEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHIINIALALALVFFMYGLVVSGSALDFWLITILALVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCHAMNRSFISVILGGFGGETAAAGGAGGEQKPAKLGSADDAAFIMKNASKVIIVPGYGM
AVAQAQHALRELADSLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEDDKSSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKGM
>Mature_465_residues
MNADLAALLYLVAGVLFILSLRGLSSPASSRRGNFLGMAGMAIAVATTLAAHPPADAVAWVLVILGVAIGGGIGAVIARR
VPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPEAFEIGTPGNIHAQSLIEMSLGVAIGALTFTGSVIAFLKLSGRMSGAP
IILPARHIINIALALALVFFMYGLVVSGSALDFWLITILALVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
SALIITGALVGSSGAILSYIMCHAMNRSFISVILGGFGGETAAAGGAGGEQKPAKLGSADDAAFIMKNASKVIIVPGYGM
AVAQAQHALRELADSLKKEGVEVKYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPA
AEDDKSSPIYGMPVLQVWKAGTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKGM

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=472, Percent_Identity=46.6101694915254, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI122939153, Length=472, Percent_Identity=46.6101694915254, Blast_Score=387, Evalue=1e-107,
Organism=Escherichia coli, GI1787886, Length=471, Percent_Identity=53.7154989384289, Blast_Score=469, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17550456, Length=459, Percent_Identity=48.1481481481481, Blast_Score=389, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 47992; Mature: 47992

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADLAALLYLVAGVLFILSLRGLSSPASSRRGNFLGMAGMAIAVATTLAAHPPADAVAW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEHHHHHHHHHHHHHCCCCHHHHHH
VLVILGVAIGGGIGAVIARRVPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPEAFEIGTP
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
GNIHAQSLIEMSLGVAIGALTFTGSVIAFLKLSGRMSGAPIILPARHIINIALALALVFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHH
MYGLVVSGSALDFWLITILALVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCEEECC
SALIITGALVGSSGAILSYIMCHAMNRSFISVILGGFGGETAAAGGAGGEQKPAKLGSAD
CEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAFIMKNASKVIIVPGYGMAVAQAQHALRELADSLKKEGVEVKYAIHPVAGRMPGHMNV
CHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEE
LLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAEDDKSSPIYGMPVLQVWKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
GTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKGM
CHHHHHHHHHHCCCCCCCCCEEEECCEEEEEECHHHHHHHHHCCC
>Mature Secondary Structure
MNADLAALLYLVAGVLFILSLRGLSSPASSRRGNFLGMAGMAIAVATTLAAHPPADAVAW
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCEEEHHHHHHHHHHHHHCCCCHHHHHH
VLVILGVAIGGGIGAVIARRVPMTSMPELVAAFHSLVGMAAVLVAAGAFYAPEAFEIGTP
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCC
GNIHAQSLIEMSLGVAIGALTFTGSVIAFLKLSGRMSGAPIILPARHIINIALALALVFF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHHHHHH
MYGLVVSGSALDFWLITILALVIGVLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGN
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCEEECC
SALIITGALVGSSGAILSYIMCHAMNRSFISVILGGFGGETAAAGGAGGEQKPAKLGSAD
CEEEEEEEEECCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
DAAFIMKNASKVIIVPGYGMAVAQAQHALRELADSLKKEGVEVKYAIHPVAGRMPGHMNV
CHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEE
LLAEANVPYDEVFELEDINSEFAQADVAFVIGANDVTNPAAEDDKSSPIYGMPVLQVWKA
EEEECCCCHHHHHHHHHCCHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHCC
GTVMFIKRSLASGYAGIDNPLFYRDNTMMLLGDAKKMTENIVKGM
CHHHHHHHHHHCCCCCCCCCEEEECCEEEEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]