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The map label for this gene is sodB [H]

Identifier: 75675106

GI number: 75675106

Start: 1001153

End: 1001758

Strand: Direct

Name: sodB [H]

Synonym: Nwi_0913

Alternate gene names: 75675106

Gene position: 1001153-1001758 (Clockwise)

Preceding gene: 75675104

Following gene: 75675107

Centisome position: 29.43

GC content: 55.94

Gene sequence:

>606_bases
ATGACCTTTACGCTTCCGAACCTGCCATATTCCCATGACGCGCTCGCGCCCCATATGTCCAAGGAAACCTTGGAATATCA
TCATGATAAGCACCATCAGGCTTACGTGACCAACGGTAATAACGCGATCAAGGGGACCGAGTTCGAGGGCAAGTCGCTCG
AGGATATCGTGAGAAGCTCGTACGGCAAGAGCGCGTCCGTGGGCGTGTTCAACAACGCCGGCCAGCACTACAATCACCTG
CATTTCTGGAACTGGATGAAGCCCAACGGCGGCGGCGACAAGCTTCCCGGTCGCCTCGAGAAGAAGATCATCGAGGATTT
CGGCAGCCTAGAGAAATTCAAAGCTGATTTCGCCGCAGCCGGCGCCGGACAGTTCGGTTCGGGCTGGGCATGGCTTCAGG
TGAAGAACGGCAAGCTGGAAGTATCCAAGACTCCGAACGCCGAAAACCCGCTGATTCACAACGCGACCCCCATTCTCGGC
TGCGACGTCTGGGAGCACTCCTACTACATCGACTATCGCAACCGCCGTCCGGACTATCTCAAGGCGTTCCTCGATCATCT
CGTGAACTGGGATTACGTGGATCAACTTTACTCCAAGGTCGCCTGA

Upstream 100 bases:

>100_bases
TTATGGTATGTAACGGCAGGTGTCGTACTGGCGACGGAAACCCCTGACCGGGTTTCGCCGGGGCCCCTTACAAACTCCCA
ACAATTCGGACAAACAACCC

Downstream 100 bases:

>100_bases
CCGGCGGTCAGGTCGACTCCTGGAAGGACTCCAGAAGGCGGCACGGCGGTGCCGCCTTTTTTGCGCGCGTGTGATTCCCG
AAGCCATTGTCTTGTTCACT

Product: manganese and iron superoxide dismutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTFTLPNLPYSHDALAPHMSKETLEYHHDKHHQAYVTNGNNAIKGTEFEGKSLEDIVRSSYGKSASVGVFNNAGQHYNHL
HFWNWMKPNGGGDKLPGRLEKKIIEDFGSLEKFKADFAAAGAGQFGSGWAWLQVKNGKLEVSKTPNAENPLIHNATPILG
CDVWEHSYYIDYRNRRPDYLKAFLDHLVNWDYVDQLYSKVA

Sequences:

>Translated_201_residues
MTFTLPNLPYSHDALAPHMSKETLEYHHDKHHQAYVTNGNNAIKGTEFEGKSLEDIVRSSYGKSASVGVFNNAGQHYNHL
HFWNWMKPNGGGDKLPGRLEKKIIEDFGSLEKFKADFAAAGAGQFGSGWAWLQVKNGKLEVSKTPNAENPLIHNATPILG
CDVWEHSYYIDYRNRRPDYLKAFLDHLVNWDYVDQLYSKVA
>Mature_200_residues
TFTLPNLPYSHDALAPHMSKETLEYHHDKHHQAYVTNGNNAIKGTEFEGKSLEDIVRSSYGKSASVGVFNNAGQHYNHLH
FWNWMKPNGGGDKLPGRLEKKIIEDFGSLEKFKADFAAAGAGQFGSGWAWLQVKNGKLEVSKTPNAENPLIHNATPILGC
DVWEHSYYIDYRNRRPDYLKAFLDHLVNWDYVDQLYSKVA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=200, Percent_Identity=41, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI67782305, Length=200, Percent_Identity=41, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI67782309, Length=198, Percent_Identity=34.3434343434343, Blast_Score=113, Evalue=1e-25,
Organism=Escherichia coli, GI1787946, Length=197, Percent_Identity=57.8680203045685, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1790342, Length=200, Percent_Identity=46.5, Blast_Score=178, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17506561, Length=201, Percent_Identity=34.3283582089552, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17569479, Length=198, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321796, Length=203, Percent_Identity=36.4532019704434, Blast_Score=106, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136812, Length=194, Percent_Identity=40.7216494845361, Blast_Score=129, Evalue=1e-30,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 22824; Mature: 22692

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTLPNLPYSHDALAPHMSKETLEYHHDKHHQAYVTNGNNAIKGTEFEGKSLEDIVRSS
CEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
YGKSASVGVFNNAGQHYNHLHFWNWMKPNGGGDKLPGRLEKKIIEDFGSLEKFKADFAAA
CCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GAGQFGSGWAWLQVKNGKLEVSKTPNAENPLIHNATPILGCDVWEHSYYIDYRNRRPDYL
CCCCCCCCEEEEEEECCEEEEECCCCCCCCEEECCCCEEECEEECCEEEEECCCCCHHHH
KAFLDHLVNWDYVDQLYSKVA
HHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
TFTLPNLPYSHDALAPHMSKETLEYHHDKHHQAYVTNGNNAIKGTEFEGKSLEDIVRSS
EEECCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
YGKSASVGVFNNAGQHYNHLHFWNWMKPNGGGDKLPGRLEKKIIEDFGSLEKFKADFAAA
CCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
GAGQFGSGWAWLQVKNGKLEVSKTPNAENPLIHNATPILGCDVWEHSYYIDYRNRRPDYL
CCCCCCCCEEEEEEECCEEEEECCCCCCCCEEECCCCEEECEEECCEEEEECCCCCHHHH
KAFLDHLVNWDYVDQLYSKVA
HHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10419947; 11481430 [H]