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The map label for this gene is 75674948

Identifier: 75674948

GI number: 75674948

Start: 837798

End: 838370

Strand: Direct

Name: 75674948

Synonym: Nwi_0752

Alternate gene names: NA

Gene position: 837798-838370 (Clockwise)

Preceding gene: 75674947

Following gene: 75674949

Centisome position: 24.63

GC content: 64.22

Gene sequence:

>573_bases
ATGGTCGTTCTCAACCGAATCTACACGCGAACCGGTGACGACGGCACGACCGCGCTCGGCACCGGTGAGCGCCGCCCGAA
ATACGATCTCCGCGTCGGCGCCTACGGGACCGTTGATGAGACCAACGCCGCTATCGGCGTGGTCCGGCTGCATCTTTCCG
GCGCGCCCGACCTTGATGGAATGTTGGGCCGCATCCAGAATGATCTGTTCGATCTTGGCGCTGACCTTGCGGTGCCTCAG
CGCGAGGGCAAGGCCGAACGGCTTCGCGTGCTGACCAGCCAGGTCGCGCGCCTGGAGAATGAGATCGACAGCCTCAATGC
GGGGCTCCCTGATCTGACATCATTCGTGCTGCCGGGAGGGACGCCCGCCGCGGCGTATCTTCATCTGGCCCGAACCATTT
GCCGCCGCGCCGAACGCATGATGGTGGAACTCGCTGCGCGGCCGGGCGAGCCGGTCAGCGAGGCCGCCGTGAGATACATG
AACCGGCTGTCCGATTTTCTGTTCGTCGCCAGCCGTTTTATGAACGCCATGGGCGCGGGCGATGTGCTCTGGGTGCCCGG
TCAAAACAGATGA

Upstream 100 bases:

>100_bases
GATGGCGGGTATTCCTGCAGTTCGTTGCGATCATCATCGCGATGGTCACGATCTGGATGCTGGGTCAGTGACGGACTGAT
GGCCTGGCGTCGGAGGATCG

Downstream 100 bases:

>100_bases
CCCGCCCGCCGGTGGCGTCCTGGATGCGTGAGGAACGAGGACCGCGTTTTTTGGCCTTCCCGCGTTGACCACCGGAAACG
GGACCTTTAGGTTCCGCGCC

Product: cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MVVLNRIYTRTGDDGTTALGTGERRPKYDLRVGAYGTVDETNAAIGVVRLHLSGAPDLDGMLGRIQNDLFDLGADLAVPQ
REGKAERLRVLTSQVARLENEIDSLNAGLPDLTSFVLPGGTPAAAYLHLARTICRRAERMMVELAARPGEPVSEAAVRYM
NRLSDFLFVASRFMNAMGAGDVLWVPGQNR

Sequences:

>Translated_190_residues
MVVLNRIYTRTGDDGTTALGTGERRPKYDLRVGAYGTVDETNAAIGVVRLHLSGAPDLDGMLGRIQNDLFDLGADLAVPQ
REGKAERLRVLTSQVARLENEIDSLNAGLPDLTSFVLPGGTPAAAYLHLARTICRRAERMMVELAARPGEPVSEAAVRYM
NRLSDFLFVASRFMNAMGAGDVLWVPGQNR
>Mature_190_residues
MVVLNRIYTRTGDDGTTALGTGERRPKYDLRVGAYGTVDETNAAIGVVRLHLSGAPDLDGMLGRIQNDLFDLGADLAVPQ
REGKAERLRVLTSQVARLENEIDSLNAGLPDLTSFVLPGGTPAAAYLHLARTICRRAERMMVELAARPGEPVSEAAVRYM
NRLSDFLFVASRFMNAMGAGDVLWVPGQNR

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=182, Percent_Identity=39.5604395604396, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI115534154, Length=168, Percent_Identity=36.3095238095238, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 20643; Mature: 20643

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLNRIYTRTGDDGTTALGTGERRPKYDLRVGAYGTVDETNAAIGVVRLHLSGAPDLDG
CEEECCHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHEEEEEEEECCCCCHHH
MLGRIQNDLFDLGADLAVPQREGKAERLRVLTSQVARLENEIDSLNAGLPDLTSFVLPGG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
TPAAAYLHLARTICRRAERMMVELAARPGEPVSEAAVRYMNRLSDFLFVASRFMNAMGAG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVLWVPGQNR
CEEECCCCCC
>Mature Secondary Structure
MVVLNRIYTRTGDDGTTALGTGERRPKYDLRVGAYGTVDETNAAIGVVRLHLSGAPDLDG
CEEECCHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHEEEEEEEECCCCCHHH
MLGRIQNDLFDLGADLAVPQREGKAERLRVLTSQVARLENEIDSLNAGLPDLTSFVLPGG
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
TPAAAYLHLARTICRRAERMMVELAARPGEPVSEAAVRYMNRLSDFLFVASRFMNAMGAG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVLWVPGQNR
CEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]